Murine monoclonal antibodies neutralizing the cytotoxic activity of diphtheria toxin

Asian Pacific Journal of Allergy and Immunology

Volumn 26, Issue 1, 2008, Pages 47-55

  Usuwanthim, Kanchana ^a   Pootong, Anek ^a   Chaisri, Urai ^b   Tongtawe, Pongsri ^a   Tapchaisri, Pramuan ^a   Chongsa Nguan, Manas ^b   Chaicumpa, Wanpen ^c  

^a THAMMASAT UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

DIPHTHERIA ANTIBODY; DIPHTHERIA PERTUSSIS TETANUS VACCINE; DIPHTHERIA TOXIN; DIPHTHERIA VACCINE; EPITOPE; MONOCLONAL ANTIBODY;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHANNEL GATING; CONTROLLED STUDY; CORYNEBACTERIUM DIPHTHERIAE; CYTOSOL; CYTOTOXICITY; DIPHTHERIA; ENZYME ACTIVE SITE; ENZYME LINKED IMMUNOSORBENT ASSAY; HYBRIDOMA; HYPOTHESIS; MEMBRANE CHANNEL; MOLECULAR CLONING; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; RECEPTOR BINDING; SPLEEN; VERO CELL; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, MONOCLONAL; CERCOPITHECUS AETHIOPS; DIPHTHERIA TOXIN; HYBRIDOMAS; MICE; MICE, INBRED BALB C; NEUTRALIZATION TESTS; PEPTIDE FRAGMENTS; VERO CELLS;

EID: 45349099668     PISSN: 0125877X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Pappenheimer Jr AM, Murphy JR. Studies on the epidemiology of diphtheria. Lancet 1983; 2: 923-6.
2. Collier RJ. Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century. Toxicon 2001; 39: 1793-803.
3. Freeman VJ. Studies on the virulence of bacteriophage infected strains of C. diphtheriae. J Bacteriol 1951; 61: 675-88.
4. Uchida Jr T, Gill DM, Pappenheimer Jr AM. Mutation in the structural gene for diphtheria toxin carried by temperate phage. Nature New Biol 1971; 233: 8-11.
5. Matsuda M, Barksdale L. Phage directed-synthesis of diphtheria toxin in non-toxigenic Corynebacterium diphtheriae. Nature 1966; 210: 911-3.
6. Gill DM, Pappenheimer Jr AM. Structure-activity relationships in diphtheria toxin. J Biol Chem 1971; 246: 1485-91.
7. Collier RJ. Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors. J Mol Biol 1967; 25: 83-98.
8. Honjo T, Nishizuka Y, Hayaishi O, Kato I. Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. J Biol Chem 1968; 243: 3553-5.
9. Gill DM, Pappenheimer Jr AM, Brown R, Kurnick JT. Studies on the mode of action of diphtheria toxin. VII. Toxin stimulated hydrolysis of nicotinamide adenine dinucleotide in mammalian cell extracts. J Exp Med 1969; 129: 1-21.
10. Umata T, Moriyama YM, Mekada E. The cytotoxicity of diphtheria toxin and its degradation in intact Vero cells are inhibited by bafilomycin A1, a specific inhibitor of vascuolar type H+-ATPase. Biol Chem 1990; 265: 21940-5.
11. Keen JH, Maxfield FR, Hardegree MC, Habig WH. Receptor mediated endocytosis of diphtheria toxin by cells in culture. Proc Natl Acad Sci USA 1982; 79: 2912-6.
12. Donovan JJ, Simon MI, Draper PK, Montal M. Diphtheria toxin forms transmembrane channel in planar lipid bilayers. Proc Natl Acad Sci 1981; 78: 172-6.
13. Kagan BL, Finkelstein A, Colombini M. Diphtheria toxin fragment forms large pores in phospholipids bilayer membranes. Proc Natl Acad Sci USA 1981: 78: 4950-4.
14. MacGowan AP. Coryneform bacteria, listeria and erysipelothrix. In: Greenwood D, Slack RCB, Pentherer JF. Eds. Medical Microbiology. A Guide to Microbial Infection: Pathogenesis, Immunity, Laboratory Diagnosis and Control. 15th Edition. Churchill Livingstone, New York 1997; pp. 191-9.
15. Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975; 256: 495-7.
16. Saengjaruk P, Chaicumpa W, Watt G, et al. Diagnosis of human leptospirosis by monoclonal antibody based-antigen detection in urine. J Clin Microbiol 2002; 40: 480-9.
17. Pootong A, Budhirakkul P, Tongtawe P, Tapchaisri P, Chongsa-nguan M, Chaicumpa W. Monoclonal antibody that neutralizes pertussis toxin activities. Asian Pac J Allergy Immunol 2007; 25: 37-45.
18. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-5.
19. Gentry MK, Dalrymple JM. Quantitative microtiter cytotoxicity assay for Shigella toxin. J Clin Microbiol 1980; 12: 361-6.
20. Miyamura K, Nishio S, Ito A, Murata R, Kono R. Micro cell culture method for determination of diphtheria toxin and antitoxin titres using Vero cells. II. Comparison with rabbit skin method and practical application for seroepidemiological studies. J Biol Stand 1974; 2: 203-9.
21. Casadevall A, Scharff MD. Return to the past: the case for antibody-based therapies in infectious diseases. Clin Infect Dis 1995; 21: 150-61.
22. Dolby JM, Dolby DE, Brinne-Shanbury CJ. The effects of humoral, cellular and non-specific immunity on intracerebral Bordetella pertussis infection in mice. J Hyg 1975; 74: 85-102.
23. Buchwald UK, Pirofski L. Immune therapy for infectious diseases at the dawn of the 21st century: the past, present and future role of antibody therapy, therapeutic vaccination and biological response modifiers. Curr Pharm Des 2003; 9: 945-68.
24. Naglich JG, Matherall JE, Russel DWQ, Eidels L. Expression cloning of a diphtheria toxin receptor: identity with a hairpin-binding EGF-like growth factor precursor. Cell 1992; 69: 1051-61.
25. Mitamura T, Iwamoto R, Umata T, Yomo T, Urabe I, Tsuneoka M, Mekada EJ. The 27-kD diphtheria toxin -receptor associated protein (DRAP27) from Vero cell is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin sensitive cells. Cell Biol 1992; 118: 1389-99.
26. Roft JM, Eidels L. Structure-function analysis of diphtheria toxin by use of monoclonal antibodies. Infect Immun 1993; 61: 984-1003.
27. Zalman LS, Wisnieski BJ. Mechanism of insertion of diphtheria toxin: peptide entry and pore size determinations. Proc Natl Acad Sci USA 1984; 81: 3341-5.