Quantification of dopaminergic neurotransmission SPECT studies with 123I-labelled radioligands. A comparison between different imaging systems and data acquisition protocols using Monte Carlo simulation

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 35, Issue 7, 2008, Pages 1334-1342

  Crespo, Cristina ^a   Gallego, Judith ^b,c   Cot, Albert ^a,b   Falcón, Carles ^a,d   Bullich, Santiago ^e   Pareto, Deborah ^d,f   Aguiar, Pablo ^a   Sempau, Josep ^b,d   Lomeña, Francisco ^g   Calviño, Francisco ^b   Pavía, Javier ^d,g   Ros, Domènec ^a,d  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

^c INSTITUTE FOR BIOENGINEERING OF CATALONIA IBEC   (Spain)

^d BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^e HOSPITAL DEL MAR   (Spain)

^f Barcelona Biomedical Research Park   (Spain)

^g INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

Brain SPECT; Monte Carlo methods; Receptor imaging; Reconstruction quantification; SPECT instrumentation and algorithms

Indexed keywords

DOPAMINE TRANSPORTER; IODINE 123; RADIOLIGAND;

ANALYTICAL ERROR; ARTICLE; COLLIMATOR; DOPAMINE RELEASE; DOPAMINERGIC ACTIVITY; DOPAMINERGIC TRANSMISSION; IMAGE RECONSTRUCTION; IMAGING SYSTEM; INTERMETHOD COMPARISON; ISOTOPE LABELING; MATHEMATICAL ANALYSIS; MONTE CARLO METHOD; NEUROTRANSMISSION; NONHUMAN; PARTIAL VOLUME EFFECT; QUANTITATIVE ANALYSIS; SIMULATION; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STANDARDIZATION; THREE DIMENSIONAL IMAGING;

ALGORITHMS; BRAIN; DOPAMINE; HUMANS; IMAGING, THREE-DIMENSIONAL; IODINE RADIOISOTOPES; LIGANDS; MONTE CARLO METHOD; PARKINSON DISEASE; PHANTOMS, IMAGING; SYNAPTIC TRANSMISSION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 45049086946     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-007-0711-z     Document Type: Article

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