Incidence of prolonged prothrombin time in dogs following gastrointestinal decontamination for acute anticoagulant rodenticide ingestion

Journal of Veterinary Emergency and Critical Care

Volumn 18, Issue 3, 2008, Pages 285-291

  Pachtinger, Garret E ^a   Otto, Cynthia M ^a   Syring, Rebecca S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Coagulation; Decontamination; Toxicology; Treatment

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

EID: 45249103946     PISSN: 14793261     EISSN: 14764431     Source Type: Journal    
DOI: 10.1111/j.1476-4431.2008.00313.x     Document Type: Article

References (22)

1. Mount ME. Diagnosis and therapy of anticoagulant rodenticide intoxicants. Vet Clin North Am Small Anim Pract 1988 18 (1) : 115 130.
2. Furie B, Furie BC. Molecular basis of vitamin K-dependent gamma-carboxylation. Blood 1990 75 (9) : 1753 1762.
3. Hellemans J, Vorlat M, Verstraete M. Survival time of prothrombin and factors VII, IX and X after completely synthesis blocking dose of coumarin derivatives. Br J Haematol 1963 9 : 506 512.
4. Hansen N, Beck C. Bilateral hydronephrosis secondary to anticoagulant rodenticide intoxication in a dog. J Vet Emerg Crit Care 2003 13 (12) : 103 107.
5. Peterson J, Streeter V. Laryngeal obstruction secondary to brodifacoum toxicosis in a dog. J Am Vet Med Assoc 1996 208 (3) : 352 354.
6. Waddell L, Poppenga R, Drobatz K. Anticoagulant rodenticide screening in dogs and cats. J Vet Emerg Crit Care 2003 13 (3) : 159 177.
7. Petterino C, Paolo B, Tristo G. Clinical and pathological features of anticoagulant rodenticide intoxications in dogs. Vet Hum Toxicol 2004 46 (2) : 70 75.
8. Petrus DJ, Henik RA. Pericardial effusion and cardiac tamponade secondary to brodifacoum toxicosis in a dog. J Am Vet Med Assoc 1999 215 (5) : 647 648.
9. Hirsh J, Dalen J, Anderson DR, et al. Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest 2001 119 (Suppl. 1) : 8S 21S.
10. Baker RI, Coughlin PB, Gallus AS, et al. Warfarin reversal: consensus guidelines, on behalf of the Australasian Society of Thrombosis and Haemostasis. Med J Aust 2004 181 (9) : 492 497.
11. Caravati EM, Erdman AR, Scharman EJ, et al. Long-acting anticoagulant rodenticide poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol 2007 45 (1) : 1 22.
12. Fiore LD, Scola MA, Cantillon CE, et al. Anaphylactoid reactions to vitamin K. J Thromb Thrombolysis 2001 11 (2) : 175 183.
13. Forbes CD, Thomson C, Prentice CR, et al. Experimental warfarin poisoning in the dog. Platelet function, coagulation and fibrinolysis. J Comp Pathol 1973 83 (2) : 173 180.
14. Woody BJ, Murphy MJ, Ray AC, et al. Coagulopathic effects and therapy of brodifacoum toxicosis in dogs. J Vet Intern Med 1992 6 (1) : 23 28.
15. Johnstone IB. Clinical and laboratory diagnosis of bleeding disorders. Vet Clin North Am Small Anim Pract 1988 18 (1) : 21 33.
16. Mount ME, Feldman BF. Mechanism of diphacinone rodenticide toxicosis in the dog and its therapeutic implications. Am J Vet Res 1983 44 (11) : 2009 2017.
17. Merola V. Anticoagulant rodenticides: deadly for pests, dangerous for pets. Vet Med 2002 97 : 716 722.
18. Bateman SW. Communication in the veterinary emergency setting. Vet Clin North Am Small Anim Pract 2007 37 (1) : 109 121.
19. Cornell KK, Kopcha M. Client-veterinarian communication: skills for client centered dialogue and shared decision making. Vet Clin North Am Small Anim Pract 2007 37 (1) : 37 47.
20. Caravati EM, Erdman AR, Scharman EJ, et al. Long-acting anticoagulant rodenticide poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol 2007 45 (1) : 1 22.
21. Ingels M, Lai C, Tai W, et al. A prospective study of acute, unintentional, pediatric superwarfarin ingestions managed without decontamination. Ann Emerg Med 2002 40 (1) : 73 78.
22. Shepherd G, Klein-Schwartz W, Anderson BD. Acute, unintentional pediatric brodifacoum ingestions. Pediatr Emerg Care 2002 18 (3) : 174 178.