Prophylactic antibiotics to reduce morbidity and mortality in ventilated newborn infants

Cochrane Database of Systematic Reviews

Volumn , Issue 3, 2007, Pages

  Inglis, Garry D T ^a   Jardine, L A ^b   Davies, M W ^b   Inglis, G ^b  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b NONE

Author keywords

*Antibiotic prophylaxis; Humans; Infant, newborn; Respiration, artificial *adverse effects; mortality ; Respiratory tract infections mortality; prevention control

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; CEPHALOSPORIN DERIVATIVE; ERYTHROMYCIN; GENTAMICIN; MACROLIDE; METICILLIN; NAFCILLIN; PENICILLIN DERIVATIVE; PENICILLIN G;

ANTIBIOTIC PROPHYLAXIS; ARTIFICIAL VENTILATION; BACTERIAL COLONIZATION; CHRONIC LUNG DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; HUMAN; INFECTION; INFECTION RISK; META ANALYSIS; NEWBORN; REVIEW; SEPTICEMIA; SYSTEMATIC REVIEW;

EID: 44949236203     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD004338.pub3     Document Type: Review

References (17)

1. Harris 1976 {published data only} Harris H, Wirtschafter D, Cassady G. Endotracheal intubation and its relationship to bacterial colonization and systemic infection of newborn infants. Pediatrics 1976;56:816-23.
2. Lyon 1998 {published data only} Lyon AJ, McColm J, Middlemist L, Fergusson S, McIntosh N, Ross PW. Randomised trial of erythromycin on the development of chronic lung disease in preterm infants. Archives of Disease in Childhood Fetal and Neonatal Edition 1998;78:F10-F14.
3. Adhikari 1996 Adhikari M, Wesley AG, Fourie PB. Intravenous immunoglobulin prophylaxis in neonates on artificial ventilation. South African Medical Journal 1996;86:542-5.
4. Brown 1996 Brown OE, Manning SC. Microbial flora of the subglottis in intubated pediatric patients. International Journal of Pediatric Otorhinolaryngology 1996;35:97-105.
5. Jonsson 1998 Jónsson B, Rylander M, Faxelius G. Ureaplasma urealyticum, erythromycin and respiratory morbidity in high-risk preterm neonates. Acta Pædiatrica 1998;87:1079-84.
6. Kicklighter 2001 Kicklighter SD, Springer SC, Cox T, Hulsey TC, Turner RB. Fluconazole for prophylaxis against candidal rectal colonization in the very low birth weight infant. Pediatrics 2001;107:293-8.
7. Krishnan 1995 Krishnan L, Nasruddin, Prabhakar P, Bhaskaranand N. Routine antibiotic cover for newborns intubated for aspirating meconium: is ti necessary?. Indian Pediatrics 1995;32:529-31.
8. Mandelli 1989 Mandelli M, Mosconi P, Langer M, Cigada M. Prevention of pneumonia in an intensive care unit: a randomized multicenter clinical trial. Critical Care Medicine 1989;17:501-5.
9. Papoff 1997 Papoff P, Fiorucci P, Ficuccilli F, Giustiniani D, Mancuso M, Lorusso G, et al.Characteristics of airway colonization in mechanically ventilated newborn infants [Le caratteristiche della colonizzazione delle vie aeree nel neonato ventilato meccanicamente]. Pediatria Medica e Chirurgica 1997;19:413-6.
10. Cordero 2000 Cordero L, Sananes M, Ayers LW. Failure of systemic antibiotics to eradicate gram-negative bacilli from the airway of mechanically ventilated very low-birth-weight infants. American Journal of Infection-Control 2000;28:286-90.
11. da Silva 1999 da Silva O, Stevens D. Complications of airway management in very-low-birth-weight infants. Biology of the Neonate 1999;75:40-5.
12. Dear 1999 Dear P. Infection in the newborn. In: RennieJM, RobertonNRC editor(s). Textbook of Neonatology. 3rd Edition. Edinburgh: Churchill Livingstone, 1999:1109-1202.
13. Friedland 2001 Friedland DR, Rothschild MA, Delgado M, Isenberg H, Holzman I. Bacterial colonization of endotracheal tubes in intubated neonates. Archives of Otolaryngology - Head & Neck Surgery 2001;127:525- 8.
14. Greenough 1999 Greenough A, Roberton NRC. Acute respiratory disease in the newborn. In: RennieJM, RobertonNRC editor(s). Textbook of Neonatology. 3rd Edition. Edinburgh: Churchill Livingstone, 1999:481-607.
15. Pellinen 1983 Pellinen TJ, Valtonen VV, Luomanmaki K, Sivonen A, Virtanen KS. The microbial colonization due to medical devices in intensive care patients with special emphasis on Candida albicans. Annals of Clinical Research 1983;15:62-5.
16. Rubenstein 1992 Rubenstein JS, Kabat K, Shulman ST, Yogev R. Bacterial and fungal colonization of endotracheal tubes in children: a prospective study. Critical Care Medicine 1992;20:1544-9.
17. Inglis 2004 Inglis GD, Davies MW. Prophylactic antibiotics to reduce morbidity and mortality in ventilated newborn infants. Cochrane Database of Systematic Reviews 2004, Issue 1.Art. No.: CD004338. DOI:10.1002/14651858.CD004338.pub3.