메뉴 건너뛰기




Volumn 72, Issue 8, 2008, Pages 1890-1906

RNAi-mediated gene silencing in fishes?

Author keywords

dsRNA; Embryos; Fishes; RNA interference; shRNA; siRNA

Indexed keywords

EUKARYOTA; INVERTEBRATA; PISCES;

EID: 44949123711     PISSN: 00221112     EISSN: 10958649     Source Type: Journal    
DOI: 10.1111/j.1095-8649.2008.01819.x     Document Type: Review
Times cited : (16)

References (74)
  • 2
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou, L., Holt, A. C., Medzhitov, R. Flavell, R. A 2001). Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413, 732 738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 3
    • 26944498261 scopus 로고    scopus 로고
    • Approaches for chemically synthesized siRNA and vector-mediated RNAi
    • Amarzguioui, M., Rossi, J. J. Kim, D 2005). Approaches for chemically synthesized siRNA and vector-mediated RNAi. FEBS Letters 579, 5974 5981.
    • (2005) FEBS Letters , vol.579 , pp. 5974-5981
    • Amarzguioui, M.1    Rossi, J.J.2    Kim, D.3
  • 4
    • 26944443861 scopus 로고    scopus 로고
    • Identification and characterization of small RNAs involved in RNA silencing
    • Aravin, A. Tuschl, T 2005). Identification and characterization of small RNAs involved in RNA silencing. FEBS Letters 579, 5830 5840.
    • (2005) FEBS Letters , vol.579 , pp. 5830-5840
    • Aravin, A.1    Tuschl, T.2
  • 6
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D. P 2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281 297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 8
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein, E., Caudy, A. A., Hammond, S. M. Hannon, G. J 2001). Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363 366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 11
    • 1342268939 scopus 로고    scopus 로고
    • Short interfering RNA (siRNA)-mediated RNA interference (RNAi) in human cells
    • Caplen, N. J. Mousses, S 2003). Short interfering RNA (siRNA)-mediated RNA interference (RNAi) in human cells. Annals of the New York Academy of Sciences 1002, 56 62.
    • (2003) Annals of the New York Academy of Sciences , vol.1002 , pp. 56-62
    • Caplen, N.J.1    Mousses, S.2
  • 12
    • 0034636715 scopus 로고    scopus 로고
    • DsRNA-mediated gene silencing in cultured Drosophila cells: A tissue culture model for the analysis of RNA interference
    • Caplen, N. J., Fleenor, J., Fire, A. Morgan, R. A 2000). dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference. Gene 252, 95 105.
    • (2000) Gene , vol.252 , pp. 95-105
    • Caplen, N.J.1    Fleenor, J.2    Fire, A.3    Morgan, R.A.4
  • 13
    • 26944461214 scopus 로고    scopus 로고
    • Organization and promoter analysis of the zebrafish (Danio rerio) interferon gene
    • Chen, J. Y., You, Y. K., Chen, J. C., Huang, T. C. Kuo, C. M 2005). Organization and promoter analysis of the zebrafish (Danio rerio) interferon gene. DNA Cell Biology 24, 641 650.
    • (2005) DNA Cell Biology , vol.24 , pp. 641-650
    • Chen, J.Y.1    You, Y.K.2    Chen, J.C.3    Huang, T.C.4    Kuo, C.M.5
  • 16
    • 0037146606 scopus 로고    scopus 로고
    • Breakthrough of the year. Small RNAs make big splash
    • Couzin, J 2002). Breakthrough of the year. Small RNAs make big splash. Science 298, 2296 2297.
    • (2002) Science , vol.298 , pp. 2296-2297
    • Couzin, J.1
  • 17
    • 33846149304 scopus 로고    scopus 로고
    • Conditional transgene and gene targeting methodologies in zebrafish
    • Deiters, A. Yoder, J. A 2006). Conditional transgene and gene targeting methodologies in zebrafish. Zebrafish 3, 415 429.
    • (2006) Zebrafish , vol.3 , pp. 415-429
    • Deiters, A.1    Yoder, J.A.2
  • 19
    • 1542298263 scopus 로고    scopus 로고
    • Short interfering RNA-mediated gene targeting in the zebrafish
    • Dodd, A., Chambers, S. P. Love, D. R 2004). Short interfering RNA-mediated gene targeting in the zebrafish. FEBS Letters 561, 89 93.
    • (2004) FEBS Letters , vol.561 , pp. 89-93
    • Dodd, A.1    Chambers, S.P.2    Love, D.R.3
  • 20
    • 33745762405 scopus 로고    scopus 로고
    • Sequence analysis and functional study of thymidylate synthase from zebrafish, Danio rerio
    • Du, C., Niu, R., Chu, E., Zhang, P. Lin, X 2006). Sequence analysis and functional study of thymidylate synthase from zebrafish, Danio rerio. Journal of Biochemistry (Tokyo) 139, 913 920.
    • (2006) Journal of Biochemistry (Tokyo) , vol.139 , pp. 913-920
    • Du, C.1    Niu, R.2    Chu, E.3    Zhang, P.4    Lin, X.5
  • 21
    • 0033779565 scopus 로고    scopus 로고
    • Targeting zebrafish
    • Editorial (
    • Editorial (2000). Targeting zebrafish. Nature Genetics 26, 129 130.
    • (2000) Nature Genetics , vol.26 , pp. 129-130
  • 23
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K. Tuschl, T 2001a). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494 498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 24
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir, S. M., Lendeckel, W. Tuschl, T 2001b). RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Development 15, 188 200.
    • (2001) Genes Development , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 25
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir, S. M., Martinez, J., Patkaniowska, A., Lendeckel, W. Tuschl, T 2001c). Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO Journal 20, 6877 6888.
    • (2001) EMBO Journal , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 26
    • 33646003869 scopus 로고    scopus 로고
    • Betanodavirus B2 is an RNA interference antagonist that facilitates intracellular viral RNA accumulation
    • Fenner, B. J., Thiagarajan, R., Chua, H. K. Kwang, J 2006a). Betanodavirus B2 is an RNA interference antagonist that facilitates intracellular viral RNA accumulation. Journal of Virology 80, 85 94.
    • (2006) Journal of Virology , vol.80 , pp. 85-94
    • Fenner, B.J.1    Thiagarajan, R.2    Chua, H.K.3    Kwang, J.4
  • 27
    • 33745782055 scopus 로고    scopus 로고
    • Sequestration and protection of double-stranded RNA by the betanodavirus b2 protein
    • Fenner, B. J., Goh, W. Kwang, J 2006b). Sequestration and protection of double-stranded RNA by the betanodavirus b2 protein. Journal of Virology 80, 6822 6833.
    • (2006) Journal of Virology , vol.80 , pp. 6822-6833
    • Fenner, B.J.1    Goh, W.2    Kwang, J.3
  • 28
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E. Mello, C. C 1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806 811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 32
    • 30844459730 scopus 로고    scopus 로고
    • Specific RNAi mediated gene knock-down in zebrafish cell lines
    • Gruber, J., Manninga, H., Tuschl, T., Osborn, M. Weber, K. (2005). Specific RNAi mediated gene knock-down in zebrafish cell lines. RNA Biology 2, 101 105.
    • (2005) RNA Biology , vol.2 , pp. 101-105
    • Gruber, J.1    Manninga, H.2    Tuschl, T.3    Osborn, M.4    Weber, K.5
  • 33
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in posttranscriptional gene silencing in plants
    • Hamilton, A. J. Baulcombe, D. C 1999). A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 286, 950 952.
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.J.1    Baulcombe, D.C.2
  • 34
    • 26944441255 scopus 로고    scopus 로고
    • Dicing and slicing: The core machinery of the RNA interference pathway
    • Hammond, S. M 2005). Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Letters 579, 5822 5829.
    • (2005) FEBS Letters , vol.579 , pp. 5822-5829
    • Hammond, S.M.1
  • 35
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond, S. M., Bernstein, E., Beach, D. Hannon, G. J 2000). An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404, 293 296.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 37
    • 0036827108 scopus 로고    scopus 로고
    • Zebrafish M2 muscarinic acetylcholine receptor: Cloning, pharmacological characterization, expression patterns and roles in embryonic bradycardia
    • Hsieh, D. J. Liao, C. F 2002). Zebrafish M2 muscarinic acetylcholine receptor: cloning, pharmacological characterization, expression patterns and roles in embryonic bradycardia. British Journal of Pharmacology 137, 782 792.
    • (2002) British Journal of Pharmacology , vol.137 , pp. 782-792
    • Hsieh, D.J.1    Liao, C.F.2
  • 38
    • 33748710614 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 influences Rohon-Beard neuron survival in zebrafish
    • Kanungo, J., Li, B. S., Zheng, Y. Pant, H. C 2006). Cyclin-dependent kinase 5 influences Rohon-Beard neuron survival in zebrafish. Journal of Neurochemistry 99, 251 259.
    • (2006) Journal of Neurochemistry , vol.99 , pp. 251-259
    • Kanungo, J.1    Li, B.S.2    Zheng, Y.3    Pant, H.C.4
  • 40
    • 0034650510 scopus 로고    scopus 로고
    • Double-stranded RNA injection produces null phenotypes in zebrafish
    • Li, Y. X., Farrell, M. J., Liu, R., Mohanty, N. Kirby, M. L 2000). Double-stranded RNA injection produces null phenotypes in zebrafish. Developmental Biology 217, 394 405.
    • (2000) Developmental Biology , vol.217 , pp. 394-405
    • Li, Y.X.1    Farrell, M.J.2    Liu, R.3    Mohanty, N.4    Kirby, M.L.5
  • 41
    • 13544275934 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-3 plays an important role in regulating pharyngeal skeleton and inner ear formation and differentiation
    • Li, Y., Xiang, J. Duan, C 2005). Insulin-like growth factor-binding protein-3 plays an important role in regulating pharyngeal skeleton and inner ear formation and differentiation. The Journal of Biological Chemistry 280, 3613 3620.
    • (2005) The Journal of Biological Chemistry , vol.280 , pp. 3613-3620
    • Li, Y.1    Xiang, J.2    Duan, C.3
  • 48
    • 13844254210 scopus 로고    scopus 로고
    • Time course study of in situ expression of antigens following DNA-vaccination against VHS in rainbow trout (Oncorhynchus mykiss Walbaum) fry
    • Lorenzen, E., Lorenzen, N., Einer-Jensen, K., Brudeseth, B. Evensen, O 2005). Time course study of in situ expression of antigens following DNA-vaccination against VHS in rainbow trout (Oncorhynchus mykiss Walbaum) fry. Fish and Shellfish Immunology 19, 27 41.
    • (2005) Fish and Shellfish Immunology , vol.19 , pp. 27-41
    • Lorenzen, E.1    Lorenzen, N.2    Einer-Jensen, K.3    Brudeseth, B.4    Evensen, O.5
  • 49
    • 2442679207 scopus 로고    scopus 로고
    • Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
    • Ma, J. B., Ye, K. Patel, D. J 2004). Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 429, 318 322.
    • (2004) Nature , vol.429 , pp. 318-322
    • Ma, J.B.1    Ye, K.2    Patel, D.J.3
  • 50
    • 15844371219 scopus 로고    scopus 로고
    • Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
    • Ma, J. B., Yuan, Y. R., Meister, G., Pei, Y., Tuschl, T. Patel, D. J 2005). Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature 434, 666 670.
    • (2005) Nature , vol.434 , pp. 666-670
    • Ma, J.B.1    Yuan, Y.R.2    Meister, G.3    Pei, Y.4    Tuschl, T.5    Patel, D.J.6
  • 55
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into Petunia results in reversible co-suppression of homologous genes in trans
    • Napoli, C., Lemieux, C. Jorgensen, R 1990). Introduction of a chimeric chalcone synthase gene into Petunia results in reversible co-suppression of homologous genes in trans. The Plant Cell 2, 279 289.
    • (1990) The Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 56
    • 0033780376 scopus 로고    scopus 로고
    • Effective targeted gene 'knockdown' in zebrafish
    • Nasevicius, A. Ekker, S. C 2000). Effective targeted gene 'knockdown' in zebrafish. Nature Genetics 26, 216 220.
    • (2000) Nature Genetics , vol.26 , pp. 216-220
    • Nasevicius, A.1    Ekker, S.C.2
  • 57
    • 0034254815 scopus 로고    scopus 로고
    • Too much interference: Injection of double-stranded RNA has nonspecific effects in the zebrafish embryo
    • Oates, A. C., Bruce, A. E. Ho, R. K 2000). Too much interference: injection of double-stranded RNA has nonspecific effects in the zebrafish embryo. Developmental Biology 224, 20 28.
    • (2000) Developmental Biology , vol.224 , pp. 20-28
    • Oates, A.C.1    Bruce, A.E.2    Ho, R.K.3
  • 58
    • 11244279683 scopus 로고    scopus 로고
    • Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity
    • Parker, J. S., Roe, S. M. Barford, D 2004). Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity. The EMBO Journal 23, 4727 4737.
    • (2004) The EMBO Journal , vol.23 , pp. 4727-4737
    • Parker, J.S.1    Roe, S.M.2    Barford, D.3
  • 59
    • 15844402005 scopus 로고    scopus 로고
    • Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
    • Parker, J. S., Roe, S. M. Barford, D 2005). Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex. Nature 434, 663 666.
    • (2005) Nature , vol.434 , pp. 663-666
    • Parker, J.S.1    Roe, S.M.2    Barford, D.3
  • 60
    • 0026441194 scopus 로고
    • Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
    • Romano, N. Macino, G 1992). Quelling: transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Molecular Microbiology 6, 3343 3353.
    • (1992) Molecular Microbiology , vol.6 , pp. 3343-3353
    • Romano, N.1    MacIno, G.2
  • 61
    • 2342626647 scopus 로고    scopus 로고
    • The RNA-induced silencing complex is a Mg2+-dependent endonuclease
    • Schwarz, D. S., Tomari, Y. Zamore, P. D 2004). The RNA-induced silencing complex is a Mg2+-dependent endonuclease. Current Biology 14, 787 791.
    • (2004) Current Biology , vol.14 , pp. 787-791
    • Schwarz, D.S.1    Tomari, Y.2    Zamore, P.D.3
  • 62
    • 33745676386 scopus 로고    scopus 로고
    • Antiviral activity of small interfering RNAs: Specificity testing using heterologous virus reveals interferon-related effects overlooked by conventional mismatch controls
    • Schyth, B. D., Lorenzen, N. Pedersen, F. S 2006). Antiviral activity of small interfering RNAs: specificity testing using heterologous virus reveals interferon-related effects overlooked by conventional mismatch controls. Virology 349, 134 141.
    • (2006) Virology , vol.349 , pp. 134-141
    • Schyth, B.D.1    Lorenzen, N.2    Pedersen, F.S.3
  • 63
    • 34250742425 scopus 로고    scopus 로고
    • A high throughput in vivo model for testing delivery and antiviral effects of siRNAs in vertebrates
    • Schyth, B. D., Lorenzen, N. Pedersen, F. S 2007). A high throughput in vivo model for testing delivery and antiviral effects of siRNAs in vertebrates. Molecular Therapy 15, 1366 1372.
    • (2007) Molecular Therapy , vol.15 , pp. 1366-1372
    • Schyth, B.D.1    Lorenzen, N.2    Pedersen, F.S.3
  • 64
    • 33646049347 scopus 로고    scopus 로고
    • Innate sensing of self and non-self RNAs by Toll-like receptors
    • Sioud, M. (2006). Innate sensing of self and non-self RNAs by Toll-like receptors. Trends in Molecular Medicine 12, 167 176.
    • (2006) Trends in Molecular Medicine , vol.12 , pp. 167-176
    • Sioud, M.1
  • 65
    • 0033766888 scopus 로고    scopus 로고
    • Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference
    • Svoboda, P., Stein, P., Hayashi, H. Schultz, R. M 2000). Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference. Development 127, 4147 4156.
    • (2000) Development , vol.127 , pp. 4147-4156
    • Svoboda, P.1    Stein, P.2    Hayashi, H.3    Schultz, R.M.4
  • 66
    • 0034683099 scopus 로고    scopus 로고
    • Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target
    • Ui-Tei, K., Zenno, S., Miyata, Y. Saigo, K 2000). Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target. FEBS Letters 479, 79 82.
    • (2000) FEBS Letters , vol.479 , pp. 79-82
    • Ui-Tei, K.1    Zenno, S.2    Miyata, Y.3    Saigo, K.4
  • 68
    • 0033789992 scopus 로고    scopus 로고
    • Specific interference with gene function by double-stranded RNA in early mouse development
    • Wianny, F. Zernicka-Goetz, M 2000). Specific interference with gene function by double-stranded RNA in early mouse development. Nature Cell Biology 2, 70 75.
    • (2000) Nature Cell Biology , vol.2 , pp. 70-75
    • Wianny, F.1    Zernicka-Goetz, M.2
  • 69
    • 34247324772 scopus 로고    scopus 로고
    • Cloning and analysis of antiviral activity of a barramundi (Lates calcarifer) Mx gene
    • Wu, Y. C. Chi, S. C 2007) Cloning and analysis of antiviral activity of a barramundi (Lates calcarifer) Mx gene. Fish and Shellfish Immunology 23, 97 108.
    • (2007) Fish and Shellfish Immunology , vol.23 , pp. 97-108
    • Wu, Y.C.1    Chi, S.C.2
  • 70
    • 20644438444 scopus 로고    scopus 로고
    • Inhibition of reporter gene and Iridovirus-tiger frog virus in fish cell by RNA interference
    • Xie, J., Lu, L., Deng, M., Weng, S., Zhu, J., Wu, Y., Gan, L., Chan, S. M. He, J 2005). Inhibition of reporter gene and Iridovirus-tiger frog virus in fish cell by RNA interference. Virology 338, 43 52.
    • (2005) Virology , vol.338 , pp. 43-52
    • Xie, J.1    Lu, L.2    Deng, M.3    Weng, S.4    Zhu, J.5    Wu, Y.6    Gan, L.7    Chan, S.M.8    He, J.9
  • 71
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore, P. D., Tuschl, T., Sharp, P. A. Bartel, D. P 2000). RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101, 25 33.
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 72
    • 0036845374 scopus 로고    scopus 로고
    • Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
    • Zhang, H., Kolb, F. A., Brondani, V., Billy, E. Filipowicz, W 2002). Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO Journal 21, 5875 5885.
    • (2002) EMBO Journal , vol.21 , pp. 5875-5885
    • Zhang, H.1    Kolb, F.A.2    Brondani, V.3    Billy, E.4    Filipowicz, W.5
  • 73
    • 3142613181 scopus 로고    scopus 로고
    • Single processing center models for human Dicer and bacterial RNase III
    • Zhang, H., Kolb, F. A., Jaskiewicz, L., Westhof, E. Filipowicz, W 2004). Single processing center models for human Dicer and bacterial RNase III. Cell 118, 57 68.
    • (2004) Cell , vol.118 , pp. 57-68
    • Zhang, H.1    Kolb, F.A.2    Jaskiewicz, L.3    Westhof, E.4    Filipowicz, W.5
  • 74
    • 0035164784 scopus 로고    scopus 로고
    • Double-stranded RNA injection produces nonspecific defects in zebrafish
    • Zhao, Z., Cao, Y., Li, M. Meng, A 2001). Double-stranded RNA injection produces nonspecific defects in zebrafish. Developmental Biology 229, 215 223.
    • (2001) Developmental Biology , vol.229 , pp. 215-223
    • Zhao, Z.1    Cao, Y.2    Li, M.3    Meng, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.