Depressive symptoms predict heart rate recovery after exercise treadmill testing in patients with coronary artery disease: Results from the psychophysiological investigations of myocardial ischemia study

Psychosomatic Medicine

Volumn 70, Issue 4, 2008, Pages 456-460

  Hughes, Joel W ^a,d   York, Kaki M ^b   Li, Qin ^b   Freedland, Kenneth E ^c   Carney, Robert M ^c   Sheps, David S ^b  

^a KENT STATE UNIVERSITY   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Department of Psychology ^*  (United States)

Author keywords

Autonomic nervous system; Coronary disease; Depression; Heart rate recovery

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; ADRENALIN; CORTICOTROPIN; HYDROCORTISONE; NORADRENALIN;

ADULT; AGED; ARTICLE; BECK DEPRESSION INVENTORY; CORONARY ARTERY DISEASE; DEPRESSION; EXERCISE TEST; FEMALE; HEART RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; SYMPTOM; TREADMILL EXERCISE; ADRENERGIC SYSTEM; AROUSAL; BLOOD; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MAJOR DEPRESSION; MENTAL STRESS; MIDDLE AGED; PATHOPHYSIOLOGY; PERSONALITY TEST; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; RECURRENT DISEASE; REFERENCE VALUE;

ADRENOCORTICOTROPIC HORMONE; AROUSAL; CORONARY DISEASE; DEPRESSIVE DISORDER, MAJOR; EPINEPHRINE; EXERCISE TEST; FEMALE; HEART RATE; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MIDDLE AGED; NOREPINEPHRINE; PERSONALITY INVENTORY; PITUITARY-ADRENAL SYSTEM; RECURRENCE; REFERENCE VALUES; STRESS, PSYCHOLOGICAL; SYMPATHETIC NERVOUS SYSTEM;

EID: 45149121422     PISSN: 00333174     EISSN: 15347796     Source Type: Journal    
DOI: 10.1097/PSY.0b013e31816fcab3     Document Type: Article

References (50)

1. Barefoot JC, Helms MJ, Mark DB, Blumenthal JA, Califf RM, Haney TL, O'Connor CM, Siegler IC, Williams RB. Depression and long-term mortality risk in patients with coronary artery disease. Am J Cardiol 1996;78:613-617
2. Carney RM, Rich MW, Freedland KE, Saini J, teVelde A, Simeone C, Clark K. Major depressive disorder predicts cardiac events in patients with coronary artery disease. Psychosom Med 1988;50:627-633
3. Ahern DK, Gorkin L, Anderson JL, Tierney C, Hallstrom A, Ewart C, Capone RJ, Schron E, Kornfeld D, Herd JA. Biobehavioral variables and mortality or cardiac arrest in the Cardiac Arrhythmia Pilot Study (CAPS). Am J Cardiol 1990;66:59-62.
4. Frasure-Smith N, Lesperance F. Reflections on depression as a cardiac risk factor. Psychosom Med 2005;67(Suppl 1):S19-S25.
5. Frasure-Smith N, Lesperance F, Talajic M. Depression and 18-month prognosis after myocardial infarction. Circulation 1995;91:999-1005.
6. Frasure-Smith N, Lesperance F, Talajic M. Depression following myo-cardial infarction. Impact on 6-month survival. JAMA 1993;270: 1819-1825
7. Lesperance F, Frasure-Smith N. Negative emotions and coronary heart disease: getting to the heart of the matter. [Letter; comment.]. Lancet 1996;347:414-415
8. Lesperance F, Frasure-Smith N, Talajic M, Bourassa MG. Five-year risk of cardiac mortality in relation to initial severity and one-year changes in depression symptoms after myocardial infarction. Circulation 2002;105: 1049-1053
9. Welin C, Lappas G, Wilhelmsen L. Independent importance of psychosocial factors for prognosis after myocardial infarction. J Intern Med 2000;247:629.
10. Grace SL, Abbey SE, Kapral MK, Fang J, Nolan RP, Stewart DE. Effect of depression on five-year mortality after an acute coronary syndrome. Am J Cardiol 2005;96:1179-1185
11. Writing Committee for the ENRICHD Investigators. Effects of treating depression and low perceived social support on clinical events after myocardial infarction: The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. JAMA 2003;289:3106-3116
12. Carney RM, Freedland KE, Rich MW, Jaffe AS. Depression as a risk factor for cardiac events in established coronary heart disease: a review of possible mechanisms. Ann Behav Med 1995;17:142-149
13. Dalack GW, Roose SP. Perspectives on the relationship between cardiovascular disease and affective disorder. J Clin Psychiatry 1990;51:4-11.
14. Carney RM, Freedland KE, Miller GE, Jaffe AS. Depression as a risk factor for cardiac mortality and morbidity: a review of potential mechanisms. J Psychosom Res 2002;53:897-902.
15. Carney RM, Freedland KE, Veith RC. Depression, the autonomic nervous system, and coronary heart disease. Psychosom Med 2005;67(Suppl 1):S29-S33.
16. Carney RM, Saunders RD, Freedland KE, Stein P, Rich MW, Jaffe AS. Association of depression with reduced heart rate variability in coronary artery disease. Am J Cardiol 1995;76:562-564
17. Carney RM, Blumenthal JA, Stein PK, Watkins L, Catellier D, Berkman LF, Czajkowski SM, O'Connor C, Stone PH, Freedland KE. Depression, heart rate variability, and acute myocardial infarction. Circulation 2001; 104:2024-2028
18. Hughes JW, Stoney CM. Depressed mood is related to high-frequency heart rate variability during stressors. Psychosom Med 2000;62: 796-803.
19. Krittayaphong R, Cascio WE, Light KC, Sheffield D, Golden RN, Finkel JB, Glekas G, Koch GG, Sheps DS. Heart rate variability in patients with coronary artery disease: differences in patients with higher and lower depression scores. Psychosom Med 1997;59:231-235
20. Bigger JT, Fleiss JL, Steinman RC, Rolnitzky LM, Klieger RE, Rottman JN. Frequency domain measures of heart period variability and mortality after myocardial infarction. Circulation 1992;85:164-171
21. Klieger RE, Miller JP, Bigger JT, Moss AJ. The Multicenter Post-infarction Research Group. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol 1987;59:256-262
22. La Rovere MT, Bigger JTJ, Marcus FI, Mortara A, Schwartz PJ. Barore-flex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators. Lancet 1998;351: 478-484
23. Carney RM, Blumenthal JA, Freedland KE, Stein P, Howells WB, Berkman LF, Watkins L, Czajkowski SM, Hayano J, Domitrovich PP, Jaffe AS. Low heart rate variability and the effect of depression on post-myocardial infarction mortality. Arch Intern Med 2005;165: 1486-1491
24. Arai Y, Saul JP, Albrecht P, Hartley LH, Lilly LS, Cohen RJ, Colucci WS. Modulation of cardiac autonomic activity during and immediately after exercise. Am J Physiol 1989;256(1 Pt 2):H132-H141.
25. Cole CR, Foody JM, Blackstone EH, Lauer MS. Heart rate recovery after submaximal exercise testing as a predictor of mortality in a cardiovas-cularly healthy cohort. Ann Intern Med 2000;132:552-555
26. Nishime EO, Cole CR, Blackstone EH, Pashkow FJ, Lauer MS. Heart rate recovery and treadmill exercise score as predictors of mortality in patients referred for exercise ECG. JAMA 2000;284:1392-1398
27. Pierpont GL, Stolpman DR, Gornick CC. Heart rate recovery post-exercise as an index of parasympathetic activity. J Auton Nerv Syst 2000;80:169-174
28. Pierpont GL, Voth EJ. Assessing autonomic function by analysis of heart rate recovery from exercise in healthy subjects. Am J Cardiol 2004;94: 64-68
29. Lipinski MJ, Vetrovec GW, Froelicher VF. Importance of the first two minutes of heart rate recovery after exercise treadmill testing in predicting mortality and the presence of coronary artery disease in men. Am J Cardiol 2004;93:445-449
30. Vivekananthan DP, Blackstone EH, Pothier CE, Lauer MS. Heart rate recovery after exercise is a predictor of mortality, independent of the angiographic severity of coronary disease. J Am Coll Cardiol 2003;42: 831-838
31. Cole CR, Blackstone EH, Pashkow FJ, Snader CE, Lauer MS. Heart-rate recovery immediately after exercise as a predictor of mortality. N Engl J Med 1999;341:1351-1357
32. Camerini A. [Heart rate recovery and treadmill exercise score as predictors of mortality in patients referred for exercise ECG]. Ital Heart J Suppl 2001;2:200-202
33. Cheng YJ, Lauer MS, Earnest CP, Church TS, Kampert JB, Gibbons LW, Blair SN. Heart rate recovery following maximal exercise testing as a predictor of cardiovascular disease and all-cause mortality in men with diabetes. Diabetes Care 2003;26:2052-2057
34. Desai MY, Pena-Almaguer E, Mannting F. Abnormal heart rate recovery after exercise: a comparison with known indicators of increased mortality. Cardiology 2001;96:38-44.
35. Diaz LA, Brunken RC, Blackstone EH, Snader CE, Lauer MS. Independent contribution of myocardial perfusion defects to exercise capacity and heart rate recovery for prediction of all-cause mortality in patients with known or suspected coronary heart disease. J Am Coll Cardiol 2001;37: 1558-1564
36. Nissinen SI, Makikallio TH, Seppanen T, Tapanainen JM, Salo M, Tulppo MP, Huikuri HV. Heart rate recovery after exercise as a predictor of mortality among survivors of acute myocardial infarction. Am J Cardiol 2003;91:711-714
37. Watanabe J, Thamilarasan M, Blackstone EH, Thomas JD, Lauer MS. Heart rate recovery immediately after treadmill exercise and left ventricular systolic dysfunction as predictors of mortality: the case of stress echocardiography. Circulation 2001;104:1911-1916
38. Jouven X, Empana JP, Schwartz PJ, Desnos M, Courbon D, Ducimetiere P. Heart-rate profile during exercise as a predictor of sudden death. N Engl J Med 2005;352:1951-1958 (Pubitemid 40638365)
39. Hughes JW, Casey E, Luyster F, Doe VH, Waechter D, Rosneck J, Josephson R. Depression symptoms predict heart rate recovery after treadmill stress testing. Am Heart J 2006;151:1122.
40. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961;4:561-571
41. Kaufmann PG, McMahon RP, Becker LC, Bertolet B, Bonsall R, Chai-tman B, Cohen JD, Forman S, Goldberg AD, Freedland K, Ketterer MW, Krantz DS, Pepine CJ, Raczynski J, Stone PH, Taylor H, Knatterud GL, Sheps DS. The Psychophysiological Investigations of Myocardial Ischemia (PIMI) study: objective, methods, and variability of measures. Psychosom Med 1998;60:56-63.
42. Pepine CJ, Geller NL, Knatterud GL, Bourassa MG, Chaitman BR, Davies RF, Day P, Deanfield JE, Goldberg AD, McMahon RP. The Asymptomatic Cardiac Ischemia Pilot (ACIP) study: design of a randomized clinical trial, baseline data and implications for a long-term outcome trial. J Am Coll Cardiol 1994;24:1-10.
43. Tamesis B, Stelken A, Byers S, Shaw L, Younis L, Miller DD, Chaitman BR. Comparison of the Asymptomatic Cardiac Ischemia Pilot and modified Asymptomatic Cardiac Ischemia Pilot versus Bruce and Cornell exercise protocols. Am J Cardiol 1993;72:715-720
44. Hollenberg M, Haight T, Tager IB. Depression decreases cardiorespira-tory fitness in older women. J Clin Epidemiol 2003;56:1111-1117
45. Tager IB, Hollenberg M, Satariano WA. Association between self-reported leisure-time physical activity and measures of cardiorespiratory fitness in an elderly population. Am J Epidemiol 1998;147:921-931
46. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 1996;93:1043-1065
47. Ruo B, Rumsfeld JS, Pipkin S, Whooley MA. Relation between depressive symptoms and treadmill exercise capacity in the Heart and Soul Study. Am J Cardiol 2004;94:96-99
48. Bonnet F, Irving K, Terra JL, Nony P, Berthezene F, Moulin P. Anxiety and depression are associated with unhealthy lifestyle in patients at risk of cardiovascular disease. Atherosclerosis 2005;178:339-344
49. Carnethon MR, Jacobs DRJ, Sidney S, Sternfeld B, Gidding SS, Shoush-tari C, Liu K. A longitudinal study of physical activity and heart rate recovery: CARDIA, 1987-1993. Med Sci Sports Exerc 2005;37:606-612
50. Lind L, Andren B. Heart rate recovery after exercise is related to the insulin resistance syndrome and heart rate variability in elderly men. Am Heart J 2002;144:666-672