Oral verapamil effectively suppressed complex ventricular arrhythmias and unmasked U waves in a patient with Andersen-Tawil syndrome

Journal of Electrocardiology

Volumn 41, Issue 4, 2008, Pages 325-328

  Erdogan, Okan ^a   Aksoy, Alper ^b   Turgut, Nilda ^b   Durusoy, Elcim ^b   Samsa, Murat ^b   Altun, Armagan ^b  

^a MARMARA UNIVERSITY   (Turkey)

^b TRAKYA UNIVERSITY   (Turkey)

Author keywords

Andersen Tawil; Bidirectional VT; Long QT; Sudden death; Therapy; U wave; Verapamil

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; PROPAFENONE; SOTALOL; VERAPAMIL;

ADULT; ANDERSEN SYNDROME; ARTICLE; CARDIAC PATIENT; CASE REPORT; DRUG EFFICACY; FACE DYSMORPHIA; FEMALE; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE TACHYCARDIA; HUMAN; PERIODIC PARALYSIS; PRIORITY JOURNAL; TREADMILL EXERCISE;

ADMINISTRATION, ORAL; AGED; ANDERSEN SYNDROME; ANTI-ARRHYTHMIA AGENTS; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; TACHYCARDIA, VENTRICULAR; TREATMENT OUTCOME; VERAPAMIL;

EID: 45049086401     PISSN: 00220736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jelectrocard.2008.02.023     Document Type: Article

References (8)

1. Venance S.L., Cannon S.C., Failho D., et al. The primary periodic paralyses: diagnosis, pathogenesis and treatment. Brain 129 (2006) 8
2. Zhang L., Benson D.W., Tristani-Firouzi M., et al. Electrocardiographic features in Andersen-Tawil syndrome patients with KCNJ2 mutations: characteristic T-U-wave patterns predict the KCNJ2 genotype. Circulation 111 (2005) 2720
3. Tristani-Firouzi M., Jensen J.L., Donaldson M.R., et al. Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome). J Clin Invest 110 (2002) 381
4. Chun T.O., Epstein M.R., Dick M., et al. Polymorphic ventricular tachycardia and KCNJ2 mutations. Heart Rhythm 1 (2004) 235
5. Peters S., Schulze-Bahr E., Etheridge S.P., and Tristani-Firouzi M. Sudden cardiac death in Andersen-Tawil syndrome. Europace 9 (2007) 162
6. Efremidis M., Pappas L.K., Sideris A., Letsas K.P., Gavrielatos G.D., and Kardaras F. Swimming-triggered aborted sudden cardiac death in a patient with Andersen-Tawil syndrome. Int J Cardiol 112 (2006) e45
7. Kannankeril P.J., Roden D.M., and Fish F.A. Suppression of bidirectional ventricular tachycardia and unmasking of prolonged QT interval with verapamil in Andersen's syndrome. J Cardiovasc Electrophysiol 15 (2004) 119
8. Smith A.H., Fish F.A., and Kannankeril P.J. Andersen-Tawil syndrome. Indian Pacing Electrophysiol J 6 (2006) 32