Investigation for the leptin 1 and LEP G2548A gene polymorphism in psoriasis

European Journal of Dermatology

Volumn 18, Issue 3, 2008, Pages 343-344

  Senturk, Nilgun ^a   Aydin, Fatma ^a   Birinci, Asuman ^a   Yuksel, Esra P ^a   Kara, Nurten ^a   Canturk, Tayyar ^a   Durupinar, Belma ^a   Bek, Yüksel ^a   Turanli, Ahmet Y ^a  

^a ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN;

ADULT; BODY MASS; CELLULAR IMMUNITY; DISEASE ACTIVITY; DNA POLYMORPHISM; FEMALE; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; IMMUNE FUNCTION TEST; IMMUNE RESPONSE; LETTER; MALE; NORMAL HUMAN; OBESITY; PSORIASIS; RISK FACTOR;

ADULT; BODY MASS INDEX; CASE-CONTROL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HUMANS; LEPTIN; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PSORIASIS; TURKEY;

EID: 44949252107     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: 10.1684/ejd.2008.0403     Document Type: Letter

References (6)

1. Otero M, Lago R, Gomez R, et al. Towards a pro-inflammatory and immunomodulatory emerging role of leptin. Rheumatology (Oxford) 2006; 45: 944-50.
2. Evereklioglu C, Inaloz HS, Kirtak N, et al. Serum leptin concentration is increased in patients with Behcet's syndrome and is correlated with disease activity. Br J Dermatol 2002; 147: 331-6.
3. Hoffstedt J, Eriksson P, Mottagui-TAbar S, Arner P. A polymorphism in the leptin promoter region (-2548 G/A) influences gene expression and adipose tissue secretion of leptin. Horm Metab Res 2002; 34: 355-9.
4. Mammes O, Betoulle D, Aubert R, et al. Association of the G-2548A polymorphism in the 5′ region of the LEP gene with overweight. Ann Hum Genet 2000; 64: 391-4.
5. Aydin F, Kara N, Senturk N, et al. Lack of association between leptin G2548A gene polymorphism and Behcet's disease. J Eur Acad Dermatol Venereol 2007; 21: 68-71.
6. Kara N, Aydin F, Senturk N, et al. Lack of association between the g-2548a polymorphism of the leptin gene with psoriasis in a Turkish population. (Accepted for publication in Int J Dermatol).