Controversies over the role of radiation therapy for ductal carcinoma in situ

Expert Review of Anticancer Therapy

Volumn 8, Issue 3, 2008, Pages 433-441

  Smith, Benjamin D ^a   Smith, Grace L ^a   Buchholz, Thomas A ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Breast cancer; Conservative surgery; DCIS; Ductal carcinoma in situ; Radiation therapy

Indexed keywords

ANTINEOPLASTIC AGENT; TAMOXIFEN;

ADJUVANT THERAPY; CANCER CLASSIFICATION; CANCER GRADING; CANCER GROWTH; CANCER INVASION; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER RISK; CANCER SIZE; CANCER SURVIVOR; CARCINOMA IN SITU; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; EARLY DIAGNOSIS; EVIDENCE BASED MEDICINE; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; INTRADUCTAL CARCINOMA; MAMMOGRAPHY; MEDICARE; METASTASIS POTENTIAL; MULTIMODALITY CANCER THERAPY; OVERALL SURVIVAL; PARTIAL MASTECTOMY; POPULATION RESEARCH; RADIATION DOSE FRACTIONATION; RADIATION HAZARD; RADIATION INJURY; RECURRENCE RISK; RETROSPECTIVE STUDY; REVIEW; RISK REDUCTION; SURGICAL TECHNIQUE; SURVIVAL RATE; TREATMENT FAILURE; UNSPECIFIED SIDE EFFECT;

BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; COMBINED MODALITY THERAPY; FEMALE; HUMANS; MASTECTOMY; NEOPLASM STAGING; PRECANCEROUS CONDITIONS;

EID: 45249093406     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/14737140.8.3.433     Document Type: Review

References (25)

1. Jemal A, Siegel R, Ward E et al. Cancer statistics, 2007. CA Cancer J. Clin. 57(1), 43-66 (2007).
2. Page DL, Dupont WD, Rogers LW, Jensen RA, Schuyler PA. Continued local recurrence of carcinoma 15-25 years after a diagnosis of low grade ductal carcinoma in situ of the breast treated only by biopsy. Cancer 76(7), 1197-1200 (1995).
3. Smith GL, Smith BD, Haffty BG. Rationalization and regionalization of treatment for ductal carcinoma in situ of the breast. Int. J. Radiat. Oncol. Biol. Phys. 65(5), 1397-1403 (2006).
4. Baxter NN, Virnig BA, Durham SB, Turtle TM. Trends in the treatment of ductal carcinoma in situ of the breast. J. Natl. Cancer Inst. 96(6), 443-448 (2004).
5. Katz SJ, Lantz PM, Janz NK et al. Patterns and correlates of local therapy for women with ductal carcinoma-in-situ. J. Clin. Oncol. 23(13), 3001-3007 (2005).
6. Fisher B, Land S, Mamounas E et al. Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the national surgical adjuvant breast and bowel project experience. Semin. Oncol. 28(4), 400-418 (2001).
7. Fisher ER, Dignam J, Tan-Chiu E et al. Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) eight-year update of Protocol B-17: intraductal carcinoma. Cancer 86(3), 429-438 (1999).
8. Bijker N, Meijnen P, Peterse JL et al. Breast-conserving treatment with or without radiotherapy in ductal carcinoma-in-situ: ten-year results of European Organisation for Research and Treatment of Cancer randomized Phase III trial 10853-a study by the EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Group. J. Clin. Oncol. 24(21), 3381-3387 (2006).
9. Emdin SO, Granstrand B, Ringberg A et al. SweDCIS: Radiotherapy after sector resection for ductal carcinoma in situ of the breast. Results of a randomised trial in a population offered mammography screening. Acta Oncol. 45(5), 536-543 (2006).
10. Ringberg A, Nordgren H, Thorstensson S et al. Histopathological risk factors for ipsilateral breast events after breast conserving treatment for ductal carcinoma in situ of the breast-results from the Swedish randomised trial. Eur. J. Cancer 43(2), 291-298 (2007).
11. Houghton J, George WD, Cuzick J et al. Radiotherapy and tamoxifen in women with completely excised ductal carcinoma in situ of the breast in the UK, Australia, and New Zealand: randomised controlled trial. Lancet 362(9378), 95-102 (2003).
12. Viani GA, Stefano EJ, Afonso SL et al. Breast-conserving surgery with or without radiotherapy in women with ductal carcinoma in situ: a meta-analysis of randomized trials. Radiat. Oncol. 2, 28, (2007).
13. Warren JL, Weaver DL, Bocklage T et al. The frequency of ipsilateral second tumors after breast-conserving surgery for DCIS: a population based analysis. Cancer 104(9), 1840-1848 (2005).
14. Smith BD, Haffty BG, Buchholz TA et al. Effectiveness of radiation therapy in older women with ductal carcinoma in situ. J. Natl Cancer Inst. 98(18), 1302-1310 (2006).
15. Silverstein MJ. An argument against routine use of radiotherapy for ductal carcinoma in situ. Oncology (Williston - Park, NY), 17(11), 1511-1533; discussion 1133-1514, 1539, 1542 passim (2003).
16. Clarke M, Collins R, Darby S et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 366(9503), 2087-2106 (2005).
17. Ravdin PM, Siminoff IA, Harvey JA. Survey of breast cancer patients concerning their knowledge and expectations of adjuvant therapy. J. Clin. Oncol. 16(2), 515-521 (1998).
18. Wong JS, Kaelin CM, Troyan SL et al. Prospective study of wide excision alone for ductal carcinoma in situ of the breast. J. Clin. Oncol. 24(7), 1031-1036 (2006).
19. Fisher B, Costantino J, Redmond C et al. Lumpectomy compared with lumpectomy and radiation therapy for the treatment of intraductal breast cancer. N. Engl. J. Med. 328(22), 1581-1586 (1993).
20. Hughes L, Wang M, Page D et al. Five year results of intergroup study E5194: local excision alone (without radiation treatment) for selected patients with ductal carcinoma in situ (DCIS). Presented at: San Antonio Breast Cancer Symposium. San Antonio, TX, USA, 14-17 December (2006).
21. Kerlikowske K, Molinaro A, Cha I et al. Characteristics associated with recurrence among women with ductal carcinoma in situ treated by lumpectomy. J. Natl. Cancer Inst. 95(22), 1692-1702 (2003).
22. Silverstein MJ, Lagios MD, Groshen S et al. The influence of margin width on local control of ductal carcinoma in situ of the breast. N. Engl. J. Med. 340(19), 1455-1461 (1999).
23. Macdonald HR, Silverstein MJ, Lee LA et al. Margin width as the sole determinant of local recurrence after breast conservation in patients with ductal carcinoma in situ of the breast. Am. J. Surg. 192(4), 420-422 (2006).
24. Wong ND, Thakral G, Franklin SS et al. Preventing heart disease by controlling hypertension: impact of hypertensive subtype, stage, age, and sex. Am. Heart J. 145(5), 888-895 (2003).
25. Black DM, Cummings SR, Karpf DB et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348(9041), 1535-1541 (1996).