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Volumn 104, Issue 3, 2008, Pages 701-709

Regulation of HMG-CoA reductase expression by hypoxia

Author keywords

HepG2; HIF 1 ; HMG CoAR; Hypoxia; SCAP

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

EID: 45149095195     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21757     Document Type: Article
Times cited : (46)

References (30)
  • 1
    • 0033599028 scopus 로고    scopus 로고
    • Transport-dependent proteolysis of SREBP: Relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi
    • DeBose-Boyd RA, Brown MS, Li WP, Nohturfft A, Goldstein JL, Espenshade PJ. 1999. Transport-dependent proteolysis of SREBP: Relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi. Cell 99:703-712.
    • (1999) Cell , vol.99 , pp. 703-712
    • DeBose-Boyd, R.A.1    Brown, M.S.2    Li, W.P.3    Nohturfft, A.4    Goldstein, J.L.5    Espenshade, P.J.6
  • 3
    • 0021856440 scopus 로고
    • Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme
    • Gil G, Faust JR, Chin DJ, Goldstein JL, Brown MS. 1985. Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme. Cell 41:249-258.
    • (1985) Cell , vol.41 , pp. 249-258
    • Gil, G.1    Faust, J.R.2    Chin, D.J.3    Goldstein, J.L.4    Brown, M.S.5
  • 5
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris AL. 2002. Hypoxia - A key regulatory factor in tumour growth. Nat Rev Cancer 2:38-47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 6
    • 33745138232 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia-inducible factor 1
    • Hirota K, Semenza GL. 2006. Regulation of angiogenesis by hypoxia-inducible factor 1. Crit Rev Oncol Hematol 59:15-26.
    • (2006) Crit Rev Oncol Hematol , vol.59 , pp. 15-26
    • Hirota, K.1    Semenza, G.L.2
  • 7
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton JD, Goldstein JL, Brown MS. 2002. SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109:1125-1131.
    • (2002) J Clin Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 11
    • 0021913335 scopus 로고
    • Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum
    • Liscum L, Finer-Moore J, Stroud RM, Luskey KL, Brown MS, Goldstein JL. 1985. Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum. J Biol Chem 260:522-530.
    • (1985) J Biol Chem , vol.260 , pp. 522-530
    • Liscum, L.1    Finer-Moore, J.2    Stroud, R.M.3    Luskey, K.L.4    Brown, M.S.5    Goldstein, J.L.6
  • 12
    • 0033565672 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity
    • Lisztwan J, Imbert G, Wirbelauer C, Gstaiger M, Krek W. 1999. The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity. Genes Dev 13:1822-1833.
    • (1999) Genes Dev , vol.13 , pp. 1822-1833
    • Lisztwan, J.1    Imbert, G.2    Wirbelauer, C.3    Gstaiger, M.4    Krek, W.5
  • 14
    • 0035887011 scopus 로고    scopus 로고
    • FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
    • Mahon PC, Hirota K, Semenza GL. 2001. FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev 15:2675-2686.
    • (2001) Genes Dev , vol.15 , pp. 2675-2686
    • Mahon, P.C.1    Hirota, K.2    Semenza, G.L.3
  • 15
    • 0025098813 scopus 로고
    • Effects of hypoxia on sterol synthesis, acyl-CoA:cholesterol acyltransferase activity, and efflux of cholesterol in cultured rabbit skin fibroblasts
    • Mukodani J, Ishikawa Y, Fukuzaki H. 1990. Effects of hypoxia on sterol synthesis, acyl-CoA:cholesterol acyltransferase activity, and efflux of cholesterol in cultured rabbit skin fibroblasts. Arteriosclerosis 10:106-110.
    • (1990) Arteriosclerosis , vol.10 , pp. 106-110
    • Mukodani, J.1    Ishikawa, Y.2    Fukuzaki, H.3
  • 16
    • 34848866023 scopus 로고    scopus 로고
    • Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of Insigs
    • Nguyen AD, McDonald JG, Bruick RK, DeBose-Boyd RA. 2007. Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of Insigs. J Biol Chem 282:27436-27446.
    • (2007) J Biol Chem , vol.282 , pp. 27436-27446
    • Nguyen, A.D.1    McDonald, J.G.2    Bruick, R.K.3    DeBose-Boyd, R.A.4
  • 17
    • 0033613126 scopus 로고    scopus 로고
    • Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi
    • Nohturfft A, DeBose-Boyd RA, Scheek S, Goldstein JL, Brown MS. 1999. Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi. Proc Natl Acad Sci USA 96:11235-11240.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11235-11240
    • Nohturfft, A.1    DeBose-Boyd, R.A.2    Scheek, S.3    Goldstein, J.L.4    Brown, M.S.5
  • 19
    • 33846870322 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor-1alpha as a cancer therapy target
    • Patiar S, Harris AL. 2006. Role of hypoxia-inducible factor-1alpha as a cancer therapy target. Endocr Relat Cancer 13 (Suppl 1):S61-S75.
    • (2006) Endocr Relat Cancer , vol.13 , Issue.SUPPL. 1
    • Patiar, S.1    Harris, A.L.2
  • 20
    • 0033215204 scopus 로고    scopus 로고
    • Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein
    • Rawson RB, DeBose-Boyd R, Goldstein JL, Brown MS. 1999. Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein. J Biol Chem 274:28549-28556.
    • (1999) J Biol Chem , vol.274 , pp. 28549-28556
    • Rawson, R.B.1    DeBose-Boyd, R.2    Goldstein, J.L.3    Brown, M.S.4
  • 21
    • 33846475535 scopus 로고    scopus 로고
    • De novo cholesterol synthesis at the crossroads of adaptive response to extracellular stress through SREBP
    • Robichon C, Dugail I. 2007. De novo cholesterol synthesis at the crossroads of adaptive response to extracellular stress through SREBP. Biochimie 89:260-264.
    • (2007) Biochimie , vol.89 , pp. 260-264
    • Robichon, C.1    Dugail, I.2
  • 22
    • 0034901463 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
    • Semenza GL. 2001. Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology. Trends Mol Med 7:345-350.
    • (2001) Trends Mol Med , vol.7 , pp. 345-350
    • Semenza, G.L.1
  • 23
    • 33747621613 scopus 로고    scopus 로고
    • Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1
    • Semenza GL. 2006. Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1. Exp Physiol 91:803-806.
    • (2006) Exp Physiol , vol.91 , pp. 803-806
    • Semenza, G.L.1
  • 24
    • 0037245750 scopus 로고    scopus 로고
    • Accelerated degradation of HMG CoA reductase mediated by binding of Insig-1 to its sterol-sensing domain
    • Sever N, Yang T, Brown MS, Goldstein JL, DeBose-Boyd RA. 2003. Accelerated degradation of HMG CoA reductase mediated by binding of Insig-1 to its sterol-sensing domain. Mol Cell 11:25-33.
    • (2003) Mol Cell , vol.11 , pp. 25-33
    • Sever, N.1    Yang, T.2    Brown, M.S.3    Goldstein, J.L.4    DeBose-Boyd, R.A.5
  • 25
    • 34249982595 scopus 로고    scopus 로고
    • YC-1 inhibits HIF-1 expression in prostate cancer cells: Contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia
    • Sun HL, Liu YN, Huang YT, Pan SL, Huang DY, Guh JH, Lee FY, Kuo SC, Teng CM. 2007. YC-1 inhibits HIF-1 expression in prostate cancer cells: Contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia. Oncogene 26:3941-3951.
    • (2007) Oncogene , vol.26 , pp. 3941-3951
    • Sun, H.L.1    Liu, Y.N.2    Huang, Y.T.3    Pan, S.L.4    Huang, D.Y.5    Guh, J.H.6    Lee, F.Y.7    Kuo, S.C.8    Teng, C.M.9
  • 27
    • 0035918213 scopus 로고    scopus 로고
    • Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP
    • Yamashita K, Discher DJ, Hu J, Bishopric NH, Webster KA. 2001. Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP. J Biol Chem 276:12645-12653.
    • (2001) J Biol Chem , vol.276 , pp. 12645-12653
    • Yamashita, K.1    Discher, D.J.2    Hu, J.3    Bishopric, N.H.4    Webster, K.A.5
  • 28
    • 34547180418 scopus 로고    scopus 로고
    • Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1alpha accumulation and VEGF expression
    • Yeh WL, Lu DY, Lin CJ, Liou HC, Fu WM. 2007. Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1alpha accumulation and VEGF expression. Mol Pharmacol 72:440-449.
    • (2007) Mol Pharmacol , vol.72 , pp. 440-449
    • Yeh, W.L.1    Lu, D.Y.2    Lin, C.J.3    Liou, H.C.4    Fu, W.M.5
  • 29
    • 38349047967 scopus 로고    scopus 로고
    • Maleate Nephrotoxicity: Mechanisms of injury and correlates with ischemic/hypoxic tubular cell death
    • Zager RA, Johnson AC, Naito M, Bomsztyk K. 2007. Maleate Nephrotoxicity: Mechanisms of injury and correlates with ischemic/hypoxic tubular cell death. Am J Physiol Renal Physiol 294:F187-F197.
    • (2007) Am J Physiol Renal Physiol , vol.294
    • Zager, R.A.1    Johnson, A.C.2    Naito, M.3    Bomsztyk, K.4
  • 30
    • 33847164484 scopus 로고    scopus 로고
    • Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells
    • Zhao Q, Du J, Gu H, Teng X, Zhang Q, Qin H, Liu N. 2008. Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells. Pancreas 34:242-247.
    • (2008) Pancreas , vol.34 , pp. 242-247
    • Zhao, Q.1    Du, J.2    Gu, H.3    Teng, X.4    Zhang, Q.5    Qin, H.6    Liu, N.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.