Association of single nucleotide polymorphisms of Nrf2 promoter region with susceptibility to vitiligo

National Medical Journal of China

Volumn 88, Issue 14, 2008, Pages 969-972

  Zhou, Miao Ni ^a   Xu, Ai E ^a   Lu, Liang Jun ^a   Li, Yong Wei ^a   Zhao, De Kuang ^a   Guan, Cui Ping ^a  

^a THE THIRD PEOPLE S HOSPITAL OF HANGZHOU   (China)

Author keywords

Nrf2; Polymorphism, single nucleotide; Vitiligo

Indexed keywords

TRANSCRIPTION FACTOR NRF2;

ADULT; ARTICLE; BLOOD SAMPLING; CHI SQUARE TEST; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEVICE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENOTYPE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PROMOTER REGION; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE; VARIABLE NUMBER OF TANDEM REPEAT; VITILIGO;

ADULT; ALLELES; BASE SEQUENCE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; NF-E2-RELATED FACTOR 2; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RISK FACTORS; VITILIGO;

EID: 45349107837     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Kobayashi A, Ohta T, Yamamoto M. Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes. Methods Enzymol, 2004, 378: 273-286.
2. Yamamoto T, Yoh K, Kobayashi A, et al. Identification of polymorphisms in the promoter region of the human NRF2 gene. Biochem Biophys Res Commun, 2004, 321: 72-79.
3. Maresca V, Roccella M, Roccella F, et al. Increased sensitivity to peroxidative agents as a possible pathogenic factor of melanocyte damage in vitiligo. J Int Dermatol, 1997, 109: 310-313.
4. Casp CB, She JX, McCormack WT. Genetic association of the catalase gene (CAT) with vitiligo susceptibility. Pigment Cell Res, 2002, 15: 62-66.
5. Kobayashi M, Yamamoto M. Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal, 2005, 7: 385-394.
6. Cho HY, Jedlicka AE, Reddy SP, et al. Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene. Am J Respir Cell Mol Biol, 2002, 26: 42-51.