메뉴 건너뛰기




Volumn 43, Issue 12, 2004, Pages 1555-1558

Self-assembled aggregates of IgGs as templates for the growth of clusters of gold nanoparticles

Author keywords

Antibodies; Antigens; Gold; Nanostructures; Self assembly

Indexed keywords

ANTIGENS; CARBOHYDRATES; CRYSTAL GROWTH; ELECTROLESS PLATING; GOLD; NUCLEATION; SELF ASSEMBLY;

EID: 4544227313     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200353161     Document Type: Article
Times cited : (44)

References (54)
  • 11
    • 0036462502 scopus 로고    scopus 로고
    • a) Q. Wang, T. Lin, L. Tang, J. E. Johnson, M. G. Finn, Angew. Chem. 2002, 114, 477; Angew. Chem. Int. Ed. 2002, 41, 459;
    • (2002) Angew. Chem. Int. Ed. , vol.41 , pp. 459
  • 19
    • 0344878887 scopus 로고    scopus 로고
    • h) C. M. Niemeyer, W. Burger, J. Peplies, Angew. Chem. 1998, 110, 2391; Angew. Chem. Int. Ed. 1998, 37, 2265;
    • (1998) Angew. Chem. Int. Ed. , vol.37 , pp. 2265
  • 22
    • 0029781455 scopus 로고    scopus 로고
    • personal communication
    • A. P. Alivisatos, K. P. Johnsson, X. Peng, T. E. Wilson, C. J. Loweth, M. P. Bruchez, P. G. Schultz, Nature 1996, 382, 609; Professor Matthew B. Francis, personal communication.
    • Francis, M.B.1
  • 30
    • 4544369327 scopus 로고    scopus 로고
    • note
    • Green,[11] Valentine,[12] and others[13] described the spontaneous formation of linear and cyclic nanoscale complexes between polyclonal IgGs[14] (or IgEs) and divalent antigens.
  • 33
  • 36
    • 0032476812 scopus 로고    scopus 로고
    • a) M. Mammen, S.-K. Choi, G. M. Whitesides, Angew. Chem. 1998, 110, 2909; Angew. Chem. Int. Ed. 1998, 37, 2755;
    • (1998) Angew. Chem. Int. Ed. , vol.37 , pp. 2755
  • 42
    • 4544315593 scopus 로고    scopus 로고
    • note
    • c fragment is about 11 nm long [10a,17]
  • 46
    • 4544318020 scopus 로고    scopus 로고
    • note
    • We will report the details of these studies in solution elsewhere. The supporting information includes a representative size-exclusion HPLC chromatogram illustrating the conversion of IgGs to aggregated species.
  • 47
    • 4544381160 scopus 로고    scopus 로고
    • note
    • We separated these aggregates from the non-aggregated protein by FPLC (data not shown). Images of gold nanoparticles grown from a mixture of these purified aggregates appeared indistinguishable from images of particles grown from aggregates of IgGs that were not purified by FPLC.
  • 52
    • 4544294676 scopus 로고    scopus 로고
    • note
    • 4 substrates indicate that washing the surfaces in aqueous solutions does not completely remove protein from the substrates.
  • 53
    • 4544296667 scopus 로고    scopus 로고
    • note
    • We believe the difference in the fraction of aggregated IgGs in solution (≈73% of the protein) and the fraction of clusters of nanoparticles grown from the carbohydrates on the IgGs (15 ± 5%) reflects the less than quantitative yield of the chemical reactions that generate the metal nanoparticles-that is, the oxidation of the carbohydrate units, the reduction of silver ions, and the electroless growth of gold.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.