Fibrin-filled scaffolds for bone-tissue engineering: An in vivo study

Journal of Biomedical Materials Research - Part A

Volumn 71, Issue 1, 2004, Pages 162-171

  Karp, Jeffrey M ^a,b   Sarraf, Feryal ^a,b   Shoichet, Molly S ^a,b   Davies, John E ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Biodegradable polymer; Composite; Matrix structure; Thrombin concentration; Wound healing

Indexed keywords

BONE; CELLS; ELECTROPHORESIS; GELS; PHYSIOLOGICAL MODELS; POLYMERIZATION; TISSUE;

FIBRIN-FILLED SCAFFOLDS; POLYACRYLAMIDE GELS; THROMBIN; TISSUE ENGINEERING;

BIOMEDICAL ENGINEERING;

FIBRIN; SEALANT;

ANIMAL TISSUE; ARTICLE; BONE TISSUE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS LINKING; DRILL; EXPERIMENTAL TEST; FEMUR; IMPLANT; IN VIVO STUDY; MORPHOMETRICS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERIZATION; PROTEIN DEGRADATION; RAT; STATISTICAL SIGNIFICANCE; STRUCTURE ANALYSIS; TISSUE ENGINEERING; WOUND HEALING;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE REGENERATION; FEMUR; FIBRIN; LACTIC ACID; MALE; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; POLYGLYCOLIC ACID; POLYMERS; RANDOM ALLOCATION; RATS; RATS, INBRED STRAINS; THROMBIN; TISSUE ENGINEERING; WOUND HEALING;

EID: 4544274991     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.a.30147     Document Type: Article

References (47)

1. Tajima M, Kuwahara S, Hirakawa S, Matsumoto K. Bone grafts using fibrin glue for posterolateral spinal fusion and total hip replacement with central migration. In: Redl H, Schlag G, editors. Fibrin sealing in surgical and nonsurgical fields. New York: Springer-Verlag; 1994. p 29-36.
2. Sielewicz M, Scholz J. Fibrin adhesive cancellous plasty in treating the dysplastic acetabulum in total joint replacement surgery: case report. In: Redl H, Schlag G, editors. Fibrin sealing in surgical and nonsurgical fields. New York: Springer-Verlag; 1994. p 37-43.
3. Marchetti N, Lisanti M, Scaglione M, Punzi G, Gabellieri P, Kufert J. Fibrin sealant in the treatment of infections in orthopedics. In: Redl H, Schlag G, editors. Fibrin sealing in surgical and nonsurgical fields. New York: Springer-Verlag; 1994. p 121-129.
4. Ferrari Parabita G, Derada Troletti GC, Cattaneo R, Ferrari Parabita S. The use of human fibrin glue in reconstructive maxillofacial surgery. In: Redl H, Schlag G, editors. Fibrin sealing in surgical and nonsurgical fields. New York: Springer-Verlag; 1994. p 139-146.
5. Schlag G, Redl H. Fibrin sealant in orthopedic surgery. Clin Orthop 1988;227:269-285.
6. Lasa CJ, Hollinger J, Drohan W, MacPhee MJ. Bone induction by demineralized bone powder and partially purified osteogenin using a fibrin-sealant carrier. In: Saltz R, Sierra DH, editors. Surgical adhesives and sealants: current technology and applications. Lancaster, PA: Technomic; 1996. p 135-143.
7. Urban K, Povysil C, Spelda S. [Effect of fibrin on osseointegration of bioactive glass-ceramic materials: experimental study]. Acta Chir Orthop Traumatol Cech 2001;68(3):168-175.
8. Oberg S, Kahnberg KE. Combined use of hydroxy-apatite and Tisseel in experimental bone defects in the rabbit. Swed Dent J 1993;17(4):147-153.
9. Cunin G, Boissonnet H, Petite H, Blanchat C, Guillemin G. Experimental vertebroplasty using osteoconductive granular material. Spine 2000;25(9):1070-1076.
10. Huang Q, Goh JC, Hutmacher DW, Lee EH. In vivo mesenchymal cell recruitment by a scaffold loaded with transforming growth factor beta1 and the potential for in situ chondrogenesis. Tissue Eng 2002;8(3):469-482.
11. Kawamura M, Urist MR. Human fibrin is a physiologic delivery system for bone morphogenetic protein. Clin Orthop 1988(235):302-310.
12. Yamada Y, Seong Boo J, Ozawa R, Nagasaka T, Okazaki Y, Hata K, Ueda M. Bone regeneration following injection of mesenchymal stem cells and fibrin glue with a biodegradable scaffold. J Craniomaxillofac Surg 2003;31(1):27-33.
13. van Susante JL, Buma P, Schuman L, Homminga GN, van den Berg WB, Veth RP. Resurfacing potential of heterologous chondrocytes suspended in fibrin glue in large full-thickness defects of femoral articular cartilage: an experimental study in the goat. Biomaterials 1999;20(13):1167-1175.
14. Bach AD, Bannasch H, Galla TJ, Bittner KM, Stark GB. Fibrin glue as matrix for cultured autologous urothelial cells in urethral reconstruction. Tissue Eng 2001;7(1):45-53.
15. Gurevich O, Vexler A, Marx G, Prigozhina T, Levdansky L, Slavin S, Shimeliovich I, Gorodetsky R. Fibrin microbeads for isolating and growing bone marrow-derived progenitor cells capable of forming bone tissue. Tissue Eng 2002;8(4):661-672.
16. Perka C, Schultz O, Spitzer RS, Lindenhayn K, Burmester GR, Sittinger M. Segmental bone repair by tissue-engineered peri-osteal cell transplants with bioresorbable fleece and fibrin scaffolds in rabbits. Biomaterials 2000;21(11):1145-1153.
17. Schantz JT, Teoh SH, Lim TC, Endres M, Lam CX, Hutmacher DW. Repair of calvarial defects with customized tissue-engineered bone grafts. I. Evaluation of osteogenesis in a three-dimensional culture system. Tissue Eng 2003;9(Suppl 1):S113-S126.
18. Schantz JT, Hutmacher DW, Lam CX, Brinkmann M, Wong KM, Lim TC, Chou N, Guldberg RE, Teoh SH. Repair of calvarial defects with customised tissue-engineered bone grafts. II. Evaluation of cellular efficiency and efficacy in vivo. Tissue Eng 2003;9(Suppl 1):S127-S139.
19. Senior RM, Skogen WF, Griffin GL, Wilner GD. Effects of fibrinogen derivatives upon the inflammatory response. Studies with human fibrinopeptide B. J Clin Invest 1986;77(3):1014-1019.
20. Leavell KJ, Peterson MW, Gross TJ. The role of fibrin degradation products in neutrophil recruitment to the lung. Am J Respir Cell Mol Biol 1996;14(1):53-60.
21. Thompson WD, Smith EB, Stirk CM, Marshall FI, Stout AJ, Kocchar A. Angiogenic activity of fibrin degradation products is located in fibrin fragment E. J Pathol 1992;168(1):47-53.
22. Albrektsson T, Bach A, Edshage S, Jonsson A. Fibrin adhesive system (FAS) influence on bone healing rate: a microradiographical evaluation using the bone growth chamber. Acta Orthop Scand 1982;53(5):757-763.
23. Schwarz N. The role of fibrin sealant in osteoinduction. Ann Chir Gynaecol Suppl 1993;207:63-68.
24. Bosch P, Lintner F, Arbes H, Brand G. Experimental investigations of the effect of the fibrin adhesive on the Kiel heterologous bone graft. Arch Orthop Trauma Surg 1980;96(3):177-185.
25. Carmagnola D, Berglundh T, Lindhe J. The effect of a fibrin glue on the integration of Bio-Oss with bone tissue. An experimental study in Labrador dogs. J Clin Periodontol 2002;29(5):377-383.
26. Abiraman S, Varma HK, Umashankar PR, John A. Fibrin glue as an osteoinductive protein in a mouse model. Biomaterials 2002;23(14):3023-3031.
27. Kania RE, Meunier A, Hamadouche M, Sedel L, Petite H. Addition of fibrin sealant to ceramic promotes bone repair: long-term study in rabbit femoral defect model. J Biomed Mater Res 1998;43(1):38-45.
28. Brittberg M, Sjogren-Jansson E, Lindahl A, Peterson L. Influence of fibrin sealant (Tisseel) on osteochondral defect repair in the rabbit knee. Biomaterials 1997;18(3):235-242.
29. Jackson MR. Fibrin sealants in surgical practice: an overview. Am J Surg 2001;182(2 Suppl):1S-7S.
30. Ryan EA, Mockros LF, Weisel JW, Lorand L. Structural origins of fibrin clot rheology. Biophys J 1999;77(5):2813-2826.
31. Nehls V, Herrmann R. The configuration of fibrin clots determines capillary morphogenesis and endothelial cell migration. Microvasc Res 1996;51(3):347-364.
32. Amrani DL, Diorio JP, Delmotte Y. Wound healing. Role of commercial fibrin sealants. Ann NY Acad Sci 2001;936:566-579.
33. Carr ME. Fibrin formed in plasma is composed of fibers more massive than those formed from purified fibrinogen. Thromb Haemost 1988;59(3):535-539.
34. Karp JM, Rzeszutek K, Shoichet MS, Davies JE. Fabrication of precise cylindrical three-dimensional tissue engineering scaffolds for in vitro and in vivo bone engineering applications. J Craniofac Surg 2003;14(3):317-323.
35. Naito M, Nomura H, Iguchi A, Thompson WD, Smith EB. Effect of crosslinking by factor XIIIa on the migration of vascular smooth muscle cells into fibrin gels. Thromb Res 1998; 90(3):111-116.
36. Brown LF, Lanir N, McDonagh J, Tognazzi K, Dvorak AM, Dvorak HF. Fibroblast migration in fibrin gel matrices. Am J Pathol 1993;142(1):273-283.
37. Junquiera LC, Junqueira LC, Brentani RR. A simple and sensitive method for the quantitative estimation of collagen. Anal Biochem 1979;94(1):96-99.
38. Puchtler H, Waldrop FS, Valentine LS. Polarization microscopic studies of connective tissue stained with picro-sirius red FBA. Beitr Pathol 1973;150(2):174-187.
39. Sakata Y, Aoki N. Cross-linking of alpha 2-plasmin inhibitor to fibrin by fibrin-stabilizing factor. J Clin Invest 1980;65(2):290-297.
40. Knox P, Crooks S, Scaife MC, Patel S. Role of plasminogen, plasmin, and plasminogen activators in the migration of fibroblasts into plasma clots. J Cell Physiol 1987;132(3):501-508.
41. Diamond SL, Anand S. Inner clot diffusion and permeation during fibrinolysis. Biophys J 1993;65(6):2622-2643.
42. van Kooyk Y, Figdor CG. Avidity regulation of integrins: the driving force in leukocyte adhesion. Curr Opin Cell Biol 2000; 12(5):542-547.
43. Ciano PS, Colvin RB, Dvorak AM, McDonagh J, Dvorak HF. Macrophage migration in fibrin gel matrices. Lab Invest 1986; 54(1):62-70.
44. Hanson AJ, Quinn MT. Effect of fibrin sealant composition on human neutrophil chemotaxis. J Biomed Mater Res 2002;61(3):474-481.
45. Herbert CB, Nagaswami C, Bittner GD, Hubbell JA, Weisel JW. Effects of fibrin micromorphology on neurite growth from dorsal root ganglia cultured in three-dimensional fibrin gels. J Biomed Mater Res 1998;40(4):551-559.
46. Krishnan LK, Vijayan Lal A, Uma Shankar PR, Mohanty M. Fibrinolysis inhibitors adversely affect remodeling of tissues sealed with fibrin glue. Biomaterials 2003;24(2):321-327.
47. Lutolf MP, Weber FE, Schmoekel HG, Schense JC, Kohler T, Muller R, Hubbell JA. Repair of bone defects using synthetic mimetics of collagenous extracellular matrices. Nat Biotechnol 2003;21(5):513-518.