Is processing speed predictive of functional outcome in psychosis?

Social Psychiatry and Psychiatric Epidemiology

Volumn 43, Issue 6, 2008, Pages 437-444

  Jabben, Nienke ^a   van Os, Jim ^a,b   Burns, Tom ^c   Creed, Francis ^d   Tattan, Theresa ^e   Green, John ^f   Tyrer, Peter ^g   Murray, Robin ^b   Krabbendam, Lydia ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^e West of England Forensic Mental Health Service   (United Kingdom)

^f CENTRAL AND NORTH WEST LONDON NHS FOUNDATION TRUST   (United Kingdom)

^g IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Functional outcome; Processing speed; Psychosis; Symptoms

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CASE MANAGEMENT; CHRONIC DISEASE; CLINICAL TRIAL; COGNITION; COGNITIVE DEFECT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; FOLLOW UP; FUNCTIONAL ASSESSMENT; HEALTH CARE NEED; HUMAN; INFORMATION PROCESSING; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; NEUROPSYCHOLOGICAL TEST; OUTCOMES RESEARCH; PREDICTION; PROGNOSIS; PSYCHOSIS; RANDOMIZED CONTROLLED TRIAL; REGRESSION ANALYSIS; SYMPTOMATOLOGY; UNITED KINGDOM;

ADOLESCENT; ADULT; AGED; COGNITION; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; GREAT BRITAIN; HOSPITALIZATION; HUMANS; LONGITUDINAL STUDIES; MALE; MENTAL PROCESSES; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; OUTCOME ASSESSMENT (HEALTH CARE); PREDICTIVE VALUE OF TESTS; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; QUALITY OF LIFE; SEVERITY OF ILLNESS INDEX; SOCIAL ADJUSTMENT; TIME FACTORS;

EID: 44949222679     PISSN: 09337954     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00127-008-0328-y     Document Type: Article

References (49)

1. Addington J, McCleary L, Munroe-Blum H (1998), Relationship between cognitive and social dysfunction in schizophrenia. Schizophr Res 34(1-2):59-66
2. Addington J, Saeedi H, Addington D (2005) The course of cognitive functioning in first episode psychosis: Changes over time and impact on outcome. Schizophr Res 78(1):35-43
3. Breier A et al. (1992) Course of illness and predictors of outcome in chronic schizophrenia: Implications for pathophysiology. Br J Psychiatry 161(Suppl 18):38-43
4. Brekke JS, Kohrt B, Green MF (2001) Neuropsychological functioning as a moderator of the relationship between psychosocial functioning and the subjective experience of self and life in schizophrenia. Schizophr Bull 27(4):697-708
5. Bryson G, Bell MD (2003) Initial and final work performance in schizohrenia: Cognitive and symptom predictors. J Nerv Ment Dis 191(2):87-92
6. Burns T et al. (1999) Intensive versus standard case management for severe psychotic illness: A randomised trial. UK 700 Group. Lancet 353(9171):2185-2189
7. Carlsson R et al. (2006) Neuropsychological functions predict 1- and 3-year outcome in first-episode psychosis. Acta Psychiatr Scand 113(2):102-111
8. Dickinson D et al. (2004) General and specific cognitive deficits in schizophrenia. Biol Psychiatry 55:826-833
9. Dickinson D, Coursey RD (2002) Independence and overlap among neurocognitive correlates of community functioning in schizophrenia. Schizophr Res 56(1-2):161-170
10. Fujii DE, Wylie AM (2002) Neurocognition and community outcome in schizophrenia: Long-term predictive validity. Schizophr Res 59:219-223
11. Gilvarry CM et al. (2001) Neuropsychological performance of psychotic patients in community care: Results from the UK700 study. Acta Psychiatr Scand Suppl 408:81-91
12. Gold JM et al. (2002) Cognitive correlates of job tenure among patients with severe mental illness. Am J Psychiatry 159(8):1395-1402
13. Green MF (1996) What are the functional consequences of neurocognitive deficits in schizophrenia? Am J Psychiatry 153(3):321-330
14. Green MF et al. (2000) Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the "Right Stuff"? Schizophr Bull 26(1):119-136
15. Green MF, Kern RS, Heaton RK (2004) Longitudinal studies of cognition and functional outcome in schizophrenia: Implications for MATRICS. Schizophr Res 72(1):41-51
16. Hassiotis A et al. (2001) Intellectual functioning and outcome of patients with severe psychotic illness randomised to intensive case management. Report from the UK700 trial. Br J Psychiatry 178:166-171
17. Holthausen EA et al. (2007) Predictive value of cognition for different domains of outcome in recent-onset schizophrenia. Psychiatry Res 149(1-3):71-80
18. Jablensky A, Schwartz R, Tomov T (1980) WHO collaborative study of impairments and disabilities associated with schizophrenic disorders: A preliminary communication. Objective and methods. Acta Psychiatr Scand Suppl 285(62):152-163
19. Jacobsson L et al. (1978) The comprehesive psychopathological rating scale-CPRS-in patients with schizophrenic syndromes. Inter-rater reliability and in relation to Martens' S-scale. Acta Psychiatr Scand Suppl 271:39-44
20. Lehman AF, Ward NC, Linn LS (1982) Chronic mental patients: The quality of life issue. Am J Psychiatry 139(10):1271-1276
21. Lezak M (1995) Neuropsychological assessment, 3rd edn. Oxford University Press, New York
22. Lieberman JA et al. (1996) Factors influencing treatment response and outcome of first-episode schizophrenia: Implications for understanding the patholophysiology of schizophrenia. J Clin Psychiatry 57(Suppl 9):5-9
23. Lysaker PH et al. (2005) Relationship of impaired processing speed and flexibility of abstract thought to improvements in work performance over time in schizophrenia. Schizophr Res 75(2-3):211-218
24. Malla AK et al. (2002) Symptoms, cognition, treatment adherence and functional outcome in first-episode psychosis. Psychol Med 32(6):1109-1119
25. Malla A, Payne J (2005) First-episode psychosis: Psychopathology, quality of life, and functional outcome. Schizophr Bull 31(3):650-671
26. Mc Guffin P, Farmer A, Harvey I (1991) A polydiagnostic application of operational criteria in studies of psychotic illness: Development and reliability of the OPCRIT system. Arch Gen Psychiatry 48:764-770
27. McGurk SR, Meltzer HY (2000) The role of cognition in vocational functioning in schizophrenia. Schizophr Res 45(3):175-184
28. Metcalfe C et al. (2005) Intensive case management for severe psychotic illness: Is there a general benefit for patients with complex needs? A secondary analysis of the UK700 trial data. Soc Psychiatry Psychiatr Epidemiol 40(9):718-724
29. Milev P et al. (2005) Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: A longitudinal first-episode study with 7-year follow-up. Am J Psychiatry 162(3):495-506
30. Nelson HE, Willison JR (1991) The revised national adult reading test manual, 2nd edn. Windsor, NFER-Nelson, UK
31. Norman RM et al. (1999) Symptoms and cognition as predictors of community functioning: A prospective analysis. Am J Psychiatry 156(3):400-405
32. Norman RMG et al. (2005) Social support and three-year symptom and admission outcomes for first-episode psychosis. Schizophr Res 80:227-234
33. Oliver JP et al. (1997) Measuring the quality of life of severely mentally ill people using the Lancashire quality of life profile. Soc Psychiatry Psychiatr Epidemiol 32(2):76-83
34. van Os J et al. (1999) To what extent does symptomatic improvement result in better outcome in psychotic illness? UK700 Group. Psychol Med 29(5):1183-1195
35. van Os J, Wright P, Murray RM (1997) Risk factors for emergence and persistence of psychosis. In: Weller M, Van Kammen D (Eds) Progress in clinical psychiatry. W. B. Saunders Company LTD, London, pp 152-206
36. Phelan M et al. (1995) The Camberwell assessment of need: The validity and reliability of an instrument to assess the needs of people with severe mental illness. Br J Psychiatry 167(5):589-595
37. Prouteau A et al. (2005) Cognitive predictors of psychosocial functioning outcome in schizophrenia: A follow-up study of subjects participating in a rehabilitation program. Schizophr Res 77(2-3):343-353
38. Reitan RM (1958) Validity of the trail making test as an indicator of organic brain dysfunction. Percept Mot Skills 8:271-276
39. Robinson DG et al. (2004) Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder. Am J Psychiatry 161(3):473-479
40. Rosenman S et al. (2003) Dimensional vs. categorical diagnosis in psychosis. Acta Psychiatr Scand 107:378-384
41. Smith TE et al. (1999) The relative influences of symptoms, insight, and neurocognition on social adjustment in schizophrenia and schizoaffective disorder. J Nerv Ment Dis 187(2):102-108
42. Sota TL, Heinrichs RW (2004) Demographic, clinical, and neurocognitive predictors of quality of life in schizophrenia patients receiving conventional neuroleptics. Compr Psychiatry 45(5):415-421
43. Spitzer RL, Endicott J, Robins E (1978) Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry 35(6):773-782
44. Stirling J et al. (2003) Neurocognitive function and outcome in first-episode schizophrenia: A 10-year follow-up of an epidemiological cohort. Schizophr Res 65(2-3):75-86
45. Tyrer P et al. (1999) Intensive case management for psychotic patients with borderline intelligence. UK 700 Group. Lancet 354(9183):999-1000
46. UK700Group (1999) Predictors of quality of life in people with severe mental illness. Study methodology with baseline analysis in the UK700 trial. Br J Psychiatry 175:426-432
47. UK700Group (1999) Comparison of intensive and standard case management for patients with psychosis. Rationale of the trial. UK700 Group. Br J Psychiatry 174:74-78
48. Verdoux H et al. (2002) Social and clinical consequences of cognitive deficits in early psychosis: A two-year follow-up study of first-admitted patients. Schizophr Res 56(1-2):149-159
49. WHO (1992) WHO coordinated multi-center study on the course and outcome of schizophrenia. WHO, Geneva