Ciprofloxacin-mediated cell proliferation inhibition and G2/M cell cycle arrest in rat tendon cells

Arthritis and Rheumatism

Volumn 58, Issue 6, 2008, Pages 1657-1663

  Tsai, Wen Chung ^a   Hsu, Chih Chin ^a   Tang, Fuk Tan ^a   Wong, Alice M K ^a   Chen, Yen Ching ^a   Pang, Jong Hwei S ^b  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 1; CIPROFLOXACIN; CYCLIN B; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; CYCLINE; MESSENGER RNA; POLO LIKE KINASE 1;

ACHILLES TENDON; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CHROMOSOME; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; METAPHASE; MITOSIS; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TENDINITIS; TENDON; UPREGULATION; WESTERN BLOTTING;

ACHILLES TENDON; ANIMALS; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; CIPROFLOXACIN; CYCLIN-DEPENDENT KINASES; CYCLINS; NUCLEIC ACID SYNTHESIS INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; TENDINOPATHY;

EID: 45349087689     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.23518     Document Type: Article

References (24)

1. Pierfitte C, Royer RJ. Tendon disorders with fluoroquinolones. Therapie 1996;51:419-20.
2. Zabraniccki L, Negrier I, Vergne P, Arnaud M, Bonnet C, Bertin P, et al. Fluoroquinolone induced tendinopathy: reports of 6 cases. J Rheumatol 1996;23:516-20.
3. Kato M, Takada S, Kashida Y, Nomura M. Histological examination on Achilles tendon lesions induced by quinolone antibacterial agents in juvenile rats. Toxicol Pathol 1995;23:385-92.
4. Shakibaci M, Stahlmann R. Ultrastructure of Achilles tendon from rats after treatment with fleroxacin. Arch Toxicol 2001;75:97-102.
5. Williams RJ, Attia E, Wickiewicz TL, Hannafin JA. The effect of ciprofloxacin on tendon, paratcnon, and capsular fibroblast metabolism. Am J Sports Med 2000;28:364-9.
6. Bernard-Beaubois K, Hecquet C, Hayem G, Rat P, Adolphe M. In vitro study of cytotoxicity of quinolones on rabbit tenocytes. Cell Biol Toxicol 1998;14:283-92.
7. Corps AN, Harrall RL, Curry VA, Fenwick SA, Hazleman BL, Riley GP. Ciprofloxacin enhances the stimulation of matrix metalloproteinase 3 expression by interleukin-1 in human tendon-derived cells: a potential mechanism of fluoroquinolone-induced tendinopathy. Arthritis Rheum 2002;46:3034-40.
8. Sherr CJ. Cancer cell cycles. Science 1996;274:1672-7.
9. Pines J. Protein kinases and cell cycle control. Semin Cell Biol 1994;5:399-408.
10. Aranha O, Wood DP Jr, Sarkar FH. Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line. Clin Cancer Res 2000;6:891-900.
11. Tsai WC, Pang JH, Hsu CC, Chu NK, Lin MS, Hu CF. Ultrasound stimulation of types I and III collagen expression of tendon cell and upregulation of transforming growth factor β. J Orthop Res 2006;24:1310-6.
12. O'Brien M. Functional anatomy and physiology of tendons. Clin Sports Med 1992;11:505-20.
13. Leadbetter WB. Cell-matrix response in tendon injury. Clin Sports Med 1992;11:533-77.
14. Minshul J, Pines J, Golsteyn R, Standart N, Mackie S, Colman A, et al. The role of cyclin synthesis, modification and destruction in the control of cell division. J Cell Sci Suppl 1989;12:77-97.
15. Draetta G, Beach D. Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement. Cell 1988;54:17-26.
16. Dulic V, Lees E, Reed SI. Association of human cyclin E with a periodic G1-S phase protein kinase. Science 1992;257:1958-69.
17. Tang J, Erikson RL, Liu X. Checkpoint kinase 1 (Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1). Proc Natl Acad Sci U S A 2006;103:11964-9.
18. Van Vugt MA, Medema RH. Getting in and out of mitosis with Polo-like kinase-1. Oncogene 2005;24:2844-59.
19. Liu X, Erikson RL. Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plkl by SiRNA. Proc Natl Acad Sci U S A 2002;99:8672-6.
20. Ahn J, Urist M, Prives C. The Chk2 protein kinase. DNA Repair (Amst) 2004;3:1039-47.
21. Bergeron MG. The pharmacokinetics and tissue penetration of the fluoroquinolones. Clin Invest Med 1989;12:20-2.
22. Dan M, Golomb J, Gorea A, Braf Z, Berger SA. Concentration of ciprofloxacin in human prostatic tissue after oral administration. Antimicrob Agents Chemother 1986;30:88-9.
23. MacGown AP, White LO, Brown NM, Lovering AM, McMullin CM, Reeves DS. Serum ciprofloxacin concentrations in patients with severe sepsis being treated with ciprofloxacin 200 mg i.v. bd irrespective of renal function. J Antimicrob Chemother 1994;33:1051-4.
24. Shah A, Lettieri J, Kaiser L, Echols R, Heller AH. Comparative pharmacokinetics and safety of ciprofloxacin 400 mg i.v. thrice daily versus 750 mg po twice daily. J Antimicrob Chemother 1994;33:795-801.