Recombinant Human Epidermal Growth Factor Accelerates Recovery of Mouse Small Intestinal Mucosa After Radiation Damage

International Journal of Radiation Oncology Biology Physics

Volumn 71, Issue 4, 2008, Pages 1230-1235

  Lee, Kang Kyoo ^a   Jo, Hyang Jeong ^a   Hong, Joon Pio ^b   Lee, Sang wook ^b   Sohn, Jung Sook ^a   Moon, Soo Young ^b   Yang, Sei Hoon ^a   Shim, Hyeok ^a   Lee, Sang Ho ^c   Ryu, Seung Hee ^b   Moon, Sun Rock ^a  

^a Wonkwang University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c Iksan Hospital   (South Korea)

Author keywords

Enteritis; Radiation; Recombinant human epidermal growth factor

Indexed keywords

ANIMAL CELL CULTURE; BIOACTIVITY; ENHANCED RECOVERY; HEALTH; IRRADIATION; MICROFLUIDICS; PEPTIDES; PIGMENTS; RECOVERY;

APPLIED (CO); BALB/C MICE; BODY WEIGHT; CONTROL GROUP (CON); DAMAGE MODELLING; ELSEVIER (CO); EVALUATION METHODS; HIGH DOSE; INTESTINAL MUCOSA; RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR (RHEGF); REGENERATION (RENOVATING); SINGLE DOSE; SURVIVAL RATES; SYSTEMIC ADMINISTRATION;

RADIATION;

RECOMBINANT EPIDERMAL GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIARRHEA; DRUG DOSE INCREASE; INFLAMMATION; INTESTINE INJURY; INTESTINE ULCER; INTESTINE VILLUS; IRRADIATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; SMALL INTESTINE MUCOSA; SURVIVAL RATE;

ANIMALS; CELL PROLIFERATION; EPIDERMAL GROWTH FACTOR; INTESTINAL DISEASES; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; MICE; MICE, INBRED C57BL; RADIATION INJURIES; RADIATION-PROTECTIVE AGENTS; RECOMBINANT PROTEINS; RECOVERY OF FUNCTION; TREATMENT OUTCOME;

EID: 45249088102     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.03.041     Document Type: Article

References (24)

1. Nguyen N.P., Antoine J.E., Dutta S., et al. Current concepts in radiation enteritis and implications for future clinical trials. Cancer 95 (2002) 1151-1163
2. Ooi B.S., Tjandra J.J., and Green M.D. Morbidities of adjuvant chemotherapy and radiotherapy for resectable rectal cancer: An overview. Dis Colon Rectum 42 (1999) 403-418
3. Savage Jr. C.R., Inagami T., and Cohen S. The primary structure of epidermal growth factor. J Biol Chem 247 (1972) 7612-7621
4. Taylor J.M., Mitchell W.M., and Cohen S. Epidermal growth factor. Physical and chemical properties. J Biol Chem 247 (1972) 5928-5934
5. Cohen S. Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J Biol Chem 237 (1962) 1555-1562
6. Cohen S., and Carpenter G. Human epidermal growth factor: Isolation and chemical and biological properties. Proc Natl Acad Sci U S A 72 (1975) 1317-1321
7. Lee S.W., Jung K.I., Kim Y.W., et al. Effect of epidermal growth factor against radiotherapy-induced oral mucositis in rats. Int J Radiat Oncol Biol Phys 67 (2007) 1172-1178
8. Cohen S. The epidermal growth factor (EGF). Cancer 51 (1983) 1787-1791
9. Steidler N.E., and Reade P.C. Histomorphological effects of epidermal growth factor on skin and oral mucosa in neonatal mice. Arch Oral Biol 25 (1980) 37-43
10. Waterfield M.D. Epidermal growth factor and related molecules. Lancet 1 (1989) 1243-1246
11. Weaver L.T., Gonnella P.A., Israel E.J., et al. Uptake and transport of epidermal growth factor by the small intestinal epithelium of the fetal rat. Gastroenterology 98 (1990) 828-837
12. Wong W.M., and Wright N.A. Epidermal growth factor, epidermal growth factor receptors, intestinal growth, and adaptation. JPEN J Parenter Enteral Nutr 23 (1999) S83-S88
13. Chao J.C., Liu K.Y., Chen S.H., et al. Effect of oral epidermal growth factor on mucosal healing in rats with duodenal ulcer. World J Gastroenterol 9 (2003) 2261-2265
14. Potten C.S., and Booth C. The role of radiation-induced and spontaneous apoptosis in the homeostasis of the gastrointestinal epithelium: A brief review. Comp Biochem Physiol B Biochem Mol Biol 118 (1997) 473-478
15. Bamba T., Tsujikawa T., and Hosoda S. Effect of epidermal growth factor by different routes of administration on the small intestinal mucosa of rats fed elemental diet. Gastroenterol Jpn 28 (1993) 511-517
16. Bragg L.E., Hollingsed T.C., and Thompson J.S. Urogastrone reduces gut atrophy during parenteral alimentation. J Parenter Entel Nutr 14 (1990) 283-286
17. Goodlad R.A., Wilson T.J., Lenton W., et al. Urogastrone-epidermal growth factor is trophic to the intestinal epithelium of parenterally fed rats. Experientia 41 (1985) 1161-1163
18. Walker-Smith J.A., Phillips A.D., Walford N., et al. Intravenous epidermal growth factor/urogastrone increases small-intestinal cell proliferation in congenital microvillous atrophy. Lancet 2 (1985) 1239-1240
19. Hamilton I., Sanders S., Hopwood D., et al. Collagenous colitis associated with small intestinal villous atrophy. Gut 27 (1986) 1394-1398
20. Sullivan P.B., Brueton M.J., Tabara Z.B., et al. Epidermal growth factor in necrotising enteritis. Lancet 338 (1991) 53-54
21. Xia L., Yuan Y.Z., Xu C.D., et al. Effects of epidermal growth factor on the growth of human gastric cancer cell and the implanted tumor of nude mice. World J Gastroenterol 8 (2002) 455-458
22. Kubota T., Josui K., Fukutomi T., et al. Growth regulation by estradiol, progesterone and recombinant human epidermal growth factor of human breast carcinoma xenografts grown serially in nude mice. Anticancer Res 15 (1995) 1275-1278
23. Kwok T.T., and Sutherland R.M. Enhancement of sensitivity of human squamous carcinoma cells to radiation by epidermal growth factor. J Natl Cancer Inst 81 (1989) 1020-1024
24. Kwok T.T., and Sutherland R.M. Differences in EGF related radiosensitisation of human squamous carcinoma cells with high and low numbers of EGF receptors. Br J Cancer 64 (1991) 251-254