Chemical carcinogenesis studies in nonhuman primates

Proceedings of the Japan Academy Series B: Physical and Biological Sciences

Volumn 84, Issue 6, 2008, Pages 176-188

  Takayama, Shozo ^a,c   Thorgeirsson, Unnur P ^b   Adamson, Richard H ^b  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CANCER INSTITUTE   (United States)

^c MEIJI SEIKA KAISHA LTD   (Japan)

Author keywords

Chemical carcinogenesis; Lifetime administration; Nonhuman primate

Indexed keywords

CARCINOGEN;

ANIMAL; CERCOPITHECUS; CHEMICALLY INDUCED DISORDER; EXPERIMENTAL NEOPLASM; MACACA; REVIEW;

ANIMALS; CARCINOGENS; CERCOPITHECUS AETHIOPS; MACACA FASCICULARIS; MACACA MULATTA; NEOPLASMS, EXPERIMENTAL;

CERCOPITHECIDAE; CERCOPITHECUS AETHIOPS; MACACA MULATTA; PRIMATES; RODENTIA;

EID: 45349093856     PISSN: 03862208     EISSN: 13492896     Source Type: Journal    
DOI: 10.2183/pjab.84.176     Document Type: Review

References (42)

1. Iatropoulos, M.J. (1992) Accelerated rodent bioassay predictive of chemical carcinogenesis. Exp. Toxicol. Pathol. 44, 481-487.
2. Gold, L.S., Slone, T.H., Manley, N.B. and Bernstein, L. (1991) Target organs in chronic bioassays of 533 chemical carcinogens. Environ Health Perspect. 93, 233-246.
3. Vainio, H. and Wilbourn, J. (1993) Cancer etiology: agents causally associated with human cancer. Pharmacol. Toxicol. 72 Suppl. 1, 4-11.
4. Dalgard, D.W. (1994-1997) Introduction, Biological Markers, and Therapy of Tumors in Primates. Final Report of Contract No. NO1-CP-40510, The National Cancer Institute, Bethesda, MD, USA, Laboratory Project Identification: CHV Study No. 421-166, 1-177.
5. Thorgeirsson, U.P., Dalgard, D.W., Reeves, J. and Adamson, R.H. (1994) Tumor incidence in a chemical carcinogenesis study of nonhuman primates. Regul. Toxicol. Pharmacol. 19, 130-151.
6. IARC (2004) Some drinking-water disinfectants and contaminants, including arsenic. IARC Monogr. Eval. Carcinog. Risks Hum. 84, 41-267.
7. Takayama, S., Makita, T. and Thorgeirsson, U.P. (1999) Color Atlas of Nonhuman Primate Histology. Japan Scientific Society Press, Tokyo, S. Karger AG, Basel.
8. Takayama, S., Fukushima, S. and Thorgeirsson, U.P. (2000) Atlas of Spontaneous Tumors in Nonhuman Primates. Japan Scientific Society Press, Tokyo, S. Karger AG, Basel.
9. Lindower, P.D. and Skorton, D.J. (1992) High-dose Cancer Therapy. Williams and Wilkins, Baltimore, pp. 507-517.
10. Devita, V.T. Jr., Serpick, A.A. and Carbone, P.P. (1970) Combination chemotherapy in the treatment of advanced Hodgkin's disease. Ann. Intern. Med. 73, 881-895.
11. IARC (1981) Some antineoplastic and immunosuppressive agents. IARC Monogr. Eval. Carcinog. Risks Hum. 26, 165-202.
12. Sieber, S.M., Correa, P., Dalgard, D.W. and Adamson, R.H. (1978) Carcinogenic and other adverse effects of procarbazine in nonhuman primates. Cancer Res. 38, 2125-2134.
13. Adamson, R.H., Krollkowski, F.J., Correa, P., Sieber, S.M. and Dalgard, D.W. (1977) Carcinogenecity of 1-methyl-1-nitrosourea in nonhuman primates. J. Natl. Cancer Inst. 59, 415-422.
14. IARC (1999) Some chemicals that cause tumors of the kidney or urinary bladder in rodents and some other substances. IARC Monogr. Eval. Carcinog. Risks Hum. 73, 517-624.
15. IARC (1999) Working Group Consensus Report. IARC Scientific Publication 147, 1-32.
16. Takayama, S., Sieber, S.M., Adamson, R.H., Thorgeirsson, U.P., Dalgard, D.W., Arnold, L.L., Cano, M., Eklund, S. and Cohen, S.M. (1998) Long-term feeding of sodium saccharin to nonhuman primates: implications for urinary tract cancer. J. Natl. Cancer Inst. 90, 19-25.
17. Price, J.M., Biava, C.G., Oser, B.L., Vogin, E.E., Steinfeld, J. and Ley, H.L. (1970) Bladder tumors in rats fed cyclohexylamine or high doses of a mixture of cyclamate and saccharin. Science 167, 1131-1132.
18. Renwick, A.G. (1986) The metabolism of intense sweeteners. Xenobiotica 16, 1057-1071.
19. Bopp, B.A., Sonders, R.C. and Kesterson, J.W. (1986) Toxicological aspects of cyclamate and cyclohexylamine. Crit. Rev. Toxicol. 16, 213-306.
20. Takayama, S., Renwick, A.G., Johansson, S.L., Thorgeirsson, U.P., Tsutsumi, M., Dalgard, D.W. and Sieber, S.M. (2000) Long-term toxicity and carcinogenicity study of cyclamate in nonhuman primates. Toxicol. Sci. 53, 33-39.
21. Sugimura, T. (1995) Heterocyclic Amines in Cooked Foods: Possible Human Carcinogens. Princeton Scientific Pub. Co. Inc., Princeton, NJ, pp. 214-231.
22. Sugimura, T. (1986) Studies on environmental chemical carcinogenesis in Japan. Science 233, 312-318.
23. Adamson, R.H., Thorgeirsson, U.P., Snyderwine, E.G., Thorgeirsson, S.S., Reeves, J., Dalgard, D.W., Takayama, S. and Sugimura, T. (1990) Carcinogenicity of 2-amino-3-methylimidazo-[4,5-f]quinoline in nonhuman primates: induction of tumors in three macaques. Jpn. J. Cancer Res. 81, 10-14.
24. Ogawa, K., Tsuda, H., Shirai, T., Ogiso, T., Wakabayashi, K., Dalgard, D.W., Thorgeirsson, U.P., Thorgeirsson, S.S., Adamson, R.H. and Sugimura, T. (1999) Lack of carcinogenicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in cynomolgus monkeys. Jpn. J. Cancer Res. 90, 622-628.
25. Adamson, R.H., Correa, P., Sieber, S.M., Mcintire, K.R. and Dalgard, D.W. (1976) Carcinogenicity of aflatoxin B1 in rhesus monkeys: two additional cases of primary liver cancer. J. Natl. Cancer Inst. 57, 67-78.
26. Tomatis, L., Turusov, V., Day, N. and Charles, R.T. (1972) The effect of long-term exposure to DDT on CF-1 mice. Int. J. Cancer 10, 489-506.
27. IARC (1991) Occupational exposures in insecticide application and some pesticides. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, IARC Monogr. Eval. Carcinog. Risks Hum. 53, 179-249.
28. Takayama, S., Sieber, S.M., Dalgard, D.W., Thorgeirsson, U.P. and Adamson, R.H. (1999) Effects of long-term oral administration of DDT on nonhuman primates. J. Cancer Res. Clin. Oncol. 125, 219-225.
29. Lapis, K., Zalatnai, A., Timar, F. and Thorgeirsson, U.P. (1995) Quantitative evaluation of lysozyme- and CD68-positive Kupffer cells in diethylnitrosamine-induced hepatocellular carcinomas in monkeys. Carcinogenesis 16, 3083-3085.
30. Weisburger, E.K. (1977) Bioassay program for carcinogenic hazards of cancer chemotherapeutic agents. Cancer 40, 1935-1949.
31. Adamson, R.H. and Sieber, S.M. (1983) Origins of Human Cancer. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 429-443.
32. Kolaric, K. (1977) Combination chemotherapy with 1-methyl-1-nitrosourea (MNU) and cyclophosphamide in solid tumors. Z. Krebsforsh. Klin. Onkol. 89, 311-319.
33. Karchmer, R.K., Amare, M., Larsen, W.E., Mallouk, A.G. and Caldwell, G.G. (1974) Alkylating agents as leukemogens in multiple myeloma. Cancer 33, 1103-1107.
34. Kyle, R.A., Pierre, R.V. and Bayrd, E.D. (1974) Primary amyloidosis and acute leukemia associated with melphalan therapy. Blood 44, 333-337.
35. Schmahl, D., Habs, M., Lorenz, M. and Wagner, I. (1982) Occurrence of second tumors in man after anticancer drug treatment. Cancer Treat. Rev. 9, 167-194.
36. Smith, R.L. and Williams, R.T. (1974) Comparative metabolism of drugs in man and monkeys. J. Med. Primatol. 3, 138-152.
37. Snyderwine, E.G., Schut, H.A., Adamson, R.H., Thorgeirsson, U.P. and Thorgeirsson, S.S. (1992) Metabolic activation and genotoxicity of heterocyclic arylamines. Cancer Res. 52, 2099s-2102s.
38. Snyderwine, E.G., Turesky, R.J., Buonarati, M.H., Turlehaub, K.W. and Adamson, R.H. (1995) Heterocyclic Amines in Cooked Foods: Possible Human Carcinogens. Princeton Scientific Pub. Co. Inc., Princeton, NJ, pp. 60-69.
39. Snyderwine, E.G., Turesky, R.J., Turteltaub, K.W., Davis, C.D., Sadrieh, N., Schut, H.A., Nagao, M., Sugimura, T., Thorgeirsson, U.P., Adamson, R.H. and Thorgeirsson, S.S. (1997) Metabolism of food-derived heterocyclic amines in nonhuman primates. Mutat. Res. 376, 203-210.
40. Sadrieh, N. and Snyderwine, E.G. (1995) Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]-quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). Carcinogenesis 16, 1549-1555.
41. Davis, C.D., Schut, H.A. and Snyderwine, E.G. (1993) Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats. Carcinogenesis 14, 2091-2096.
42. Edwards, R.J., Murray, B.P., Murray, S., Schulz, T., Neubert, D., Gant, T.W., Thorgeirsson, S.S., Boobis, A.R. and Davies, D.S. (1994) Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human. Carcinogenesis 15, 829-836.