Regulatory Role of Vitamin D Receptor Gene Variants of BsmI, ApaI, TaqI, and FokI Polymorphisms on Macrophage Phagocytosis and Lymphoproliferative Response to Mycobacterium tuberculosis Antigen in Pulmonary Tuberculosis

Journal of Clinical Immunology

Volumn 24, Issue 5, 2004, Pages 523-532

  Selvaraj, P ^a   Chandra, G ^a   Jawahar, M S ^a   Rani, M Vidya ^a   Rajeshwari, D Nisha ^a   Narayanan, P R ^a  

^a NATIONAL INSTITUTE FOR RESEARCH IN TUBERCULOSIS   (India)

Author keywords

lymphoproliferation; M. tuberculosis antigens; macrophage phagocytosis; pulmonary TB; VDR gene polymorphism; Vit D 3

Indexed keywords

VITAMIN D RECEPTOR;

ADULT; ARTICLE; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA POLYMORPHISM; DOWN REGULATION; FEMALE; GENE FUNCTION; GENOTYPE; HUMAN; HUMAN CELL CULTURE; IMMUNE RESPONSE; LUNG TUBERCULOSIS; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MALE; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; ANTIGENS, BACTERIAL; FEMALE; HUMANS; MACROPHAGES; MALE; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; POLYMORPHISM, GENETIC; RECEPTORS, CALCITRIOL; TUBERCULOSIS;

EID: 4544219889     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JOCI.0000040923.07879.31     Document Type: Article

References (38)

1. Murray CJ, Styblo K, Rouillon A: Tuberculosis in developing countries: Burden, intervention and cost. Bull Int Union Tuberc Lung Dis 65:6-24, 1990
2. Hill AV: The genomics and genetics of human infectious disease susceptibility. Annu Rev Genomics Hum Genet 2:373-400, 2001
3. Bellamy R: Susceptibility to mycobacterial infections: The importance of host genetics. Genes Immun 4:4-11, 2003
4. Dowling GB, Prosser-Thomas EW: Treatment of lupus vulgaris with calciferol. Lancet 1:919-922, 1946
5. Davies PD, Brown RC, Church HA, Woodhead JS: The effect of anti-tuberculosis chemotherapy on vitamin D and calcium metabolism. Tubercle 68:261-266, 1987
6. 3: A novel immunoregulatory hormone. Science 224:1438-1440, 1984
7. 3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells. J Clin Invest 74:657-661, 1984
8. 3, gamma interferon, and control of proliferation of Mycobacterium tuberculosis by human monocytes. Immunology 57:159-163, 1986
9. 3 stimulates phagocytosis but suppresses HLA-DR and CD13 antigen expression in human mononuclear phagocytes. Proc Soc Exp Biol Med 211:244-250, 1996
10. Denis M: Killing of Mycobacterium tuberculosis within human monocytes: Activation by cytokines and calcitriol. Clin Exp Immunol 84:200-206, 1991
11. 3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line. Infect Immun 66:5314-5321, 1998
12. 3 on phagocytic potential of macrophages with live Mycobacterium tuberculosis and lymphoproliferative response in pulmonary tuberculosis. J Clin Immunol 24:249-257, 2004
13. 3 receptors in human leukocytes. Science 221:1181-1183, 1983
14. 3 inhibits gamma-interferon synthesis by normal human peripheral blood lymphocytes. Proc Natl Acad Sci USA 84:3385-3389, 1987
15. Malloy PJ, Feldman D: Vitamin D resistance. Am J Med 106:355-370, 1999
16. Morrison NA, Yeoman R, Kelly PJ, Eisman JA: Contribution of trans-acting factor alleles to normal physiological variability: Vitamin D receptor gene polymorphism and circulating osteocalcin. Proc Natl Acad Sci USA 89:6665-6669, 1992
17. Faraco JH, Morrison NA, Baker A, Shine J, Frossard PM: ApaI dimorphism at the human vitamin D receptor gene locus. Nucleic Acids Res 17:2150, 1989
18. Baker AR, McDonnell DP, Hughes M, Crisp TM, Mangelsdorf DJ, Haussier MR, Pike JW, Shine J, O'Malley BW: Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc Natl Acad Sci USA 85:3294-3298, 1988
19. Morrison NA, Qi JC, Tokita A, Kelly PJ, Crofts L, Nguyen TV, Sambrook PN, Eisman JA: Prediction of bone density from vitamin D receptor alleles. Nature 367:284-287, 1994
20. Arai H, Miyamoto K, Taketani Y, Yamamoto H, Iemori Y, Morita K, Tonai T, Nishisho T, Mori S, Takeda E: A vitamin D receptor gene polymorphism in the translation initiation codon: Effect on protein activity and relation to bone mineral density in Japanese women. J Bone Miner Res 12:915-921, 1997
21. Eccleshall TR, Garnero P, Gross C, Delmas PD, Feldman D: Lack of correlation between start codon polymorphism of the vitamin D receptor gene and bone mineral density in premenopausal French women: The OFELY study. J Bone Miner Res 13:31-35, 1998
22. Bellamy R, Ruwende C, Corrah T, McAdam KP, Thursz M, Whittle HC, Hill AV: Tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene. J Infect Dis 179:721-724, 1999
23. Wilkinson RJ, Llewelyn M, Toossi Z, Patel P, Pasvol G, Lalvani A, Wright D, Lauf M, Davidson RN: Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: A case-control study. Lancet 355:618-621, 2000
24. Selvaraj P, Narayanan PR, Reetha AM: Association of vitamin D receptor genotypes with the susceptibility to pulmonary tuberculosis in female patients & resistance in female contacts. Indian J Med Res 111:172-179, 2000
25. Selvaraj P, Chandra G, Kurian SM, Reetha AM, Narayanan PR: Association of vitamin D receptor gene variants of BsmI, ApaI and FokI polymorphisms with susceptibility or resistance to pulmonary tuberculosis. Curr Sci 84:1564-1568, 2003
26. Nagai S, Wiker HG, Harboe M, Kinomoto M: Isolation and partial characterization of major protein antigens in the culture fluid of Mycobacterium tuberculosis. Infect Immun 59:372-382, 1991
27. Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215, 1988
28. Sainz J, Van Tornout JM, Loro ML, Sayre J, Roe TF, Gilsanz V: Vitamin D-receptor gene polymorphisms and bone density in prepubertal American girls of Mexican descent. N Engl J Med 337:77-82, 1997
29. Correa P, Rastad J, Schwarz P, Westin G, Kindmark A, Lundgren E, Akerstrom G, Carling T: The vitamin D receptor (VDR) start codon polymorphism in primary hyperparathyroidism and parathyroid VDR messenger ribonucleic acid levels. J Clin Endocrinol Metab 84:1690-1694, 1999
30. 3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages. Blood 82:1300-1307, 1993
31. 3. Curr Opin Nephrol Hypertens 4:313-318, 1995
32. 3 by cells recovered by bronchoalveolar lavage and the role of this metabolite in calcium homeostasis. Am Rev Respir Dis 138:984-989, 1988
33. 3 production by T lymphocytes and alveolar macrophages recovered by lavage from normocalcemic patients with tuberculosis. J Clin Invest 85:1588-1593, 1990
34. Sharma OP: Hypercalcemia in granulomatous disorders: A clinical review. Curr Opin Pul Med 6:442-447, 2000
35. Beelman CA, Parker R: Degradation of mRNA in eukaryotes. Cell 81:179-183, 1995
36. Juratka PW, Remus LS, Whitfield GK, Thompson PD, Hsieh JC, Zitzer H, Tavakkoli P, Galligan MA, Dang HT, Haussler CA, Haussler MR: The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB. Mol Endocrinol 14:401-420, 2000
37. Whitfield GK, Remus LS, Jurutka PW, Zitzer H, Oza AK, Dang HT, Haussler CA, Galligan MA, Thatcher ML, Encinas Dominguez C, Haussler MR: Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene. Mol Cell Endocrinol 177:145-159, 2001
38. 3. Clin Endocrinol (Oxf) 52:211-216, 2000