Metabolic stability screen for drug discovery using cassette analysis and column switching.

Drug metabolism letters

Volumn 1, Issue 1, 2007, Pages 67-72

  Halladay, Jason S ^a   Wong, Susan ^a   Jaffer, Sharmin M ^a   Sinhababu, Achintya K ^a   Khojasteh Bakht, S Cyrus ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DRUG;

ANIMAL; ARTICLE; DRUG DEVELOPMENT; ENZYMOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIVER CELL; LIVER MICROSOME; METABOLISM; METHODOLOGY; TANDEM MASS SPECTROMETRY; TIME;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DRUG DISCOVERY; HEPATOCYTES; HUMANS; MICROSOMES, LIVER; PHARMACEUTICAL PREPARATIONS; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 45149093718     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231207779814364     Document Type: Article

References (0)