Multimodal HPLC screening of polysaccharide-based chiral stationary phases

Pharmaceutical Technology Europe

Volumn 19, Issue 10, 2007, Pages 59-81

  Huybrechts, Tom ^a   Török, Gabriella ^b   Vennekens, Tom ^b   Sneyers, Rudy ^b   Vrielynck, Sara ^b   Somers, Ivan ^b  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b API Development Analytical Sciences Group   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; GENERIC DRUG; POLYSACCHARIDE; T 1329; T 2399; T 2428; T 2650;

ARTICLE; CHIRAL CHROMATOGRAPHY; CHIRALITY; DRUG DETERMINATION; DRUG INDUSTRY; DRUG STRUCTURE; ENANTIOMER; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; PHASE SEPARATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE;

EID: 45249101458     PISSN: 01646826     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. H. Craner et al., Drug Discov. Today, 9, 105-110 (2004).
2. www.fda.gov/cder/guidance/stereo.htm
3. A.J. Hutt, Smith and Williams' Introduction to the Principles of Drug Design and Action, 4th Edition, in J.H. Smith, Ed. (CRC Press LLC, Boca Raton, FL, USA, 2006), pp 117-183.
4. D.R. Brocks, M. Vakily and R. Mehvar, Chirality in Drug Design and Development, I.K. Reddy and R. Mehvar, Eds. (Marcel Dekker Inc., New York, NY USA, 2004), pp 191-280.
5. V. Farina, et al., Chem. Rev., 106, 2734-2793 (2006).
6. D.A. Pflum et al., OPR&D, 5, 110-115 (2001).
7. G. Gübltz and M.G. Schmid, Biopharm. Drug Dispos., 22, 291-336 (2001).
8. Y. Zhang et al., Drug Discov. Today, 10, 571-577 (2005).
9. M.E. Andersson et al., J. Chromatogr. A, 1005, 83-101 (2003).
10. C Perrin et al., J. Chromatogr. A, 947, 69-83 (2002).
11. C. Perrin et al., J. Chromatogr. A, 966, 119-134 (2002).
12. N. Matthijs et al., J. Chromatogr. A, 1041, 119-133 (2004).
13. A.X. Wang, J.T. Lee and T.E. Beesley, LCGC N. Am., 18, 626-639 (2000).
14. M. Luz de la Puente et al., J. Chromatogr. A, 983, 101-114 (2003).
15. Y. Zhang et al., J. Chromatogr. A, 1049, 75-84 (2004).
16. R Sajonz et al., Chirality, 18, 803-813 (2006).
17. C.J. Welch et al, J. Liq. Chromatogr. Relat. Technol., 29, 2185-2200 (2006).
18. G. Török, et al., J. Pharm. Biomed. Anal., 39, 425-430 (2005).
19. M.I. Jimidar et al., Electrophoresis, 25, 2772-2785 (2004).
20. T.E. Beesley, J.T. Lee and A.X. Wang, Chiral Separation Techniques: A Practical Approach (2nd Ed.), G. Subramanian, Ed. (Wiley-VCH Verlag GmbH, Weinheim, Germany, 2001), pp 25-54.
21. Advanced Separation Technologies Inc. Chirobiotic Handbook: A guide to Using Macrocyclic Glycopeptides Bonded Phases For Chiral LC Separations (5th Ed.) (2004).