The apolipoprotein A5 gene -1131T→C polymorphism affects vitamin E plasma concentrations in type 2 diabetic patients

Clinical Chemistry and Laboratory Medicine

Volumn 46, Issue 4, 2008, Pages 453-457

  Girona, Josefa ^a   Guardiola, Montse ^a   Cabré, Anna ^a   Manzanares, Josep M ^a   Heras, Mercedes ^a   Ribalta, Josep ^a   Masana, Lluís ^a,b  

^a INSTITUT D INVESTIGACIÓ SANITÀRIA PERE VIRGILI IISPV   (Spain)

^b FACULTAT DE MEDICINA I CIÈNCIES DE LA SALUT   (Spain)

Author keywords

APOA5; Oxidation; Triglycerides; Type 2 diabetes; Vitamin E

Indexed keywords

ALKADIENE; ALPHA TOCOPHEROL; APOLIPOPROTEIN A5; AUTOANTIBODY; DNA; HIGH DENSITY LIPOPROTEIN; LIPID; LIPID PEROXIDE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; COLORIMETRY; CONTROLLED STUDY; DNA EXTRACTION; DNA POLYMORPHISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC VARIABILITY; HEREDITY; HETEROZYGOTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIPID OXIDATION; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN LOCALIZATION;

ADULT; AGED; APOLIPOPROTEINS A; DIABETES MELLITUS, TYPE 2; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LIPIDS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; OXIDATIVE STRESS; POLYMORPHISM, GENETIC; TRIGLYCERIDES; VITAMIN E;

EID: 44949125723     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2008.110     Document Type: Article

References (32)

1. Ceriello A. Controlling oxidative stress as a novel molecular approach to protecting the vascular wall in diabetes. Curr Opin Lipidol 2006;17:510-8.
2. Jay D, Hitomi H, Griendling KK. Oxidative stress and diabetic cardiovascular complications. Free Radic Biol Med 2006;40:183-92.
3. Lonn E, Yusuf S, Hoogwerf B, Poque J, Yi Q, Zinman B, et al. Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: results of the HOPE study and MICRO-HOPE substudy. Diabetes Care 2002;25:1919-27.
4. Mezzetti A, Zuliani G, Romano F, Costantini F, Pierdomenico SD, Cuccurullo F, et al. Vitamin E and lipid peroxide plasma levels predict the risk of cardiovascular events in a group of healthy very old people. J Am Geriatr Soc 2001;49:533-7.
5. Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 2005;142:37-46.
6. Upston JM, Terentis AC, Morris K, Keaney JF Jr, Stocker R. Oxidized lipid accumulates in the presence of alpha-tocopherol in atherosclerosis. Biochem J 2002;363:753-60.
7. Fraley AE, Tsimikas S. Clinical applications of circulating oxidized low-density lipoprotein biomarkers in cardiovascular disease. Curr Opin Lipidol 2006;17:502-9.
8. Girona J, Vallve JC, Ribalta J, Heras M, Olive S, Masana L. 2,4-Decadienal downregulates TNF-alpha gene expression in THP-1 human macrophages. Atherosclerosis 2001;158:95-101.
9. Girona J, La Ville AE, Heras M, Olive S, Masana L. Oxidized lipoproteins including HDL and their lipid peroxidation products inhibit TNF-alpha secretion by THP-1 human macrophages. Free Radic Biol Med 1997;23:658-67.
10. Hacquebard M, Carpentier YA. Vitamin E: absorption, plasma transport and cell uptake. Curr Opin Clin Nutr Metab Care 2005;8:133-8.
11. Traber MG, Olivecrona T, Kayden HJ. Bovine milk lipoprotein lipase transfers tocopherol to human fibroblasts during triglyceride hydrolysis in vitro. J Clin Invest 1985;75:1729-34.
12. Arita M, Nomura K, Arai H, Inoue K. alpha-Tocopherol transfer protein stimulates the secretion of alpha-tocopherol from a cultured liver cell line through a brefeldin A-insensitive pathway. Proc Natl Acad Sci USA 1997;94:12437-41.
13. Hubacek JA. Apolipoprotein A5 and triglyceridemia. Focus on the effects of the common variants. Clin Chem Lab Med 2005;43:897-902.
14. Pennacchio LA, Olivier M, Hubacek JA, Cohen JC, Cox DR, Fruchart JC, et al. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science 2001;294:169-73.
15. Dallinga-Thie GM, van Tol A, Hattori H, van Vark-van der Zee LC, Jansen H, Sijbrands EJ. Plasma apolipoprotein A5 and triglycerides in type 2 diabetes. Diabetologia 2006;49:1505-11.
16. Chaaba R, Attia N, Hammami S, Smaoui M, Mahjoub S, Hammami M, et al. Association of SNP3 polymorphism in the apolipoprotein A-V gene with plasma triglyceride level in Tunisian type 2 diabetes. Lipids Health Dis 2005;4:1.
17. Yan SK, Cheng XQ, Song YH, Xiao XH, Bi N, Chen BS. Apolipoprotein A5 gene polymorphism -1131T→C: association with plasma lipids and type 2 diabetes mellitus with coronary heart disease in Chinese. Clin Chem Lab Med 2005;43:607-12.
18. Fruchart-Najib J, Bauge E, Niculescu LS, Pham T, Thomas B, Rommens C, et al. Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5. Biochem Biophys Res Commun 2004;319:397-404.
19. Weinberg RB, Cook VR, Beckstead JA, Martin DD, Gallagher JW, Shelness GS, et al. Structure and interfacial properties of human apolipoprotein A-V. J Biol Chem 2003;278:34438-44.
20. Krentz AJ. Lipoprotein abnormalities and their consequences for patients with type 2 diabetes. Diabetes Obes Metab 2003;5:S19-27.
21. Peters AL, Schriger DL. The new diagnostic criteria for diabetes: the impact on management of diabetes and macrovascular risk factors. Am J Med 1998;105:15S-19S.
22. Schumaker VN, Puppione DL. Sequential flotation ultra-centrifugation. Methods Enzymol 1986;128:155-70.
23. Esterbauer H, Striegl G, Puhl H, Rotheneder M. Continuous monitoring of in vitro oxidation of human low density lipoprotein. Free Radic Res Commun 1989;6:67-75.
24. Catignani GL, Bieri JG. Simultaneous determination of retinol and alpha-tocopherol in serum or plasma by liquid chromatography. Clin Chem 1983;29:708-12.
25. Olmedilla B, Granado F, Southon S, Wright AJ, Blanco I, Gil-Martinez E, et al. Serum concentrations of carotenoids and vitamins A, E, and C in control subjects from five European countries. Br J Nutr 2001;85:227-38.
26. Ribalta J, Figuera L, Fernandez-Ballart J, Vilella E, Castro Cabezas M, Masana L, et al. Newly identified apolipoprotein AV gene predisposes to high plasma triglycerides in familial combined hyperlipidemia. Clin Chem 2002;48:1597-1600.
27. Masana L, Ribalta J, Salazar J, Fernandez-Ballart J, Joven J, Cabezas MC. The apolipoprotein AV gene and diurnal triglyceridaemia in normolipidaemic subjects. Clin Chem Lab Med 2003;41:517-21.
28. Guardiola M, Ferre R, Salazar J, Alonso-Villaverde C, Coll B, Parra S, et al. Protease inhibitor-associated dyslipidemia in HIV-infected patients is strongly influenced by the APOA5-1131T→C gene variation. Clin Chem 2006;52:1914-9.
29. Sundl I, Guardiola M, Khoschsorur G, Solà R, Vallvé JC, Godàs G, et al. Increased concentrations of circulating vitamin E in carriers of the apolipoprotein A5 gene -1131T>C variant and associations with plasma lipids and lipid peroxidation. J Lipid Res 2007;48:2506-13.
30. Jang Y, Young Kim J, Yoen Kim O, Eun Lee J, Cho H, Ordovas JM, et al. The -1131T→C polymorphism in the apolipoprotein A5 gene is associated with postprandial hypertriacylglycerolemia; elevated small, dense LDL concentrations; and oxidative stress in nonobese Korean men. Am J Clin Nutr 2004;80:832-40.
31. Azzi A, Gysin R, Kempna P, Munteanu A, Negis Y, Villacorta L, et al. Vitamin E mediates cell signaling and regulation of gene expression. Ann NY Acad Sci 2004;1031:86-95.
32. Ishihara M, Kujiraoka T, Iwasaki T, Nagano M, Takano M, Ishii J, et al. A sandwich enzyme-linked immunosorbent assay for human plasma apolipoprotein A-V concentration. J Lipid Res 2005;46:2015-22.