Microthermal techniques for mixing, concentration, and harvesting of DNA and other microdroplet suspensions

Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Volumn 1, Issue , 2005, Pages 131-134

  Basu, Amar S ^a   Gianchandani, Yogesh B ^a  

^a University of Michigan   (United States)

Author keywords

DNA precipitation; Microdroplet; Mixer; Preconcentration

Indexed keywords

CHEMICAL ANALYSIS; DNA; DROPS; MIXERS (MACHINERY); MIXING; PRECIPITATION (CHEMICAL);

CONTROLLED EVAPORATION; DNA PRECIPITATION; HIGH-SPEED MIXING; LOW CONCENTRATIONS; MICRO DROPLETS; POINT HEAT SOURCE; PRE-CONCENTRATION; SUSPENDED PARTICLES;

SUSPENSIONS (FLUIDS);

EID: 44949127684     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (9)

1. J. Passonneau, O. Lowry, Enzymatic Analysis, A Practical Guide. Totowa: Humana Press 1993.
2. M. He, C. Sun, D.T. Chiu, "Concentrating solutes and nanoparticles within individual aqueous microdroplets, " Anal. Chem., vol. 76, pg. 1222-1227, Mar. 2004.
3. M. Tanyeri, I.M. Kennedy, "Microdroplets for integrated high sensitivity biosensors, " Proc. SPIE, vol. 5275, pp 133-140, 2004.
4. M. Nakano, J. Komatsu, S. Matsuura, K. Takashima, S. Katsura, A. Mizuno, "Single molecule PCR using water-in-oil emulsion, " Jour. Biotech., vol. 102, pp. 117-124, Apr. 2003.
5. A. Ashkin, "Application of radiation pressure, " Science, vol. 210, pp. 1081-1087, Dec. 1980.
6. S. Katsura, A. Yamaguchi, N. Harada, K. Hirano, A. Mizuno, "Micro-reactors based on waterin- oil emulsion, " Proc. IEEE IAS Annual Meeting, vol. 2, pp. 1124-1129, Oct. 1999.
7. A.S. Basu, Y.B. Gianchandani, "Trapping and manipulation of particles and droplets using micro-toroidal convection currents, " Proc. Intl. Conf. on Solid State Sensors, Actuators, and Microsystems, vol. 13, pp. 85-88, June 2005.
8. R.D. Deegan, O. Bakajin, T.F. Dupont, G. Huber, S.R. Nagel, T.A. Witten, "Capillary flow as the cause of ring stains from dried liquid drops, " Nature, vol. 389, pp. 827 - 829, Oct. 1997.
9. M. Reading, D. Grandy, A. Hammiche, L. Bozec, H. Pollock, "Thermally assisted nanosampling and analysis using micro-IR spectroscopy and other analytical methods, " Vibrational Spectroscopy, vol. 29, pp 257-260, Jul. 2002.