Targeting mTOR in HIV-negative classic Kaposi's sarcoma

Sarcoma

Volumn 2008, Issue , 2008, Pages

  Merimsky, Ofer ^a,b   Jiveliouk, Irina ^a,b   Sagi Eisenberg, Ronit ^b  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; DOXORUBICIN; ETOPOSIDE; FLUORODEOXYGLUCOSE; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; VINBLASTINE;

AGED; ANEMIA; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DRUG DOSE INCREASE; DRUG TARGETING; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KAPOSI SARCOMA; METASTASIS; MULTIPLE CYCLE TREATMENT; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; STOMATITIS; WEAKNESS;

EID: 45349095871     PISSN: 1357714X     EISSN: 13691643     Source Type: Journal    
DOI: 10.1155/2008/825093     Document Type: Article

References (25)

1. Brash D. B., Bale A. E., DeVita V. T. Jr., Hellman S., Rosenberg S., Molecular biology of skin cancer Cancer Principles and Practice of Oncology 2000 chapter 41 Philadelphia, Pa, USA Lippincott Williams & Wilkins 1971 1975
2. McCaffrey P., Sirolimus does double duty after organ transplantation The Lancet Oncology 2005 6 5 261
3. Mohsin N., Budruddin M., Pakkyara A., Complete regression of visceral Kaposi's sarcoma after conversion to sirolimus Experimental and Clinical Transplantation 2005 3 2 366 369
4. Vasanawala M. S., Wang Y., Quon A., Gambhir S. S.
5. Dupont P., Warrens A. N.
6. Keith C. T., Schreiber S. L., PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints Science 1995 270 5233 50 51
7. Jefferies H. B. J., Fumagalli S., Dennis P. B., Reinhard C., Pearson R. B., Thomas G., Rapamycin suppresses 5′ TOP mRNA translation through inhibition of p 70s6k The EMBO Journal 1997 16 12 3693 3704
8. Sonenberg N.
9. Fingar D. C., Richardson C. J., Tee A. R., Cheatham L., Tsou C., Blenis J.
10. Huang S., Bjornsti M. A., Houghton P. J., Rapamycins: mechanism of action and cellular resistance Cancer Biology & Therapy 2003 2 3 222 232
11. Chen J.
12. Chen J., Zheng X.-F., Brown E. J., Schreiber S. L., Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin- associated protein and characterization of a critical serine residue Proceedings of the National Academy of Sciences of the United States of America 1995 92 11 4947 4951
13. Mita M. M.
14. Guba M., von Breitenbuch P., Steinbauer M., Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor Nature Medicine 2002 8 2 128 135
15. Dancey J. E.
16. Shi Y., Frankel A., Radvanyi L. G., Penn L. Z., Miller R. G., Mills G. B., Rapamycin enhances apoptosis and increases sensitivity to cisplatin in vitro Cancer Research 1995 55 9 1982 1988
17. Eshleman J. S., Carlson B. L., Mladek A. C., Kastner B. D., Shide K. L., Sarkaria J. N., Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy Cancer Research 2002 62 24 7291 7297
18. Huang S., Houghton P. J., Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic Current Opinion in Investigational Drugs 2002 3 2 295 304
19. Montaner S.
20. Chang Y., Cesarman E., Pessin M. S., Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma Science 1994 266 5192 1865 1869
21. Montaner S., Sodhi A., Molinolo A., Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes Cancer Cell 2003 3 1 23 36
22. Dourmishev L. A., Dourmishev A. L., Palmeri D., Schwartz R. A., Lukac D. M.
23. Sodhi A., Montaner S., Patel V., Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor Proceedings of the National Academy of Sciences of the United States of America 2004 101 14 4821 4826
24. Manning B. D., Cantley L. C.
25. Richardson C. J., Schalm S. S., Blenis J.