Should randomized clinical trials be required for proton radiotherapy? An alternative view

Journal of Clinical Oncology

Volumn 26, Issue 15, 2008, Pages 2438-2439

  Glatstein, Eli ^a   Glick, John ^a   Kaiser, Larry ^a   Hahn, Stephen M ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTON;

CANCER CONTROL; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; DATA ANALYSIS; HUMAN; INTERMETHOD COMPARISON; MEDICAL ETHICS; MEDICAL TECHNOLOGY; METASTASIS; MULTIMODALITY CANCER THERAPY; NOTE; PHOTON; PRIORITY JOURNAL; PROTON THERAPY; RADIATION DOSE DISTRIBUTION; RANDOMIZED CONTROLLED TRIAL; NEOPLASM;

HUMANS; NEOPLASMS; PROTONS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 45149103248     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2008.17.1843     Document Type: Note

References (12)

1. Goitein M, Cox JD: Should randomized clinical trials be required for proton radiotherapy? J Clin Oncol 26:175-176, 2008
2. Brada M, Pils-Johannesma M and DeRuys-Scher D: Proton therapy in clinical practice: Current clinical evidence. J Clin Oncol 25:965-970, 2007
3. Hall EJ: Intensity-modulated radiation therapy, protons and the risk of second cancers. Int J Radiat Oncol Biol Phys 65:1-7, 2006
4. Overgaard M, Hansen PS, Overgaard J, et al: Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. N Engl J Med 337:949-955, 1997
5. Ragaz J, Jackson SM, Le N, et al: Adjuvant radiotherapy and chemotherapy in node-positive premenopausal women with breast cancer. N Engl J Med 337:956-962, 1997
6. Dillman RO, Seagren SL, Propert KJ, et al: A randomized trial of induction chemotherapy plus high-dose radiation versus radiation alone in stage III non-small-cell lung cancer. N Engl J Med 323:940-945, 1990
7. Schaake-Koning C, van den Bogaert W, Dalesio O, et al: Effects of concomitant cisplatin and radiotherapy on inoperable non-small-cell lung cancer. N Engl J Med 326:524-530, 1992
8. Brizel DM, Albers ME, Fisher SR, et al: Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med 338:1798-1804, 1998
9. Bonner JA, Harari PM, Giralt J, et al: Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354:567-578, 2006
10. Tattersall MH, Lorvidhaya V, Vootiprux V, et al: Randomized trial of epirubicin and cisplatin chemotherapy followed by pelvic radiation in locally advance cervical cancer: Cervical Cancer Study Group of the Asian Oceanian Clinical Oncology Association. J Clin Oncol 13:444-451, 1995
11. Wolmark N, Wieand HS, Hyanes DM, et al: Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-0. J Natl Cancer Inst 92:388-396, 2000
12. Jagsi R, DeLaney TF, Donelan K, et al: Real-time rationing of scarce resources: The Northeast Proton Therapy Center experience. J Clin Oncol 22:2246-2250, 2004