Synthesis and antibacterial evaluation of 1 β-methyl-2-(5-substituted heterocyclic carbamoyl)pyrrolidin-3-ylthio)carbapenem derivatives

Archiv der Pharmazie

Volumn 337, Issue 7, 2004, Pages 391-397

  Lee, Joo Shin ^a   Cho, Jung Hyuck ^a   Cho, Heeyeong ^b   Oh, Chang Hyun ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Methylcarbapenem; Antibacterial activity; Substituent effect

Indexed keywords

6 (1 HYDROXYETHYL) 2 [5 (N THIAZOLIDIN 2 YLMETHYL)CARBAMOYLPYRROLIDIN 3 YLTHIOL] 1 METHYLCARBAPEN 2 EM 3 CARBOXYLIC ACID; CARBAPENEM DERIVATIVE; IMIPENEM; MEROPENEM; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; CARBAPENEMS; COLONY COUNT, MICROBIAL; DRUG DESIGN; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; PYRROLIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4544281803     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.200400867     Document Type: Article

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