Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation

International Journal of Cancer

Volumn 123, Issue 2, 2008, Pages 484-489

  Van Der Gun, Bernardina T F ^a   Wasserkort, Reinhold ^b   Monami, Amélie ^c   Jeltsch, Albert ^d   Raskó, Tamás ^e   Ślaska Kiss, Krystyna ^e   Cortese, Rene ^b   Rots, Marianne G ^a   De Leij, Lou F M H ^a   Ruiters, Marcel H J ^a   Kiss, Antal ^e   Weinhold, Elmar ^c   McLaughlin, Pamela M J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b EPIGENOMICS AG   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d JACOBS UNIVERSITY BREMEN   (Germany)

^e INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

17 1A; CD326; DNA methylation; EGP 2 promoter; Gene silencing; M.SssI; siRNA; TROP1

Indexed keywords

BISULFITE; DNA; DNA METHYLTRANSFERASE; EPITHELIAL CELL ADHESION MOLECULE; MESSENGER RNA; SMALL INTERFERING RNA; ANTINEOPLASTIC AGENT; AZACITIDINE; CELL ADHESION MOLECULE; DNA MODIFICATION METHYLASE SSSI; SITE SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE SPECIFIC); TACSTD1 PROTEIN, HUMAN; TUMOR ANTIGEN;

ARTICLE; CARCINOGENESIS; CARCINOMA; CARCINOMA CELL; CELL DIVISION; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; EMBRYO; EPITHELIAL CELL ADHESION MOLECULE GENE; EPITHELIUM; FETUS; GENE; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; NONHUMAN; OVARY CARCINOMA; PRIORITY JOURNAL; TRANSCRIPTION INITIATION; UPREGULATION; CELL NUCLEUS; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; OVARY TUMOR; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; TUMOR CELL LINE;

ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; AZACITIDINE; CARCINOMA; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL NUCLEUS; DNA METHYLATION; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; OVARIAN NEOPLASMS; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SITE-SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE-SPECIFIC); TIME FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 44949161045     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23476     Document Type: Article

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