Drug design should involve consideration of environmental risk and hazard

Letters in Drug Design and Discovery

Volumn 5, Issue 4, 2008, Pages 232-235

  Gunnarsson, B ^a   Wennmalm, A ^a  

^a STOCKHOLM COUNTY COUNCIL   (Sweden)

Author keywords

Drug legislation; Environment; Hazard assessment; Human drugs; Risk assessment; Sewage water

Indexed keywords

ATENOLOL; CETIRIZINE; CIPROFLOXACIN; CODEINE; DICLOFENAC; FUROSEMIDE; IBUPROFEN; KETOPROFEN; LOSARTAN; METOPROLOL; NAPROXEN; PARACETAMOL; SULFAMETHOXAZOLE; TRAMADOL;

ARTICLE; BIOACCUMULATION; DRUG DEGRADATION; DRUG DESIGN; DRUG LEGISLATION; ECOTOXICITY; ENVIRONMENTAL IMPACT; PRIORITY JOURNAL; RISK ASSESSMENT; SEWAGE; SWEDEN;

EID: 45249098945     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018008784619942     Document Type: Article

References (9)

1. Kümmerer, K. Pharmaceuticals in the Environment, Springer: Berlin, 2004.
2. Purdom, C.E.; Hardiman, P.A.; Bye, V.J.; Eno, N.C.; Tyler, C.R.; Sumpter, J.P. Chem. Ecol., 1994, 8, 265.
3. Larsson, D.G.J.; Adolfsson-Erici, M.; Parkkonen, J.; Pettersson, M.; Berg, H.; Olsson, P.-E.; Förlin, L. Aquatic Toxicology, 1999, 45, 91.
4. Hugget, D.B.; Brooks, B.W.; Peterson, B.; Foran, C.M.; Schlenk, D. Arch. Env. Contamin. Toxicol., 2002, 43, 229.
5. Report from Swedish Medical Products Agency. Miljöpåverkan från läkemedel samt kosmetiska och hygieniska produkter (summary in English), 2004, www.mpa.se
6. www.fass.se The website published by the Swedish Association of the Pharmaceutical Industry.
7. European Medicines Agency. Guideline on the environmental risk assessment of medicinal products for human use.http://www.emea.europa.eu/pdfs/human/swp/ 444700en.pdf.
8. OECD Test Guidelines for Testing of Chemicals (see http://www.oecd.org/).
9. Directive 2004/27/EC of the European Parliament and of the Council of 31 March 2004 amending Directive 2001/83/EC on the Community code relating to medicinal products for human use, http://ec.europa.eu/enterprise/ pharmaceuticals/ eudralex/vol-1/dir_2004_27/dir_2004_27_en.pdf.