메뉴 건너뛰기




Volumn 90, Issue 6, 2004, Pages 1359-1370

Apoptotic cell death influences the signaling activity of the amyloid precursor protein through ShcA and Grb2 adaptor proteins in neuroblastoma SH-SY5Y cells

Author keywords

Alzheimer's disease; Amyloid precursor protein; Apoptosis; Signal transductions; Tyrosine phosphorylation

Indexed keywords

ADAPTOR PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTYROSINE; PROTEIN; TYROSINE;

EID: 4544302611     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02618.x     Document Type: Article
Times cited : (23)

References (48)
  • 1
    • 0037020265 scopus 로고    scopus 로고
    • Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nek, WIP, and Grb2
    • Benesch S., Lommel S., Steifen A., Stradal T. E., Scaplehorn N., Way M., Wehland J. and Rottner K. (2002) Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nek, WIP, and Grb2. J. Biol. Chem. 277, 37771-37776.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37771-37776
    • Benesch, S.1    Lommel, S.2    Steifen, A.3    Stradal, T.E.4    Scaplehorn, N.5    Way, M.6    Wehland, J.7    Rottner, K.8
  • 2
    • 0030788099 scopus 로고    scopus 로고
    • Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines
    • Boix J., Llecha N., Yuste V. J. and Comella J. X. (1997) Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines. Neuropharmacology 36, 811-821.
    • (1997) Neuropharmacology , vol.36 , pp. 811-821
    • Boix, J.1    Llecha, N.2    Yuste, V.J.3    Comella, J.X.4
  • 3
    • 0029805132 scopus 로고    scopus 로고
    • The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein
    • Borg J. P., Ooi J., Levy E. and Margolis B. (1996) The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein. Mol. Cell Biol. 16, 6229-6241.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 6229-6241
    • Borg, J.P.1    Ooi, J.2    Levy, E.3    Margolis, B.4
  • 4
    • 0037474287 scopus 로고    scopus 로고
    • Presenilin-1 regulates intracellular trafficking and cell surface delivery of β-amyloid precursor protein
    • Cai D., Leem J. Y., Greenfield J. P. et al. (2003) Presenilin-1 regulates intracellular trafficking and cell surface delivery of β-amyloid precursor protein. J. Biol. Chem. 278, 3446-3454.
    • (2003) J. Biol. Chem. , vol.278 , pp. 3446-3454
    • Cai, D.1    Leem, J.Y.2    Greenfield, J.P.3
  • 5
    • 0035816661 scopus 로고    scopus 로고
    • A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60
    • Cao X. and Sudhof T. C. (2001) A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293, 115-120.
    • (2001) Science , vol.293 , pp. 115-120
    • Cao, X.1    Sudhof, T.C.2
  • 6
    • 0032213730 scopus 로고    scopus 로고
    • Emerging roles for SH2/PTB-containing She adaptor proteins in the developing mammalian brain
    • Cattaneo E. and Pelicci P. G. (1998) Emerging roles for SH2/PTB-containing She adaptor proteins in the developing mammalian brain. Trends Neurosci. 21, 476-481.
    • (1998) Trends Neurosci. , vol.21 , pp. 476-481
    • Cattaneo, E.1    Pelicci, P.G.2
  • 7
    • 0035137171 scopus 로고    scopus 로고
    • Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: Implications for human breast cancer
    • Dankort D., Maslikowski B., Wamer N. et al. (2001) Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer. Mol. Cell Biol. 21, 1540-1551.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 1540-1551
    • Dankort, D.1    Maslikowski, B.2    Wamer, N.3
  • 8
    • 0035909901 scopus 로고    scopus 로고
    • The γ-secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus
    • Gao Y. and Pimplikar S. W. (2001) The γ-secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus. Proc. Natl Acad. Sci. USA 98, 14979-14984.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14979-14984
    • Gao, Y.1    Pimplikar, S.W.2
  • 9
    • 0026539090 scopus 로고
    • Processing of the amyloid protein precursor to potentially amyloidogenic derivatives
    • Golde T. E., Estas S., Younkin L. H., Selkoe D. J. and Younkin S. G. (1992) Processing of the amyloid protein precursor to potentially amyloidogenic derivatives. Science 255, 728-730.
    • (1992) Science , vol.255 , pp. 728-730
    • Golde, T.E.1    Estas, S.2    Younkin, L.H.3    Selkoe, D.J.4    Younkin, S.G.5
  • 10
    • 0037052633 scopus 로고    scopus 로고
    • MPP+ increases α-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells
    • Gomez-Santos C., Ferrer I., Reiriz J., Vinals F., Barrachina M. and Ambrosio S. (2002) MPP+ increases α-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells. Brain Res. 935, 32-39.
    • (2002) Brain Res. , vol.935 , pp. 32-39
    • Gomez-Santos, C.1    Ferrer, I.2    Reiriz, J.3    Vinals, F.4    Barrachina, M.5    Ambrosio, S.6
  • 11
    • 0035253794 scopus 로고    scopus 로고
    • Hyperphosphorylation of tau is mediated by ERK activation during anticancer drug-induced apoptosis in neuroblastoma cells
    • Guise S., Braguer D., Carles G., Delacourte A. and Briand C. (2001) Hyperphosphorylation of tau is mediated by ERK activation during anticancer drug-induced apoptosis in neuroblastoma cells. J. Neurosci. Res. 63, 257-267.
    • (2001) J. Neurosci. Res. , vol.63 , pp. 257-267
    • Guise, S.1    Braguer, D.2    Carles, G.3    Delacourte, A.4    Briand, C.5
  • 12
    • 0034329291 scopus 로고    scopus 로고
    • Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members
    • Heber S., Herms J., Gajic V. et al. (2000) Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. J. Neurosci. 20,7951-7963.
    • (2000) J. Neurosci. , vol.20 , pp. 7951-7963
    • Heber, S.1    Herms, J.2    Gajic, V.3
  • 13
    • 0033066680 scopus 로고    scopus 로고
    • The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids
    • Howell B. W., Lanier L. M., Frank R., Gertler F. B. and Cooper J. A. (1999) The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids. Mol. Cell Biol. 19, 5179-5188.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 5179-5188
    • Howell, B.W.1    Lanier, L.M.2    Frank, R.3    Gertler, F.B.4    Cooper, J.A.5
  • 14
    • 0036677928 scopus 로고    scopus 로고
    • Direct visualization of the γ-secretase-generated carboxyl-terminal domain of the amyloid precursor protein: Association with Fe65 and translocation to the nucleus
    • Kinoshita A., Whelan C. M., Smith C. J., Berezovska O. and Hyman B. T. (2002) Direct visualization of the γ-secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus. J. Neurochem. 82, 839-847.
    • (2002) J. Neurochem. , vol.82 , pp. 839-847
    • Kinoshita, A.1    Whelan, C.M.2    Smith, C.J.3    Berezovska, O.4    Hyman, B.T.5
  • 15
    • 0037079063 scopus 로고    scopus 로고
    • Fear memory formation involves p190 RhoGAP and ROCK proteins through a GRB2-mediated complex
    • Lamprecht R., Farb C. R. and LeDoux J. E. (2002) Fear memory formation involves p190 RhoGAP and ROCK proteins through a GRB2-mediated complex. Neuron 36, 727-738.
    • (2002) Neuron , vol.36 , pp. 727-738
    • Lamprecht, R.1    Farb, C.R.2    LeDoux, J.E.3
  • 16
    • 12144286502 scopus 로고    scopus 로고
    • Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer's disease patients
    • Li R., Lindholm K., Yang L. B. et al. (2004) Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer's disease patients. Proc. Natl. Acad. Sci. USA 101, 3632-3637.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 3632-3637
    • Li, R.1    Lindholm, K.2    Yang, L.B.3
  • 17
    • 0034727885 scopus 로고    scopus 로고
    • Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FASL-caspase-8 signaling pathway
    • Lopez E. and Ferrer I. (2000) Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FASL-caspase-8 signaling pathway. Brain Res. Mol. Brain Res. 85, 61-67.
    • (2000) Brain Res. Mol. Brain Res. , vol.85 , pp. 61-67
    • Lopez, E.1    Ferrer, I.2
  • 19
    • 0035900875 scopus 로고    scopus 로고
    • β-secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations
    • McPhie D. L., Golde T., Eckman C. B., Yager D., Brant J. B. and Neve R. L. (2001) β-Secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations. Brain Res. Mol. Brain Res. 97, 103-113.
    • (2001) Brain Res. Mol. Brain Res. , vol.97 , pp. 103-113
    • McPhie, D.L.1    Golde, T.2    Eckman, C.B.3    Yager, D.4    Brant, J.B.5    Neve, R.L.6
  • 20
    • 0345829921 scopus 로고    scopus 로고
    • Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre
    • Martinu L., Santiago-Walker A., Qi H. and Chou M. M. (2002) Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre. J. Biol. Chem. 277, 50996-51002.
    • (2002) J. Biol. Chem. , vol.277 , pp. 50996-51002
    • Martinu, L.1    Santiago-Walker, A.2    Qi, H.3    Chou, M.M.4
  • 22
    • 0034797234 scopus 로고    scopus 로고
    • The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from γ-secretase
    • Nunan J., Shearman M. S., Checler F., Cappai R., Evin G., Beyreuther K., Masters C. L. and Small D. H. (2001) The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from γ-secretase. Eur. J. Biochem. 268, 5329-5336.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 5329-5336
    • Nunan, J.1    Shearman, M.S.2    Checler, F.3    Cappai, R.4    Evin, G.5    Beyreuther, K.6    Masters, C.L.7    Small, D.H.8
  • 23
    • 0029862137 scopus 로고    scopus 로고
    • Age-dependent neuronal and synaptic degeneration in mice transgenic for the C-terminus of the amyloid precursor protein
    • Oster-Granite M. L., McPhie D. L., Greenan J. and Neve R. L. (1996) Age-dependent neuronal and synaptic degeneration in mice transgenic for the C-terminus of the amyloid precursor protein. J. Neurosci. 16, 6732-6741.
    • (1996) J. Neurosci. , vol.16 , pp. 6732-6741
    • Oster-Granite, M.L.1    McPhie, D.L.2    Greenan, J.3    Neve, R.L.4
  • 25
    • 0026777369 scopus 로고
    • A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction
    • Pelicci G., Lanfrancone L., Grignani F. et al. (1992) A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell 70, 93-104.
    • (1992) Cell , vol.70 , pp. 93-104
    • Pelicci, G.1    Lanfrancone, L.2    Grignani, F.3
  • 26
    • 0036788763 scopus 로고    scopus 로고
    • The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway
    • Pelicci G., Troglio F., Bodini A., Melillo R. M., Pettirossi V., Coda L., De Giuseppe A., Santoro M. and Pelicci P. G. (2002) The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. Mol. Cell Biol. 22, 7351-7363.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 7351-7363
    • Pelicci, G.1    Troglio, F.2    Bodini, A.3    Melillo, R.M.4    Pettirossi, V.5    Coda, L.6    De Giuseppe, A.7    Santoro, M.8    Pelicci, P.G.9
  • 27
    • 0038660689 scopus 로고    scopus 로고
    • p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling
    • Puto L. A., Pestonjamasp K., King C. C. and Bokoch G. M. (2003) p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling. J. Biol. Chem. 278, 9388-9393.
    • (2003) J. Biol. Chem. , vol.278 , pp. 9388-9393
    • Puto, L.A.1    Pestonjamasp, K.2    King, C.C.3    Bokoch, G.M.4
  • 29
    • 0035118308 scopus 로고    scopus 로고
    • Amino-terminal modification and tyrosine phosphorylation of carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain
    • Russo C., Salis S., Dolcini V., Venezia V., Song X. H., Teller J. K. and Schettini G. (2001) Amino-terminal modification and tyrosine phosphorylation of carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain. Neurobiol. Dis 8, 173-180.
    • (2001) Neurobiol. Dis. , vol.8 , pp. 173-180
    • Russo, C.1    Salis, S.2    Dolcini, V.3    Venezia, V.4    Song, X.H.5    Teller, J.K.6    Schettini, G.7
  • 30
    • 0037144497 scopus 로고    scopus 로고
    • Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain
    • Russo C., Dolcini V., Salis S., Venezia V., Zambrano N., Russo T. and Schettini G. (2002) Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain. J. Biol. Chem. 277, 35282-35288.
    • (2002) J. Biol. Chem. , vol.277 , pp. 35282-35288
    • Russo, C.1    Dolcini, V.2    Salis, S.3    Venezia, V.4    Zambrano, N.5    Russo, T.6    Schettini, G.7
  • 31
    • 85047700252 scopus 로고    scopus 로고
    • Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis
    • Saucier C., Papavasiliou V., Palazzo A., Naujokas M. A., Kremer R. and Park M. (2002) Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis. Oncogene 21, 1800-1811.
    • (2002) Oncogene , vol.21 , pp. 1800-1811
    • Saucier, C.1    Papavasiliou, V.2    Palazzo, A.3    Naujokas, M.A.4    Kremer, R.5    Park, M.6
  • 32
    • 0036462590 scopus 로고    scopus 로고
    • Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's β-amyloid precursor protein (APP)
    • Scheinfeld M. H., Roncarati R., Vito P., Lopez P. A., Abdallah M. and D'Adamio L. (2002) Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's β-amyloid precursor protein (APP). J. Biol. Chem. 277, 3767-3775.
    • (2002) J. Biol. Chem. , vol.277 , pp. 3767-3775
    • Scheinfeld, M.H.1    Roncarati, R.2    Vito, P.3    Lopez, P.A.4    Abdallah, M.5    D'Adamio, L.6
  • 33
    • 0036855661 scopus 로고    scopus 로고
    • Deciphering the genesis and fate of amyloid β-protein yields novel therapies for Alzheimer's disease
    • Selkoe D. J. (2002) Deciphering the genesis and fate of amyloid β-protein yields novel therapies for Alzheimer's disease. J. Clin. Invest. 110, 1375-1381.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1375-1381
    • Selkoe, D.J.1
  • 34
    • 0035875975 scopus 로고    scopus 로고
    • Differential regulation of cell migration and cell cycle progression by FAK complexes with Src, PI3K, Grb7 and Grb2 in focal contacts
    • Shen T. L. and Guan J. L. (2001) Differential regulation of cell migration and cell cycle progression by FAK complexes with Src, PI3K, Grb7 and Grb2 in focal contacts. FEBS Lett. 499, 176-181.
    • (2001) FEBS Lett. , vol.499 , pp. 176-181
    • Shen, T.L.1    Guan, J.L.2
  • 35
    • 0029935765 scopus 로고    scopus 로고
    • Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons
    • Simons M., De Strooper B., Multhaup G., Tienari P. J., Dotti C. G. and Beyreuther K. (1996) Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons. J. Neurosci. 16, 899-908.
    • (1996) J. Neurosci. , vol.16 , pp. 899-908
    • Simons, M.1    De Strooper, B.2    Multhaup, G.3    Tienari, P.J.4    Dotti, C.G.5    Beyreuther, K.6
  • 36
    • 0033518251 scopus 로고    scopus 로고
    • Purification and cloning of amyloid precursor protein β-secretase from human brain
    • Sinha S., Anderson J. P., Barbour R. et al. (1999) Purification and cloning of amyloid precursor protein β-secretase from human brain. Nature 402, 537-540.
    • (1999) Nature , vol.402 , pp. 537-540
    • Sinha, S.1    Anderson, J.P.2    Barbour, R.3
  • 38
    • 0037053281 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the β-amyloid precursor protein cytoplasmic tail promotes interaction with Shc
    • Tarr P. E., Roncarati R., Pelicci G., Pelicci P. G. and D'Adamio L. (2002b) Tyrosine phosphorylation of the β-amyloid precursor protein cytoplasmic tail promotes interaction with Shc. J. Biol. Chem. 277, 16798-16804.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16798-16804
    • Tarr, P.E.1    Roncarati, R.2    Pelicci, G.3    Pelicci, P.G.4    D'Adamio, L.5
  • 39
    • 85047695800 scopus 로고    scopus 로고
    • A p53-p66Shc signaling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis
    • Trinei M., Giorgio M., Cicalese A. et al. (2002) A p53-p66Shc signaling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. Oncogene 21, 3872-3878.
    • (2002) Oncogene , vol.21 , pp. 3872-3878
    • Trinei, M.1    Giorgio, M.2    Cicalese, A.3
  • 40
    • 0033595706 scopus 로고    scopus 로고
    • Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
    • Vassar R., Bennett B. D., Babu-Khan S. et al. (1999) Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286, 735-741.
    • (1999) Science , vol.286 , pp. 735-741
    • Vassar, R.1    Bennett, B.D.2    Babu-Khan, S.3
  • 42
    • 0033518264 scopus 로고    scopus 로고
    • Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity
    • Yan R., Bienkowski M. J., Shuck M. E. et al. (1999) Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity. Nature 402, 533-537.
    • (1999) Nature , vol.402 , pp. 533-537
    • Yan, R.1    Bienkowski, M.J.2    Shuck, M.E.3
  • 45
    • 0030894021 scopus 로고    scopus 로고
    • Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's β-amyloid precursor proteins
    • Zambrano N., Buxbaum J. D., Minopoli G. et al. (1997) Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's β-amyloid precursor proteins. J. Biol. Chem. 272, 6399-6405.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6399-6405
    • Zambrano, N.1    Buxbaum, J.D.2    Minopoli, G.3
  • 46
    • 0035827587 scopus 로고    scopus 로고
    • The β-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene
    • Zambrano N., Bruni P., Minopoli G., Mosca R., Molino D., Russo C., Schettini G., Sudol M. and Russo T. (2001) The β-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene. J. Biol. Chem. 276, 19787-19792.
    • (2001) J. Biol. Chem. , vol.276 , pp. 19787-19792
    • Zambrano, N.1    Bruni, P.2    Minopoli, G.3    Mosca, R.4    Molino, D.5    Russo, C.6    Schettini, G.7    Sudol, M.8    Russo, T.9
  • 47
    • 0037378901 scopus 로고    scopus 로고
    • The transcriptional cctivity of the APP intracellular domain-Fe65 complex is inhibited by activation of the NF-κB pathway
    • Zhao Q. and Lee F. S. (2003) The transcriptional cctivity of the APP intracellular domain-Fe65 complex is inhibited by activation of the NF-κB pathway. Biochemistry 42, 3627-3634.
    • (2003) Biochemistry , vol.42 , pp. 3627-3634
    • Zhao, Q.1    Lee, F.S.2
  • 48
    • 2942586693 scopus 로고    scopus 로고
    • GRB2 interaction with the tyrosine-phosphorylated tail of a AbPP is mediated by its SH2 domain
    • Epub 30 March 2004
    • Zhou D., Noviello C., D'Ambrosio C., Scaloni A. and D'Adamio L. (2004) GRB2 interaction with the tyrosine-phosphorylated tail of a AbPP is mediated by its SH2 domain. J. Biol Chem. 279, 25374-25380, Epub 30 March 2004.
    • (2004) J. Biol. Chem. , vol.279 , pp. 25374-25380
    • Zhou, D.1    Noviello, C.2    D'Ambrosio, C.3    Scaloni, A.4    D'Adamio, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.