Toxicogenomics in drug safety assessment

Pharmacogenomics

Volumn 9, Issue 4, 2008, Pages 379-382

  Hewitt, Philip ^a   Walijew, Alexandra ^a  

^a Merck Serono GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; OLIGONUCLEOTIDE;

BIOINFORMATICS; CARCINOGENICITY; CONFERENCE PAPER; DISEASE MARKER; DNA MICROARRAY; DRUG METABOLISM; DRUG RESEARCH; DRUG SAFETY; ENVIRONMENTAL FACTOR; FOOD AND DRUG ADMINISTRATION; FOOD DRUG INTERACTION; GENE SILENCING; GENE TECHNOLOGY; GENETIC SCREENING; GENOTOXICITY; HEART VENTRICLE HYPERTROPHY; HUMAN; INFORMATION RETRIEVAL; INFORMATION SYSTEM; INTESTINE FLORA; LIFESTYLE; NONHUMAN; PHARMACOGENOMICS; PREDICTION; PROGNOSIS; QUALITY CONTROL; RISK ASSESSMENT; TOXICOGENETICS; TOXICOGENOMICS;

ANIMALS; COMPUTATIONAL BIOLOGY; DRUG TOXICITY; HUMANS; TECHNOLOGY, PHARMACEUTICAL; TOXICOGENETICS; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 44949123498     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/14622416.9.4.379     Document Type: Conference Paper

References (5)

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3. Russell WMS, Burch RL: The principles of humane experimental technique. Methuen, London, UK (1959).
4. Kruetzfeldt J, Rajewsky N, Braich R et al.: Silencing of microRNAs in vivo with 'antagomirs'. Nature 438(7068), 685-689 (2005).
5. Thum T, Galuppo P, Wolf C et al.: MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation 116(3), 258-267 (2007).