Family cancer histories predictive of a high risk of hereditary non-polyposis colorectal cancer associate significantly with a genomic rearrangement in hMSH2 or hMLH1

Clinical Genetics

Volumn 66, Issue 3, 2004, Pages 183-188

  Ainsworth, Peter J ^a   Koscinski, D ^a   Fraser, B P ^a   Stuart, J A ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Cancer; Colon; Familial; Gene; HNPCC; MLPA; Mutation; Rearrangement; Risk

Indexed keywords

DNA; PROTEIN MLH1; PROTEIN MSH2;

ARTICLE; CALCULATION; CANADA; CANCER RISK; COLORECTAL CANCER; COMPUTER AIDED DESIGN; COMPUTER PROGRAM; DNA ISOLATION; FAMILIAL CANCER; FAMILY HISTORY; GENE AMPLIFICATION; GENE DELETION; GENE REARRANGEMENT; GERM LINE; HIGH RISK POPULATION; HUMAN; LEUKOCYTE; MAJOR CLINICAL STUDY; MISMATCH REPAIR; MUTATIONAL ANALYSIS; PEDIGREE; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT;

CARRIER PROTEINS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE REARRANGEMENT; GENETIC SCREENING; GERM-LINE MUTATION; HUMANS; MOLECULAR PROBES; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; ONTARIO; PEDIGREE; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; RISK ASSESSMENT;

EID: 4544285279     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0009-9163.2004.00282.x     Document Type: Article

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