Limitations of maximum likelihood estimation procedures when a majority of the observations are below the limit of detection

Analytical Chemistry

Volumn 80, Issue 12, 2008, Pages 4767-4772

  Jain, Ram B ^a   Wang, Richard Y ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(P ,P ,T) MEASUREMENTS; CENSORED DATA; DATA SETS; LIKELIHOOD ESTIMATION; LIMIT-OF-DETECTION (LOD); MULTIPLE IMPUTATION; POLYCHLORINATED BIPHENYL (PCB); SAMPLE SIZES; STANDARD DEVIATION (STD);

POLYCHLORINATED BIPHENYL;

ACCURACY; ARTICLE; ASSAY; CHEMISTRY; MAXIMUM LIKELIHOOD METHOD; SIMULATION;

ALBUMINURIA; CHEMISTRY, ANALYTICAL; IRON; LEAD; LIKELIHOOD FUNCTIONS; POLYCHLORINATED BIPHENYLS; SAMPLE SIZE; SENSITIVITY AND SPECIFICITY;

EID: 45249092770     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac8003743     Document Type: Article

References (4)

1. Jain, R. B.; Caudill, S. P.; Wang, R. Y.; Monsel, E. Anal. Chem. 2008, 80, 1124-1132.
2. Lubin, J. H.; Colt, J. S.; Camann, D.; Davis, S.; Cerhan, J. R.; Severson, R. K.; Bernstein, L.; Hartage, P. Environ. Health Perspect. 2004, 112, 1691-1696.
3. Lynn, H. S. Stat. Med. 2001, 20, 33-45.
4. National Center for Health Statistics. http://www.cdc.gov/nchs/about/ major/nhanes/nhanes20032004/lab03_04.htm (accessed Oct 16, 2006).