Replication in a superficial epithelial cell niche explains the lack of pathogenicity of primate foamy virus infections

Journal of Virology

Volumn 82, Issue 12, 2008, Pages 5981-5985

  Murray, Shannon M ^a,b,d   Picker, Louis J ^c   Axthelm, Michael K ^c   Hudkins, Kelly ^b   Alpers, Charles E ^b   Linial, Maxine L ^a,b  

^a USA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL TYPE; CONTROLLED STUDY; EPITHELIUM CELL; IN SITU HYBRIDIZATION; MOUTH MUCOSA; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PRIMATE; PRIORITY JOURNAL; RHESUS MONKEY; SALIVA; SIMIAN VIRUS; SPUMA VIRUS; VIRUS INFECTION; VIRUS REPLICATION; VIRUS SHEDDING; VIRUS TRANSMISSION;

ANIMALS; DNA, VIRAL; EPITHELIAL CELLS; IN SITU HYBRIDIZATION; MACACA MULATTA; MONKEY DISEASES; RETROVIRIDAE INFECTIONS; RNA, VIRAL; SPUMAVIRUS; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN SPUMARETROVIRUS; MACACA MULATTA; PRIMATES; RABBIT FIBROMA VIRUS; SIMIAE;

EID: 44949158024     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00367-08     Document Type: Article

References (26)

1. AVMA Panel on Euthanasia. 2001. 2000 Report of the AVMA Panel on Euthanasia. J. Am. Vet. Med. Assoc. 218:669-696.
2. Bieniasz, P. D., R. A. Weiss, and M. O. McClure. 1995. Cell cycle dependence of foamy retrovirus infection. J. Virol. 69:7295-7299.
3. Boneva, R. S., W. M. Switzer, T. J. Spira, V. B. Bhullar, V. Shanmugam, M. E. Cong, L. Lam, W. Heneine, T. M. Folks, and L. E. Chapman. 2007. Clinical and virological characterization of persistent human infection with simian foamy viruses. AIDS Res. Hum. Retrovir. 23:1330-1337.
4. Boyer, P. L., C. R. Stenbak, D. Hoberman, M. L. Linial, and S. H. Hughes. 2007. In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT. Virology 367:253-264.
5. Brooks, J. I., H. W. Merks, J. Fournier, R. S. Boneva, and P. A. Sandstrom. 2007. Characterization of blood-borne transmission of simian foamy virus. Transfusion 47:162-170.
6. Dawes, C. 2003. Estimates, from salivary analyses, of the turnover time of the oral mucosal epithelium in humans and the number of bacteria in an edentulous mouth. Arch. Oral Biol. 48:329-336.
7. Falcone, V., J. Leupold, J. Clotten, E. Urbanyi, O. Herchenröder, W. Spatz, B. Volk, N. Bölm, A. Toniolo, D. Neumann-Haefelin, and M. Schweizer. 1999. Sites of simian foamy virus persistence in naturally infected African green monkeys: latent provirus is ubiquitous, whereas viral replication is restricted to the oral mucosa. Virology 257:7-14.
8. Heneine, W., W. M. Switzer, P. Sandstrom, J. Brown, S. Vedapuri, C. A. Schable, A. S. Khan, N. W. Lerche, M. Schweizer, D. Neumann-Haefelin, L. E. Chapman, and T. M. Folks. 1998. Identification of a human population infected with simian foamy viruses. Nat. Med. 4:403-407.
9. Herchenroder, O., R. Turek, D. Neumann-Haefelin, A. Rethwilm, and J. Schneider. 1995. Infectious proviral clones of chimpanzee foamy virus (SFVcpz) generated by long PCR reveal close functional relatedness to human foamy virus. Virology 214:685-689.
10. Johnson, A. S., N. Maronian, and J. Vieira. 2005. Activation of Kaposi's sarcoma-associated herpesvirus lytic gene expression during epithelial differentiation. J. Virol. 79:13769-13777.
11. Jones-Engel, L., K. A. Steinkraus, S. M. Murray, G. A. Engel, R. Grant, N. Aggimarangsee, B. P. Y.-H. Lee, C. May, M. A. Schillaci, C. Somgird, T. Sutthipat, L. Vojtech, J.-Y. Zhao, and M. L. Linial. 2007. Sensitive assays for simian foamy viruses reveal a high prevalence of infection in commensal, free-ranging, Asian monkeys. J. Virol. 81:7330-7337.
12. Karlin, S., E. S. Mocarski, and G. A. Schachtel. 1994. Molecular evolution of herpesviruses: genomic and protein sequence comparisons. J. Virol. 68: 1886-1902.
13. Kirchoff, V., S. Wong, J. S. St, and G. S. Pari. 2002. Generation of a life-expanded rhesus monkey fibroblast cell line for the growth of rhesus rhadinovirus (RRV). Arch. Virol. 147:321-333.
14. Linial, M. L. 2007. Foamy viruses, p. 2245-2263. In D. M. Knipe and P. M. Howley (ed.), Fields virology. Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia, PA.
15. Meiering, C. D., and M. L. Linial. 2002. Reactivation of a complex retrovirus is controlled by a molecular switch and is inhibited by a viral protein. Proc. Natl. Acad. Sci. USA 99:15130-15135.
16. Meiering, C. D., C. Rubio, C. May, and M. L. Linial. 2001. Cell-type-specific regulation of the two foamy virus promoters. J. Virol. 75:6547-6557.
17. Meyer, J., S. J. Squier, and S. J. Gerson. 1984. The structure and function of oral mucosa. Pergamon Press, Oxford, United Kingdom.
18. Murray, S. M., L. J. Picker, M. K. Axthelm, and M. L. Linial. 2006. Expanded tissue targets for foamy virus replication with simian immunodeficiency virus-induced immunosuppression. J. Virol. 80:663-670.
19. Nakahara, T., A. Nishimura, M. Tanaka, T. Ueno, A. Ishimoto, and H. Sakai. 2002. Modulation of the cell division cycle by human papillomavirus type 18 E4. J. Virol. 76:10914-10920.
20. Ong, C. K., S. Y. Chan, M. S. Campo, K. Fujinaga, P. Mavromara-Nazos, V. Labropoulou, H. Pfister, S. K. Tay, J. ter Meulen, and L. L. Villa. 1993. Evolution of human papillomavirus type 18: an ancient phylogenetic root in Africa and intratype diversity reflect coevolution with human ethnic groups. J. Virol. 67:6424-6431.
21. Scholzen, T., and J. Gerdes. 2000. The Ki-67 protein: from the known and the unknown. J. Cell. Physiol. 182:311-322.
22. Switzer, W. M., V. Bhullar, V. Shanmugam, M. E. Cong, B. Parekh, N. W. Lerche, J. L. Yee, J. J. Ely, R. Boneva, L. E. Chapman, T. M. Folks, and W. Heneine. 2004. Frequent simian foamy virus infection in persons occupationally exposed to nonhuman primates. J. Virol. 78:2780-2789.
23. Switzer, W. M., M. Salemi, V. Shanmugam, F. Gao, M. E. Cong, C. Kuiken, V. Bhullar, B. E. Beer, D. Vallet, A. Gautier-Hion, Z. Tooze, F. Villinger, E. C. Holmes, and W. Heneine. 2005. Ancient co-speciation of simian foamy viruses and primates. Nature 434:376-380.
24. Trobridge, G., and D. W. Russell. 2004. Cell cycle requirements for transduction by foamy virus vectors compared to those of oncovirus and lentivirus vectors. J. Virol. 78:2327-2335.
25. Tugizov, S., R. Herrera, P. Veluppillai, J. Greenspan, D. Greenspan, and J. M. Palefsky. 2007. Epstein-Barr virus (EBV)-infected monocytes facilitate dissemination of EBV within the oral mucosal epithelium. J. Virol. 81:5484-5496.
26. Wolfe, N. D., W. M. Switzer, J. K. Carr, V. B. Bhullar, V. Shanmugam, U. Tamoufe, A. T. Prosser, J. N. Torimiro, A. Wright, E. Mpoudi-Ngole, F. E. McCutchan, D. L. Birx, T. M. Folks, D. S. Burke, and W. Heneine. 2004. Naturally acquired simian retrovirus infections in central African hunters. Lancet 363:932-937.