Juvenile myelomonocytic leukemia presenting with features of hemophagocytic lymphohistiocytosis in association with neurofibromatosis and juvenile xanthogranulomas

Journal of Pediatric Hematology/Oncology

Volumn 26, Issue 9, 2004, Pages 591-595

  Shin, Helen T ^a   Harris, Michael B ^b   Orlow, Seth J ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HACKENSACK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Hemophagocytic lymphohistiocytosis; Juvenile myelomonocytic leukemia; Juvenile xanthogranuloma; Neurofibromatosis 1

Indexed keywords

CYCLOSPORIN; CYTARABINE; DEXAMETHASONE; ENALAPRIL; ETOPOSIDE; FLUDARABINE; MEGESTROL; RANITIDINE; VANCOMYCIN;

ANEMIA; ARTICLE; BLOOD TRANSFUSION; BONE MARROW BIOPSY; CAFE AU LAIT SPOT; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CATHETER INFECTION; CAUSE OF DEATH; CHROMOSOME ANALYSIS; CHROMOSOME TRANSLOCATION 3; CHROMOSOME TRANSLOCATION 8; CLINICAL FEATURE; DISEASE ASSOCIATION; DISEASE COURSE; ENDOSCOPY; FLOW CYTOMETRY; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HEPATOMEGALY; HISTIOCYTE; HISTOPATHOLOGY; HUMAN; HYPERTENSION; JUVENILE XANTHOGRANULOMA; MALE; MYELOMONOCYTIC LEUKEMIA; NEUROFIBROMATOSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT REFERRAL; PHYSICAL EXAMINATION; PRESCHOOL CHILD; PRIORITY JOURNAL; SPLENOMEGALY; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA;

BONE MARROW; FATAL OUTCOME; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; INFANT; LEUKEMIA, MYELOMONOCYTIC, CHRONIC; MALE; NEUROFIBROMATOSIS 1; XANTHOGRANULOMA, JUVENILE;

EID: 4544298220     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mph.0000135282.39550.99     Document Type: Article

References (25)

1. Royer P, Blondet C, Guihard J. Xantholeucemie du nourrisson et neuro-fibromatose de Recklinghausen. Ann Pediatr. 1958;24:1504-1513.
2. Morier P, Merot Y, Paccaud D, et al. Juvenile chronic granulocytic leukemia, juvenile xanthogranulomas, and neurofibromatosis. J Am Acad Dermatol. 1990;22:962-965.
3. Zvulunov A, Barak Y, Metzker D. Juvenile xanthogranuloma, neurofibromatosis, and juvenile chronic myelogenous leukemia. Arch Dermatol. 1995;131:904-908.
4. Jensen NE, Sabharwal S, Walker AE. Naevoxanthoendothelioma and neurofibromatosis. Br J Dermatol. 1971;85:326-330.
5. Newell GB, Stone OJ, Mullins JF. Juvenile xanthogranuloma and neuro-fibromatosis. Arch Dermatol. 1973;107:262.
6. Ackerman CD, Cohen BA. Juvenile xanthogranuloma and neurofibromatosis. Pediatr Dermatol. 1991;8:339-340.
7. Cooper PH, Frierson HF, Kayne AL, et al. Association of juvenile xanthogranuloma with juvenile myeloid leukemia. Arch Dermatol. 1984;120: 371-375.
8. Reich SD, Wiernik PH. Von Recklinghausen neurofibromatosis and acute leukemia. Am J Dis Child. 1976;130:888-889.
9. Bader JZ, Miller RW. Neurofibromatosis and childhood leukemia. J Pediatr. 1978;92:925-929.
10. Renter JI, Blinder G, Ost A. Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte Society. Semin Oncol. 1991;18:29-33.
11. Imashuku S, Hibi S, Kuriyama K, et al. Hemophagocytosis by leukemic blasts in a case of acute megakaryoblastic leukemia with t(16;21)(p11;q22). Int J Hematol. 1999;70:36-39.
12. Imashuku S, Hibi S, Sako M, et al. Hemophagocytosis by leukemic blasts in 7 acute myeloid leukemia cases with t(16;21)(p11;q22): common morphologic characteristics for this type of leukemia. Cancer. 2000;88:1970-1975.
13. Lai JL, Zandecki M, Jouet JP, et al. Three cases of translocation (8;16)(p11;p13) observed in acute myelomonocytic leukemia: a new specific subgroup? Cancer Genet Cytogenet. 1987;27:101-109.
14. Suzuki T, Mugishima H, Yamada A, et al. Development of acute lymphoblastic leukemia following hemophagocytic lymphohistiocytosis: is it secondary leukemia? Int J Hematol. 1999;70:58-59.
15. Freyer DR, Kennedy R, Bostrom BC, et al. Juvenile xanthogranuloma: forms of systemic disease and their clinical implications. J Pediatr. 1996; 129:227-237.
16. de Graaf JH, Timens W, Tamminga RY, et al. Deep juvenile xanthogranuloma: a lesion related to dermal indeterminate cells. Hum Pathol. 1992; 23:905-910.
17. Favara BE, Feller AC. Contemporary classification of histiocytic disorders. The WHO Committee on Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society. Med Pediatr Oncol. 1997;29:157-166.
18. Arico M, Janka G, Fischer A, et al. Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry. FHL Study Group of the Histiocyte Society. Leukemia. 1996;10:197-203.
19. Reiner AP, Spivak JL. Hematophagic histiocytosis. A report of 23 new patients and a review of the literature. Medicine. 1988;67:369-388.
20. Kumar M, Boggino H, Hudnall SD, et al. Acute myeloid leukemia associated with hemophagocytic syndrome and t(4;7)(q21;q36). Cancer Genet Cytogenet. 2000;122:26-29.
21. Heim S, Avanzi G, Billstrom R, et al. A new specific chromosomal rearrangement, t(8;16) (p11;p13), in acute monocytic leukaemia. Br J Haematol. 1987;66:323-326.
22. Freedman MH, Estrov Z. Juvenile chronic myelogenous leukaemia and histiocytosis syndromes in children. Lancet. 1987;1:754.
23. Gutman DH, Gurney JG, Shannon KM. Juvenile xanthogranuloma, neurofibromatosis 1, and juvenile chronic myeloid leukemia. Arch Dermatol. 1996;132:1390-1391.
24. Side LE, Emanuel PD, Taylor B, et al. Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1. Blood. 1998;92:267-272.
25. Shannon KM, O'Connell P, Martin GA, et al. Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders. N Engl J Med. 1994;330:597-601.