Is normal β-hCG regression curve helpful in the diagnosis of persistent trophoblastic disease?

International Journal of Gynecological Cancer

Volumn 14, Issue 5, 2004, Pages 980-983

  Behtash, N ^a   Ghaemmaghami, F ^a   Honar, H ^a   Riazi, K ^a   Nori, A ^a   Modares, M ^a   Mousavi, A ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Human chorionic gonadotropin; Persistent trophoblastic disease; Regression curve

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT;

ADULT; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC ERROR; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; DISEASE MARKER; FEMALE; FOLLOW UP; HORMONE BLOOD LEVEL; HUMAN; HYDATIDIFORM MOLE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; TROPHOBLASTIC TUMOR;

ADULT; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; DIAGNOSIS, DIFFERENTIAL; FEMALE; GESTATIONAL TROPHOBLASTIC NEOPLASMS; HUMANS; HYDATIDIFORM MOLE; IRAN; PREGNANCY; REFERENCE VALUES; REGRESSION ANALYSIS; TUMOR MARKERS, BIOLOGICAL; UTERINE NEOPLASMS;

EID: 4544260815     PISSN: 1048891X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1048-891X.2004.14538.x     Document Type: Article

References (13)

1. Smith DB, O'Reilly SM, Newlands ES. Current approaches to diagnosis and treatment of gestational trophoblastic disease. Curr Opin Obstet Gynecol 1993;5:84-91.
2. Cunningham FG, Gant NF, Leveno KJ, Gilstrap LC III, Hauth JC, Wenstrom KD. Williams Obstetrics, 21st edn. New York: McGraw-Hill, 2001, 842.
3. Akazawa K, Nakamura T, Palesch Y. Power of log-rank test and regression model in clinical trial. Stat Med 1997;16:583-97.
4. Kohorn EI. The New FIGO 2000 staging and risk factor scoring system for GTD. Int J Gynecol Cancer 2001;11:73-7.
5. Shigematsu T, Kamura T, Saito T, Kaku T, Nakano H, Kinogawa N. Identification of persistent trophoblastic disease based on a human chorionic gonadotropin curve by means of a stepwise piecewise linear regression analysis after the evacuation of uneventful moles. Gynecol Oncol 1998;71:376-80.
6. Kohorn EI. Hydatidiform mole and gestational trophoblastic disease in southern Connecticut. Obstet Gynecol 1982;59:78-84.
7. Morrow CP, Kletzky OA, Disaia PJ, Townsend DE, Mishell DR, Nakamura RM. Clinical and laboratory correlates of molar pregnancy and trophoblastic disease. Am J Obstet Gynecol 1977;128:424-30.
8. Berek J. Novak Gynecology, 13th edn. Philadelphia, PA: Lippincott, Williams & Wilkins, 2002, 136.
9. Genest DR, Borde O, Berkowitz RS et al. A clinicopathologic study of 153 cases of complete H. mole. Obstet Gynecol 1991;78:402-9.
10. Feltmate CM, Batorfi J, Fulop V et al. Human chorionic gonadotropin follows up in patients with molar pregnancy: a time for re-evaluation. Obstet Gynecol 2003;101:732-6.
11. Yedema KA, Verheijen RH, Kenemans P et al. Identification of patients with persistent trophoblastic disease by means of a normal hCG curve. Am J Obstet Gynecol 1993;168:787-92.
12. Khanlian AS, Smith HO, Cole LA. Persistent low level of hCG: a premalignant GTD. Am J Obstet Gynecol 2003;188:1254-9.
13. Rob L, Robova H, Pluta M, Kulovany E et al. Regression of β-hCG in various types of molar pregnancies: clinical course and prognosis (article in Czech). Ceska Gynekol 2001;66:230-5 (Abstract).