Pancreatitis in childhood

Current Gastroenterology Reports

Volumn 6, Issue 3, 2004, Pages 240-246

  Lowe, Mark E ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; INFUSION FLUID; PROTEIN SPINK1; REGULATOR PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRYPSINOGEN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CFTR PROTEIN, HUMAN; SPINK1 PROTEIN, HUMAN; TRYPSIN;

ABDOMINAL PAIN; ACUTE PANCREATITIS; ARCHITECTURE; CHILDHOOD DISEASE; CHRONIC PAIN; CHRONIC PANCREATITIS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC CODE; GENETIC IDENTIFICATION; GENETIC RISK; HUMAN; PANCREAS FUNCTION; PANCREATITIS; PATHOPHYSIOLOGY; PREVALENCE; REVIEW; ACUTE DISEASE; ANIMAL; CHILD; CHRONIC DISEASE; GENETICS; METABOLISM; PHYSIOLOGY;

ACUTE DISEASE; ANIMALS; CARRIER PROTEINS; CHILD; CHRONIC DISEASE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; PANCREATITIS; TRYPSIN; TRYPSINOGEN;

EID: 4544286191     PISSN: 15228037     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11894-004-0014-5     Document Type: Review

References (43)

1. Werlin SL, Kugathasan S, Frautschy BC: Pancreatitis in children. J Pediatr Gastroenterol Nutr 2003, 37: 591-595.
2. Lopez MJ: The changing incidence of acute pancreatitis in children: a single-institution perspective. J Pediatr 2002, 140: 622-624.
3. DeBanto JR, Goday PS, Pedroso MR, et al.: Acute pancreatitis in children. Am J Gastroenterol 2002, 97: 1726-1731.
4. Steer ML: Frank Brooks Memorial Lecture: The early intraacinar cell events which occur during acute pancreatitis. Pancreas 1998, 17: 31-37.
5. Sakorafas GH, Tsiotou AG: Etiology and pathogenesis of acute pancreatitis: current concepts. J Clin Gastroenterol 2000, 30: 343-356.
6. Choi BH, Lim YJ, Yoon CH, et al.: Acute pancreatitis associated with biliary disease in children. J Gastroenterol Hepatol 2003, 18: 915-921.
7. Otani T, Chepilko SM, Grendell JH, et al.: Codistribution of TAP and the granule membrane protein GRAMP-92 in rat caerulein-induced pancreatitis. Am J Physiol 1998, 275: G999-G1009.
8. Cavallini G, Frulloni L: Antiproteasic agents in the prevention of post-ERCP pancreatitis: rationale for use and clinical results. JOP 2003, 4: 75-82.
9. Whitcomb DC: Genetic predispositions to acute and chronic pancreatitis. Med Clin North Am 2000, 84: 531-547.
10. Frossard JL, Past CM: Experimental acute pancreatitis: new insights into the pathophysiology. Front Biosci 2002, 7: 275-287.
11. Halangk W, Lerch MM, Brandt-Nedelev B, et al.: Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J Clin Invest 2000, 106: 773-781.
12. Schneider A, Whitcomb DC: Hereditary pancreatitis: a model for inflammatory diseases of the pancreas. Best Pract Res Clin Gastroenterol 2002, 16: 347-363.
13. Whitcomb DC, Gorry MC, Preston RA, et al.: Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996, 14: 141-145.
14. Etemad B, Whitcomb DC: Chronic pancreatitis: diagnosis, classification, and new genetic developments. Gastroenterology 2001, 120: 682-707.
15. Kukor Z, Toth M, Pal G, et al.: Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation. J Biol Chem 2002, 277: 6111-6117.
16. Sahin-Toth M: Human cationic trypsinogen: role of Asn-21 in zymogen activation and implications in hereditary pancreatitis. J Biol Chem 2000, 275: 22750-22755.
17. Sanfey H, Sarr MG, Bulkley GB, et al.: Oxygen-derived free radicals and acute pancreatitis: a review. Acta Physiol Scand Suppl 1986, 548: 109-118.
18. Guice KS, Miller DE, Oldham KT, et al.: Superoxide dismutase and catalase: a possible role in established pancreatitis. Am J Surg 1986, 151: 163-169.
19. Anderson MC, Schoenfeld FB, Iams WB, et al.: Circulatory changes in acute pancreatitis. Surg Clin North Am 1967, 47: 127-140.
20. Demols A, Le Moine O, Desalle F, et al.: CD4(+)T cells play an important role in acute experimental pancreatitis in mice. Gastroenterology 2000, 118: 582-590.
21. Gloor B, Todd KE, Lane JS, et al.: Hepatic Kupffer cell blockade reduces mortality of acute hemorrhagic pancreatitis in mice. J Gastrointest Surg 1998, 2: 430-435.
22. Pezzilli R, Billi P, Beltrandi E, et al.: Impaired lymphocyte proliferation in human acute pancreatitis. Digestion 1997, 58: 431-436.
23. Bhatia M, Brady M, Shokuhi S, et al.: Inflammatory mediators in acute pancreatitis. J Pathol 2000, 190: 117-125.
24. Bhatia M, Neoptolemos JP, Slavin J: Inflammatory mediators as therapeutic targets in acute pancreatitis. Curr Opin Investig Drugs 2001, 2: 496-501.
25. Abou-Assi S, Craig K, O'Keefe SJ: Hypocaloric jejunal feeding is better than total parenteral nutrition in acute pancreatitis: results of a randomized comparative study. Am J Gastroenterol 2002, 97: 2255-2262.
26. Ranson JH: Etiological and prognostic factors in human acute pancreatitis: a review. Am J Gastroenterol 1982, 77: 633-638.
27. Blamey SL, Imrie CW, O'Neill J, et al.: Prognostic factors in acute pancreatitis. Gut 1984, 25: 1340-1346.
28. Knaus WA, Draper EA, Wagner DP, et al.: APACHE II: a severity of disease classification system. Crit Care Med 1985, 13: 818-829.
29. Whitcomb DC: Hereditary pancreatitis: new insights into acute and chronic pancreatitis. Gut 1999, 45: 317-322.
30. Applebaum-Shapiro SE, Finch R, Pfutzer RH, et al.: Hereditary pancreatitis in North America: the Pittsburgh-Midwest Multi-Center Pancreatic Study Group Study. Pancreatology 2001, 1: 439-443.
31. Witt H, Luck W, Hennies HC, et al.: Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000, 25: 213-216.
32. Naruse S, Kitagawa M, Ishiguro H, et al.: Cystic fibrosis and related diseases of the pancreas. Best Pract Res Clin Gastroenterol 2002, 16: 511-526.
33. Noone PG, Zhou Z, Silverman LM, et al.: Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations. Gastroenterology 2001, 121: 1310-1319.
34. Sharer N, Schwarz M, Malone G, et al.: Mutations of the cystic fibrosis gene in patients with chronic pancreatitis. N Engl J Med 1998, 339: 645-652.
35. Cohn JA, Bornstein JD, Jowell PS: Cystic fibrosis mutations and genetic predisposition to idiopathic chronic pancreatitis. Med Clin North Am 2000, 84: 621-631.
36. Whitcomb DC: Value of genetic testing in management of pancreatitis. Gut 2004, in press.
37. Ellis I, Lerch MM, Whitcomb DC: Genetic testing for hereditary pancreatitis: guidelines for indications, counselling, consent and privacy issues. Pancreatology 2001, 1: 405-415.
38. Applebaum-Shapiro SE, Peters JA, O'Connell JA, et al.: Motivations and concerns of patients with access to genetic testing for hereditary pancreatitis. Am J Gastroenterol 2001, 96: 1610-1617.
39. Applebaum SE, Kant JA, Whitcomb DC, et al.: Genetic testing. Counseling, laboratory, and regulatory issues and the EUROPAC protocol for ethical research in multicenter studies of inherited pancreatic diseases. Med Clin North Am 2000, 84: 575-588.
40. Lowenfels AB, Maisonneuve P, Whitcomb DC, et al.: Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis. JAMA 2001, 286: 169-170.
41. Whitcomb DC: Motion-genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments for the motion. Can J Gastroenterol 2003, 17: 47-52.
42. Cohn JA: Motion-genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments against the motion. Can J Gastroenterol 2003, 17: 53-55.
43. Pfutzer RH, Barmada MM, Brunskill AP, et al.: SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis. Gastroenterology 2000, 119: 615-623.