Synthesis and radioiodination of some 9-aminoacridine derivatives

European Journal of Organic Chemistry

Volumn , Issue 17, 2004, Pages 3719-3725

  Ghirmai, Senait ^a   Mume, Eskender ^a   Henssen, Cecile ^a   Ghaneolhusseini, Hadi ^a   Lundqvist, Hans ^b   Tolmachev, Vladimir ^a,b   Sjöberg, Stefan ^a   Orlova, Anna ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

DNA; Intercalations; Iodine; Labeling; Radiochemistry; Tautomerism

Indexed keywords

2 (ACRIDIN 9 YLAMINO) 3 (4 HYDROXYPHENYL)PROPIONIC ACID; AMINOACRIDINE DERIVATIVE; DNA; HYDROXYL GROUP; IODINE 125; N [3 (ACRIDIN 9 YLAMINO)PROPYL] 3 (TRIMETHYLSTANNYL)BENZAMIDE; N [8 (ACRIDIN 9 YLAMINO)OCTYL] 3 (TRIMETHYLSTANNYL)BENZAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG PURIFICATION; DRUG SYNTHESIS; ISOTOPE LABELING; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOCHEMISTRY; RADIOIODINATION; ROOM TEMPERATURE; THIN LAYER CHROMATOGRAPHY;

EID: 4544239694     PISSN: 1434193X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ejoc.200400296     Document Type: Article

References (22)

1. A. W. McConnaughie, T. C. Jenkins, J. Med. Chem. 1995, 38, 3488-3501.
2. R. L. Wasters, K. G. Hofer, C. R. Harris, J. M. Smith, Curr. Top. Radiat. Res. Q. 1978, 12, 389-407.
3. T. L. Rosenbury, P. Barnet, C. Mays, Methods Enzymol. 1982, 82, 325-339.
4. D. J. Dupre, F. A. Robinson, J. Chem. Soc. 1945, 549-551.
5. H. Ghaneolhosseni, W. Tjarks, S. Sjöberg, Tetrahedron 1998, 54, 3877-3884.
6. N. H. Azizian, C. Eaborn, A. Pidcock, J. Organomet. Chem. 1981, 215, 49-58.
7. R. Faure, J. P. Galy, L. N. Gadi, J. Barbe, Magn. Reson. Chem. 1989, 27, 92-95.
8. J. Elguero, Z. Marzin, A. R. Katritzky, P. Linda, Adv. Heterocycl. Chem. 1976, Suppl. 1, 114.
9. J. Rak, K. Krzyminski, P. Skurski, L. Jozwiak, J. Blazejowski, J. Mol. Struct. 1999, 476, 45-55.
10. P. Skurski, J. Rak, J. Simons, J. Chem. Phys. 2001, 115, 11193-11199.
11. C. Chiang, J. Cheng, T. Chang, Proc. Natl. Sci. Counc. ROC(A) 1999, 23, 679-694.
12. J. Rak, P. Skurski, M. Gutowski, L. Jozwiak, J. Blazejowski, J. Phys. Chem. A. 1997, 101, 283-292.
13. J. Meszko, K. Krzyminski, A. Konitz, J. Blazejowki, Acta Crystallogr., Sect. E 2002, 58, 458-460.
14. J. Galy, R. Faure, J. Barbe, J. Elguero, Spectrosc. Lett. 1988, 21, 809-818.
15. M. Boyd, W. A. Denny, J. Med. Chem. 1990, 33, 2656-2659.
16. M. K. Dewanjee, Radioiodination: Theory, Practice, and Biomedical Application, Kluwer Academic Publishers, 1992.
17. P. K. Garg, S. Garg S, M. R. Zalutsky, Nucl. Med. Biol. 1993, 20, 379-387.
18. G. Vaidyanathan, M. R. Zalutsky, Bioconjugate Chem. 1990, 1, 387-393.
19. P. K. Garg, J. R. G. E. Archer Jr., D. D. Bigner, M. R. Zalutsky, Appl. Radiat. Isot. 1989, 40, 485-490.
20. S. Scott-Robson, J. Capala, J. Carlsson, P. Malmborg, H. Lundqvist, Nucl. Med. Biol. 1991, 18, 241-246.
21. M. R. Zalutsky, A. S. Narula, Appl. Radiat. Isot. 1987, 38, 1051-1055.
22. L. A. Khawli, A. I. Kassis, Nucl. Med. Biol. 1989, 16, 727-733.