Importance of surgical margins in the management of renal cell carcinoma

Nature Clinical Practice Urology

Volumn 5, Issue 6, 2008, Pages 308-317

  Lam, John S ^a   Bergman, Jonathan ^a   Breda, Alberto ^a   Schulam, Peter G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT;

ANGIOMYOLIPOMA; ARTIFICIAL EMBOLISM; CANCER ADJUVANT THERAPY; CANCER GRADING; CANCER IMMUNOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLAMP; COLD SCISSOR; ENUCLEATION; FROZEN SECTION; HISTOPATHOLOGY; HUMAN; INTRAOPERATIVE PERIOD; KIDNEY CARCINOMA; KIDNEY PARENCHYMA; KIDNEY SURGERY; LAPAROSCOPIC SURGERY; LUNG METASTASIS; MALIGNANT TRANSFORMATION; NEPHRECTOMY; PARTIAL NEPHRECTOMY; PATIENT MONITORING; PEROPERATIVE ECHOGRAPHY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; RADIATION INJURY; RECURRENCE RISK; RECURRENT CANCER; REVIEW; RISK FACTOR; RISK REDUCTION; SURGICAL EQUIPMENT; SURGICAL TECHNIQUE; SURVIVAL RATE; SURVIVAL TIME; TUMOR LOCALIZATION;

CARCINOMA, RENAL CELL; HUMANS; KIDNEY NEOPLASMS; NEPHRECTOMY; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 44949229333     PISSN: 17434270     EISSN: 17434289     Source Type: Journal    
DOI: 10.1038/ncpuro1121     Document Type: Review

References (67)

1. Parkin DM et al. (2005) Global cancer statistics, 2002. CA Cancer J Clin 55:74-108
2. Breda A et al. (2007) Patterns of recurrence and surveillance strategies for renal cell carcinoma following surgical resection. Expert Rev Anticancer Ther 7:847-862
3. Hafez KS et al. (1999) Nephron sparing surgery for localized renal cell carcinoma: Impact of tumor size on patient survival, tumor recurrence and TNM staging. J Urol 162:1930-1933
4. Patard JJ et al. (20(g) Safety and efficacy of partial nephrectomy for all T1 tumors based on an international multicenter experience. J Urol 171: 2181-2185
5. Leibovich BC et al. (2004) Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy. J Urol 171: 1066-1070
6. Thrasher JB et al. (1994) Expanding indications for conservative renal surgery in renal cell carcinoma. Urology 48:160-168
7. Robson CJ et al. (1969) The results of radical nephrectomy for renal cell carcinoma. J Urol 101: 297-301
8. Lam JS et al. (2004) Changing concepts in the surgical management of renal call carcinoma. Eur Urol 45: 692-705
9. Clayman RV et al. (1991) Laparoscopic nephrectomy. N Engl J Med 324:1370-1371
10. Kavoussi LR et al. (1993) Laparoscopic nephrectomy for renal neoplasms. Urology 42: 603-609
11. Dunn MD et al. (2000) Laparoscopic versus open radical nephrectomy: A 9-year experience. J Urol 164: 1153-1159
12. Wells S (1884) Successful removal of two solid circumrenal tumors. BMJ 1: 758
13. Fergany AF et al. (2000) Long-term results of nephron sparing surgery for localized renal cell carcinoma: 10-year followup. J Urol 163: 442-445
14. Ficarra V et al. (2004) Application of TNM, 2002 version, in localized renal cell carcinoma: Is it able to predict different cancer-specific survival probability? Urology 63:1050-1054
15. Becker F et al. (2005) Elective nephron sparing surgery should become standard treatment for small unilateral renal cell carcinoma: long-term survival data at 216 patients. Eur Urol 49: 308-313
16. Patard JJ et al. (2007) Morbidity and clinical outcome of nephron-sparing surgery in relation to tumour size and indication. Eur Urol 52:148-154
17. Gill IS et al. (2003) Comparative analysis of laparoscopic versus open partial nephrectomy for renal tumors in 200 patients. J Urol 170: 64-68
18. Allaf ME et al. (2004) Laparoscopic partial nephrectomy: evaluation of long-term oncological outcome. J Urol 172 871-873
19. Porpiglia F et al. (2005) Assessment of surgical margins in renal cell carcinoma Lfter nephron sparing: A comparative study: laparoscopy vs open surgery. J Urol 173: 1098-1101
20. Lane BR and Gill IS (2007) 5-Year outcomes of laparoscopic partial nephrectomy. J Urol 177: 70-74
21. Gill IS et al. (2007) Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors. J Urol 178: 41-46
22. Sutherland SE et al. (2002) Does the size of the surgical margin in partial nephrectomy for renal cell cancer really matter? J Urol 167: 61-64
23. Link RE et al. (2005) Exploring the learning curve, pathological outcomes and perioperative morbidity of laparoscopic partial nephrectomy performed for renal mass. J Urol 173:1690-1694
24. Abukora F et al. (2005) Laparoscopic nephron sparing surgery: evolution in a decade. Eur Urol 47: 488-493
25. Novick AG et al. (1989) Conservative surgery for renal cell carcinoma: A single-center experience with 100 patients. J Urol 141: 835-839
26. Licht MR and Novick AC (1993) Nephron sparing surgery for renal cell carcinoma. J Urol 149: 1-7
27. Novick AC (1993) Renal-sparing surgery for renal cell carcinoma. Urol Clin North Am 20:277-282
28. Polascik TJ et al. (1995) Partial nephrectomy: Technique, complications and pathological findings. J Urol 154:1312-1318
29. Hafez KS et al. (1997) Patterns of tumor recurrence and guidelines for followup after nephron sparing surgery for sporadic renal cell carcinoma. J Urol 157: 2067-2070
30. Herr HW (1999) Partial nephrectomy for unilateral renal carcinoma and a normal contralateral kidney: 10-year followup. J Urol 161: 33-35
31. Vermooten V (1950) Indications for conservative surgery in certain renal tumors: A study based on the growth pattern of the cell carcinoma. J Urol 64: 200-208
32. Russo P (2000) Renal cell carcinoma: Presentation, staging, and surgical treatment. Semin Oncol 27: 160-76
33. Piper NY et al. (2001) Is a 1-cm margin necessary during nephron-sparing surgery for renal cell carcinoma? Urology 58 849-062
34. Castilla EA et al. (2002) Prognostic importance of resection margin width after nephron-sparing surgery for renal cell carcinoma. Urology 60: 993-997
35. Li QL et al. (2003) Optimal margin in nephron-sparing surgery for renal cell carcinoma 4cm or less. Eur Urol 44:448-451
36. Timsit MO et al. (2006) Prospective study of safety margins in partial nephrectomy: Intraoperative assessment and contribution of frozen section analysis. Urology 67: 923-926
37. Berdjis N et al. (2006) Impact of resection margin status after nephron-sparing surgely for renal cell carcinoma. BJU Int 97 1208-1210
38. Lerner SE et al. (1996) Disease outcome in patients with low stage renal cell carcinoma treated with nephron sparing or radical surgery. J Urol 155: 1868-1873
39. Kwon EO et al. (2007) Impact of positive surgical margins in patients undergoing partial nephrectomy for renal cortical tumours. BJU Int 99: 286-289
40. Breda A et al. (2007) Positive margins in laparoscopic partial nephrectomy in 855 cases: A multi-institutional survey from the United States and Europe. J Urol 178: 47-50
41. Venkatesh R et al. (2006) Laparoscopic partial nephrectomy for renal masses: Effect of tumor location. Urology 67:1169-1174
42. Frank I et al. (2006) Laparoscopic partial naphrectomy for centrally located renal tumors. J Urol 175: 849-852
43. Permpongkosol S et al. (2096) Positive surgical parenchymal margin after laparoscopic partial nephrectomy for renal cell carcinoma: oncological outcomes. J Urol 178:2401-2404
44. Stein M et al. (1992) The value of postoperative irradiation in renal cell cancer. Radiother Oncol 24: 41-44
45. Gez E et al. (2002) Postoperative irradiation in localized renal cell carcinoma: The Rambam Medical Center experience. Tum0ri 88 500-502
46. Kjaer M et al. (1987) Postoperative radiotherapy in stage II and III renal adenocarcinoma. A randomized trial by the Copenhagen Renal Cancer Study Group. Int J Radiat Oncol Biol Phys 13:665-672
47. Itano NB et al. (2000) Outcome of isolated renal cell carcinoma fossa recurrence after nephrectomy. J Urol 164:322-325
48. Schrodter S et al. (2002) Outcome of surgical treatment of isolated local recurrence after radical nephrectomy for renal cell carcinoma. J Urol 187: 1630-1633
49. Gogus C et al. (2003) Isolated local recurrence of renal cell carcinoma after radical nephrectomy: Experience with 10 cases. Urology 61: 926-929
50. Bruno JJ Jr et al. (2006) Renal cell carcinoma local recurrences: impact of surgical treatment and concomitant metastasis on survival. BJU Int 97: 933-938
51. Tanguay S et al. (1996) Therapy of locally recurrent renal cell carcinoma after nephrectomy. J Urol 155: 26-29
52. Frydenberg M et al. (1994) Preoperative external beam radiotherapy followed by cytoreductive surgery and intraoperative radiotherapy for locally advanced primary or recurrent renal malignancies. J Urol 152: 15-21
53. Chawla SN et al. (2006) The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature. J Urol 175: 425-431
54. Carini M et al. (2006) Simple enucleation for the treatment of PT1a renal cell carcinoma: Our 20-year experience. Eur Urol 50 1263-1271
55. Carini M et al. (2006) Simple enucleation for the treatment of renal cell carcinoma between 4 and 7 cm in greatest dimension: progression and long-term survival. J Urol 175:2022-2026
56. Kubinski DJ et al. (2004) Utility of frozen section analysis of resection margins during partial nephrectomy. Urology 64: 31-34
57. Duvdevani M et al. (2005) Is frozen section analysis in nephron sparing surgery necessary? A clinicopathological study of 301 cases. J Urol 173: 385-387
58. Truong LD et al. (2005) Intraoperative pathology consultation for kidney and urinary bladder specimens. Arch Pathol Lab Med 129 1585-1601
59. McHale T et al. (2002) Potential pitfalls in the frozen section evaluation of parenchymal margins in nephron-sparing surgery. Am J Clin Pathol 118: 903-910
60. Polascik TJ et al. (1995) Intraoperative sonography for the evaluation and management of renal tumors: Experience with 100 patients. J Urol 154:1676-1680
61. Gill IS et al. (2002) Laparoscopic partial nephrectomy for renal tumor: Duplicating open surgical techniques. J Urol 167: 469-467
62. Weld KJ et al. (2006) Evolution of surgical technique and patient outcomes for laparoscopic partial nephrectomy. Urology 67: 502-507
63. Nguyen TT et al. (2005) Technique for ensuring negative surgical margins during laparoscopic partial nephrectomy. J Endourol 19 410-415
64. Gallucci M et al. (2007) Superselective embolization as first step of laparoscopic partial nephrectomy. Urology 69: 642-646
65. Sundaram CP et al. (2003) Hemostatic laparoscopic partial nephrectomy assisted by a water-cooled, high-density, monopolar device without renal vascular control. Urology 61: 906-909
66. Thompson RH et al. (2005) Complications of contemporary open nephron sparing surgery: A single institution experience. J Urol 174:855-858
67. Lee CT et al. (2000) Surgical management of renal tumors 4cm or less in a contemporary cohort. J Urol 163:730-736