Current role of hepatic artery infusion and isolated liver perfusion for the treatment of colorectal cancer liver metastases

Cancer Journal

Volumn 10, Issue 2, 2004, Pages 128-138

  Elaraj, Dina M ^a,b   Alexander, H Richard ^a,b  

^a National Institutes of Health ^*

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Colorectal neoplasms; Hyperthermia; Isolation perfusion; Liver; Neoplasm metastases; Perfusion; Regional

Indexed keywords

ANTINEOPLASTIC AGENT;

CANCER CHEMOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; COLORECTAL CANCER; HEPATIC ARTERY; HUMAN; ISOLATED LIVER; LIVER METASTASIS; LIVER PERFUSION; PRIORITY JOURNAL; REVIEW; ADJUVANT CHEMOTHERAPY; COLORECTAL TUMOR; INFUSION PUMP; INTRAARTERIAL DRUG ADMINISTRATION; LIVER TUMOR; METASTASIS; METHODOLOGY; PATHOLOGY; REGIONAL PERFUSION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; CHEMOTHERAPY, CANCER, REGIONAL PERFUSION; COLORECTAL NEOPLASMS; HEPATIC ARTERY; HUMANS; INFUSION PUMPS, IMPLANTABLE; INFUSIONS, INTRA-ARTERIAL; LIVER NEOPLASMS;

EID: 4544276349     PISSN: 15289117     EISSN: 1540336X     Source Type: Journal    
DOI: 10.1097/00130404-200403000-00008     Document Type: Review

References (42)

1. Jemal A, Murray T, Samuels A et al. Cancer statistics, 2003. CA Cancer J Clin 2003;53:5-26.
2. Scheele J, Stangl R, Altendorf-Hofmann A. Hepatic metastases from colorectal carcinoma: impact of surgical resection on the natural history. Br J Surg 1990;77:1241-1246.
3. Weiss L, Grundman E, Torhurst J et al. Hematogenous metastatic patterns in colonic carcinoma: an analysis of 1541 necropsies. J Pathol 1986;150:195-203.
4. Bengmark S, Hafstrom L. The natural history of primary and secondary malignant tumors of the liver. I: The prognosis for patients with hepatic metastases from colonic and rectal carcinoma by laparotomy. Cancer 1969;23:198-202.
5. Jaffe BM, Donegan WL, Watson F et al. Factors influencing survival in patients with untreated hepatic metastases. Surg Gynecol Obstet 1968;127:1-11.
6. Saltz LB, Cox JV, Blanke C et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000;343:905-914.
7. Fong Y, Fortner J, Sun RL et al. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer. Ann Surg 1999;230:309-321.
8. Breedis C, Young G. The blood supply of neoplasms in the liver. Am J Pathol 1954;969:985.
9. Lin G, Lunderquist A, Hägerstrand I et al. Postmortem examination of the blood supply and vascular pattern of small liver metastases in man. Surgery 1984;96:517-526.
10. Fong Y, Cohen AM, Fortner JG et al. Liver resection for colorectal metastases. J Clin Oncol 1997;15:938-946.
11. Hughes KS, Simon R, Songhorabodi S et al. Resection of the liver for colorectal carcinoma metastases: a multi-institutional study of patterns of recurrence. Surgery 1986;100:278-284.
12. Ensminger WD, Rosowsky A, Raso V et al. A clinical-pharmacologic evaluation of hepatic arterial infusions of 5-fluoro-2′-deoxyuridine and 5-fluorouracil. Cancer Res 1978;38:3784-3792.
13. Aigner KR, Walther H, Link KH. Isolated liver perfusion with MMC/5-FU: surgical technique, pharmacokinetics, clinical results. Contr Oncol 1988;29:229-246.
14. Bartlett DL, Libutti SK, Figg WD et al. Isolated hepatic perfusion for unresectable hepatic metastases from colorectal cancer. Surgery 2001;129:176-187.
15. Harmantas A, Rothstein LE, Langer B. Regional versus systemic chemotherapy in the treatment of colorectal carcinoma metastatic to the liver: is there a survival difference? Meta-analysis of the published literature. Cancer 1996;78:1639-1645.
16. Lorenz M, Muller HH. Randomized, multicenter trial of fluorouracil plus leucovorin administered either via hepatic arterial or intravenous infusion versus fluorodeoxyuridine administered via hepatic arterial infusion in patients with nonresectable liver metastases from colorectal carcinoma. J Clin Oncol 2000;18:243-254.
17. Meta-Analysis Group in Cancer. Reappraisal of Hepatic Arterial Infusion in the Treatment of nonresectable liver metastases from colorectal cancer. J Natl Cancer Inst 1996;88:252-258.
18. Schwemmle K, Link KH, Rieck B. Rationale and indications for perfusion in liver tumors: current data. World J Surg 1987;11:534-540.
19. Kemeny MM. The surgical aspects of the totally implantable hepatic artery infusion pump. Arch Surg 2001;136:348-352.
20. Kerr DJ, McArdle CS, Ledermann J et al. Intrahepatic arterial versus intravenous fluorouracil and folinic acid for colorectal cancer liver metastases: a multicentre randomised trial. Lancet 2003;361:368-373.
21. Kemeny MM, Battifora H, Blayney DW et al. Sclerosing cholangitis after continuous hepatic artery infusion of FUDR. Ann Surg 1985;202:176-181.
22. Kemeny N, Conti JA, Cohen A et al. Phase II study of hepatic arterial floxuridine, leucovorin, and dexamethasone for unresectable liver metastases from colorectal carcinoma. J Clin Oncol 1994;12:2288-2295.
23. Lorenz M, Müller H-H, Schramm H et al. Randomized trial of surgery versus surgery followed by adjuvant hepatic arterial infusion with 5-fluorouracil and folinic acid for liver metastases of colorectal cancer. Ann Surg 1998;228:756-762.
24. Kemeny N, Huang Y, Cohen AM et al. Hepatic arterial infusion of chemotherapy after resection of hepatic metastases from colorectal cancer. N Engl J Med 1999;341:2039-2048.
25. Kemeny MM, Adak S, Gray B et al. Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy: an intergroup study. J Clin Oncol 2002;20:1499-1505.
26. Chang AE, Schneider PD, Sugarbaker PH et al. A prospective randomized trial of regional versus systemic continuous fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases. Ann Surg 1987;206:685-693.
27. Hohn DC, Stagg RJ, Friedman MA et al. A randomized trial of continuous intravenous versus hepatic intraarterial floxuridine in patients with colorectal cancer metastatic to the liver: the Northern California oncology group trial. J Clin Oncol 1989;7:1646-1654.
28. Kemeny N, Daly J, Reichman B et al. Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases from colorectal carcinoma. Ann Intern Med 1987;107:459-465.
29. Martin JK, O'Connel MJ, Wieand HS et al. Intra-arterial floxuridine vs systemic fluorouracil for hepatic metastases from colorectal cancer. Arch Surg 1990;125:1022-1027.
30. Allen-Mersh TG, Earlam S, Fordy C et al. Quality of life and survival with continuous hepatic-artery floxuridine infusion for colorectal liver metastases. Lancet 1994;344:1255-1260.
31. Kemeny MM, Goldberg D, Beatty JD et al. Results of a prospective randomized trial of continuous regional chemotherapy and hepatic resection as treatment of hepatic metastases from colorectal primaries. Cancer 1986;57:492-498.
32. Rougier P, LaPlanche A, Huguier M et al. Hepatic arterial infusion of floxuridine in patients with liver metastases from colorectal carcinoma: long-term results of a prospective randomized trial. J Clin Oncol 1992;10:1112-1118.
33. Wagman LD, Kemeny MM, Leong L et al. A prospective, randomized evaluation of the treatment of colorectal cancer metastatic to the liver. J Clin Oncol 1990;8:1885-1893.
34. Kemeny N, Seiter K, Conti JA et al. Hepatic arterial floxuridine and leucovorin for unresectable liver metastases from colorectal carcinoma: new dose schedules and survival update. Cancer 1994;73:1134-1142.
35. Kemeny NE, Ron IG. Hepatic arterial chemotherapy in metastatic colorectal patients. Semin Oncol 1999;26:524-535.
36. Ausman RK. Development of a technique for isolated perfusion of the liver. NY State J Med 1961;61:3393-3397.
37. Libutti SK, Bartlett DL, Fraker DL et al. Technique and results of hyperthermic isolated hepatic perfusion with tumor necrosis factor and melphalan for the treatment of unresectable hepatic malignancies. J Am Coll Surg 2000;191:519-530.
38. Alexander HR, Bartlett DL, Libutti SK et al. Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver. J Clin Oncol 1998;16:1479-1489.
39. Marinelli A, de Brauw LM, Beerman H et al. Isolated liver perfusion with mitomycin C in the treatment of colorectal cancer metastases confined to the liver. Jpn J Clin Oncol 1996;26:341-350.
40. Vahrmeijer AL, Van Dierendonck JH, Keizer HJ et al. Increased local cytostatic drug exposure by isolated hepatic perfusion: a phase I clinical and pharmacologic evaluation of treatment with high dose melphalan in patients with colorectal cancer confined to the liver. Br J Cancer 2000;82:1539-1546.
41. Alexander HR Jr, Libutti SK, Bartlett DL et al. Hepatic vascular isolation and perfusion for patients with progressive unresectable liver metastases from colorectal carcinoma refractory to previous systemic and regional chemotherapy. Cancer 2002;95:730-736.
42. de Gramont A, Figer A, Seymour M et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000;18:2938-2947.