Chromosome 11 genomic changes in parathyroid adenoma and hyperplasia: Array CGH, FISH, and tissue microarrays

Genes Chromosomes and Cancer

Volumn 47, Issue 8, 2008, Pages 639-648

  Yi, Y ^a   Nowak, Norma J ^b   Pacchia, Annmarie L ^c   Morrison, Carl ^c  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BENIGN TUMOR; CCND1 GENE; CHROMOSOME 11; CHROMOSOME 11Q; CHROMOSOME DELETION; CHROMOSOME LOSS; COMPARATIVE GENOMIC HYBRIDIZATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE EXPRESSION PROFILING; GENE LOCUS; GENE MAPPING; GENE TRANSLOCATION; GENOMICS; HUMAN; HUMAN TISSUE; HYPERPARATHYROIDISM; MEN1 GENE; PARATHYROID ADENOMA; PARATHYROID HYPERPLASIA; PRIORITY JOURNAL; TISSUE MICROARRAY; UREMIA;

CHROMOSOME ABERRATIONS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 11; CYCLINS; GENE EXPRESSION PROFILING; GENOME, HUMAN; GENOMICS; HUMANS; HYPERPLASIA; IN SITU HYBRIDIZATION, FLUORESCENCE; NUCLEIC ACID HYBRIDIZATION; PARATHYROID NEOPLASMS; PROTO-ONCOGENE PROTEINS; TISSUE ARRAY ANALYSIS;

EID: 45349090959     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20565     Document Type: Article

References (32)

1. Arnold A, Kim HG, Gaz RD, Eddy RL, Fukushima Y, Byers MG, Shows TB, Kronenberg HM. 1989. Molecular cloning and chromosomal mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma. J Clin Invest 83:2034-2040.
2. Agarwal SK, Schrock E, Kester MB, Burns AL, Heffess CS, Ried T, Marx SJ. 1998. Comparative genomic hybridization analysis of human parathyroid tumors. Cancer Genet Cytogenet 106:30-36.
3. Carling T, Correa P, Hessman O, Hedberg J, Skogseid B, Lindberg D, Rastad J, Westin G, Akerstrom G. 1998. Parathyroid MEN1 gene mutations in relation to clinical characteristics of nonfamilial primary hyperparathyroidism. J Clin Endocrinol Metab 83:2960-2963.
4. Carling T, Du Y, Fang W, Correa P, Huang S. 2003. Intragenic allelic loss and promoter hypermethylation of the RIZ1 tumor suppressor gene in parathyroid tumors and pheochromocytomas. Surgery 134:932-939.
5. Cetani F, Pardi E, Vignali E, Borsari S, Picone A, Cianferotti L, Ambrogini E, Miccoli P, Pinchera A, Marcocci C. 2002. MEN1 gene alterations do not correlate with the phenotype of sporadic primary hyperparathyroidism. J Endocrinol Invest 25:508-512.
6. Correa P, Juhlin C, Rastad J, Akerstrom G, Westin G, Carling T. 2002. Allelic loss in clinically and screening-detected primary hyperparathyroidism. Clin Endocrinol (Oxf) 56:113-117.
7. Falchetti A, Bale AE, Amorosi A, Bordi C, Cicchi P, Bandini S, Marx SJ, Brandi ML. 1993. Progression of uremic hyperparathyroidism involves allelic loss on chromosome 11. J Clin Endocrinol Metab 76:139-144.
8. Farnebo F, Teh BT, Kytola S, Svensson A, Phelan C, Sandelin K, Thompson NW, Hoog A, Weber G, Farnebo LO, Larsson C. 1998. Alterations of the MEN1 gene in sporadic parathyroid tumors. J Clin Endocrinol Metab 83:2627-2630.
9. Farnebo F, Farnebo LO, Nordenstrom J, Larsson C. 1997. Allelic loss on chromosome 11 is uncommon in parathyroid glands of patients with hypercalcaemic secondary hyperparathyroidism. Eur J Surg 163:331-337.
10. Farnebo F, Kytola S, Teh BT, Dwight T, Wong FK, Hoog A, Elvius M, Wassif WS, Thompson NW, Farnebo LO, Sandelin K, Larsson C. 1999. Alternative genetic pathways in parathyroid tumorigenesis. J Clin Endocrinol Metab 84:3775-3780.
11. Forsberg L, Bjorck E, Hashemi J, Zedenius J, Hoog A, Farnebo LO, Reimers M, Larsson C. 2005. Distinction in gene expression profiles demonstrated in parathyroid adenomas by high-density oligoarray technology. Eur J Endocrinol 152:459-470.
12. Forsberg L, Villablanca A, Valimaki S, Farnebo F, Farnebo LO, Lagercrantz S, Larsson C. 2001. Homozygous inactivation of the MEN1 gene as a specific somatic event in a case of secondary hyperparathyroidism. Eur J Endocrinol 145:415-420.
13. Garcia JL, Tardio JC, Gutierrez NC, Gonzalez MB, Polo JR, Hernandez JM, Menarguez J. 2002. Chromosomal imbalances identified by comparative genomic hybridization in sporadic parathyroid adenomas. Eur J Endocrinol 146:209-213.
14. Haven CJ, Howell VM, Eilers PH, Dunne R, Takahashi M, van Puijenbroek M, Furge K, Kievit J, Tan MH, Fleuren GJ, Robinson BG, Delbridge LW, Philips J, Nelson AE, Krause U, Dralle H, Hoang-Vu C, Gimm O, Morreau H, Marsh DJ, Teh BT. 2004. Gene expression of parathyroid tumors: Molecular subclassification and identification of the potential malignant phenotype. Cancer Res 64:7405-7411.
15. Hemmer S, Wasenius VM, Haglund C, Zhu Y, Knuutila S, Franssila K, Joensuu H. 2001. Deletion of 11q23 and cyclin D1 overexpression are frequent aberrations in parathyroid adenomas. Am J Pathol 158:1355-1362.
16. Heppner C, Kester MB, Agarwal SK, Debelenko LV, Emmert-Buck MR, Guru SC, Manickam P, Olufemi SE, Skarulis MC, Doppman JL, Alexander RH, Kim YS, Saggar SK, Lubensky IA, Zhuang Z, Liotta LA, Chandrasekharappa SC, Collins FS, Spiegel AM, Burns AL, Marx SJ. 1997. Somatic mutation of the MEN1 gene in parathyroid tumours. Nat Genet 16:375-378.
17. Karges W, Jostarndt K, Maier S, Flemming A, Weitz M, Wissmann A, Feldmann B, Dralle H, Wagner P, Boehm BO. 2000. Multiple endocrine neoplasia type 1 (MEN1) gene mutations in a subset of patients with sporadic and familial primary hyperparathyroidism target the coding sequence but spare the promoter region. J Endocrinol 166:1-9.
18. Miedlich S, Krohn K, Lamesch P, Muller A, Paschke R. 2000. Frequency of somatic MEN1 gene mutations in monoclonal parathyroid tumours of patients with primary hyperparathyroidism. Eur J Endocrinol 143:47-54.
19. Morrison C, Marsh W, Jr. Frankel WL. 2002. A comparison of CD10 to pCEA, MOC-31, and hepatocyte for the distinction of malignant tumors in the liver. Mod Pathol 15:1279-1287.
20. Morrison C, Farrar W, Kneile J, Williams N, Liu-Stratton Y, Bakaletz A, Aldred M, Eng C. 2004. Molecular classification of parathyroid neoplasia by gene expression profiling. Am J Pathol 165:565-576.
21. Morrison C, Radmacher M, Mohammed N, Suster D, Auer H, Jones S, Riggenbach J, Kelbick N, Bos G, Mayerson J. 2005. MYC Amplification and Polysomy 8 in Chondrosarcoma: Array CGH, FISH, and Association with Outcome. J Clin Oncol 23:9369-9376.
22. Pourani J, Kaserer K, Pfragner R. 2002. Cytogenetic and molecular analyses of multiple endocrine neoplasias of the MEN1 syndrome. Int J Oncol 20:971-976.
23. Rosen JE, Costouros NG, Lorang D, Burns AL, Alexander HR, Skarulis MC, Cochran C, Pingpank JF, Marx SJ, Spiegel AM, Libutti SK. 2005. Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas. Ann Surg Oncol 12:412-416.
24. Rosenberg CL, Kim HG, Shows TB, Kronenberg HM, Arnold A. 1991. Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors. Oncogene 6:449-453.
25. Rowley JD. 1999. The role of chromosome translocations in leukemogenesis. Simen Hematol 36:59-72.
26. Slebos RJ, Yi Y, Ely K, Carter J, Evjen A, Zhang X, Shyr Y, Murphy BM, Cmelak AJ, Burkey BB, Netterville JL, Levy S, Yarbrough WG, Chung CH. 2006. Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma. Clin Cancer Res 12:701-709.
27. Smith LT, Mayerson J, Nowak NJ, Suster D, Nehad Mohammed N, Long S, Auer HA, Jones S, McKeegan C, Young G, Bos G, Plass C, Morrison C. 2006. 20q11.1 Amplification in giant cell tumor of bone: Array CGH, FISH, and association with outcome. Genes Chromosomes Cancer 45:957-966.
28. Tahara H, Imanishi Y, Yamada T, Tsujimoto Y, Tabata T, Inoue T, Inaba M, Morii H, Nishizawa Y. 2000. Rare somatic inactivation of the multiple endocrine neoplasia type 1 gene in secondary hyperparathyroidism of uremia. J Clin Endocrinol Metab 85: 4113-4117.
29. Tanaka C, Uchino S, Noguchi S, Nishioka T, Yamasaki H, Hashimoto K, Yoshimoto K. 2002. Biallelic inactivation by somatic mutations of the MEN1 gene in sporadic parathyroid tumors. Cancer Lett 175:175-179.
30. Uchino S, Noguchi S, Sato M, Yamashita H, Yamashita H, Watanabe S, Murakami T, Toda M, Ohshima A, Futata T, Mizukoshi T, Koike E, Takatsu K, Terao K, Wakiya S, Nagatomo M, Adachi M. 2000. Screening of the Men1 gene and discovery of germ-line and somatic mutations in apparently sporadic parathyroid tumors. Cancer Res 60:5553-5557.
31. Woodard GE, Lin L, Zhang JH, Agarwal SK, Marx SJ, Simonds WF. 2005. Parafibromin, product of the hyperparathyroidism-jaw tumor syndrome gene HRPT2, regulates cyclin D1/PRAD1 expression. Oncogene 24:1272-1276.
32. Yi Y, Mirosevich J, Shyr Y, Matusik R, George AL, Jr. 2005. Coupled analysis of gene expression and chromosomal location. Genomics 85:401-412.