Triad of severe abdominal pain, inappropriate antidiuretic hormone secretion, and disseminated varicella-zoster virus infection preceding cutaneous manifestations after hematopoietic stem cell transplantation: Utility of pcr for early recognition and therapy

Pediatric Infectious Disease Journal

Volumn 27, Issue 3, 2008, Pages 265-268

  Rau, Rachel ^a   Fitzhugh, Courtney D ^a   Baird, Kristin ^a   Cortez, Karroll J ^a   Li, Li ^b   Fischer, Steven H ^b   Cowen, Edward W ^a   Balow, James E ^c   Walsh, Thomas J ^a   Cohen, Jeffrey I ^d   Wayne, Alan S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Clinical Center

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Abdominal pain; Hematopoietic stem cell transplantation; Immunocompromised host; Syndrome of inappropriate diuretic hormone; Varicella zoster virus infection

Indexed keywords

ACICLOVIR; ANTIBIOTIC AGENT; ANTIVIRUS AGENT; CASPOFUNGIN; COTRIMOXAZOLE; DEMECLOCYCLINE; DEXAMETHASONE; ESTROGEN; FAMCICLOVIR; FOSCARNET; IMMUNOGLOBULIN; MEROPENEM; METRONIDAZOLE; MORPHINE; PREDNISONE; SODIUM; VALACICLOVIR; VANCOMYCIN; VIRUS DNA; VASOPRESSIN DERIVATIVE;

ABDOMINAL PAIN; ACUTE GRAFT VERSUS HOST DISEASE; ACUTE LYMPHOCYTIC LEUKEMIA; ADULT; ARTICLE; CASE REPORT; DISEASE COURSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HERPES ZOSTER; HUMAN; INAPPROPRIATE VASOPRESSIN SECRETION; INFECTION; LEUKOCYTE COUNT; NEUTROPENIA; PNEUMATOSIS INTESTINALIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SODIUM BLOOD LEVEL; TREATMENT OUTCOME; VARICELLA ZOSTER VIRUS; VIRUS DETECTION; VIRUS INFECTION; VIRUS LOAD; BLOOD; ISOLATION AND PURIFICATION; METHODOLOGY; PANCREATITIS;

ABDOMINAL PAIN; ACYCLOVIR; ADULT; ANTIVIRAL AGENTS; DNA, VIRAL; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HERPES ZOSTER; HERPESVIRUS 3, HUMAN; HUMANS; PANCREATITIS; PNEUMATOSIS CYSTOIDES INTESTINALIS; POLYMERASE CHAIN REACTION; VASOPRESSINS;

EID: 44949115290     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e31815cb239     Document Type: Article

References (17)

1. Rogers SY, Irving W, Harris A, Russell NH. Visceral varicella zoster infection after bone marrow transplantation without skin involvement and the use of PCR for diagnosis. Bone Marrow Transplant. 1995;15: 805-807.
2. David DS, Tegtmeier BR, O'Donnell MR, Paz IB, McCarty TM. Visceral varicella-zoster after bone marrow transplantation: report of a case series and review of the literature. Am J Gastroenterol. 1998;93: 810-813.
3. Koc Y, Miller KB, Schenkein DP, et al. Varicella zoster virus infections following allogeneic bone marrow transplantation: frequency, risk factors, and clinical outcome. Biol Blood Marrow Transplant. 2000;6:44-49.
4. Leung TF, Chik KW, Li CK, et al. Incidence, risk factors and outcome of varicella-zoster virus infection in children after haematopoietic stem cell transplantation. Bone Marrow Transplant. 2000;25:167-172.
5. Berman JN, Wang M, Berry W, Neuberg DS, Guinan EC. Herpes zoster infection in the post-hematopoietic stem cell transplant pediatric population may be preceded by transaminitis: an institutional experience. Bone Marrow Transplant. 2006;37:73-80.
6. Morgan ER, Smalley LA. Varicella in immunocompromised children. Incidence of abdominal pain and organ involvement. Am J Dis Child. 1983;137:883-885.
7. Pui JC, Furth EE, Minda J, Montone KT. Demonstration of varicella-zoster virus infection in the muscularis propria and myenteric plexi of the colon in an HIV-positive patient with herpes zoster and small bowel pseudo-obstruction (Ogilvie's syndrome). Am J Gastroenterol. 2001;96: 1627-1630.
8. Ingraham IE Jr, Estes NA, Bern MM, DeGirolami PC. Disseminated varicella-zoster virus infection with the syndrome of inappropriate antidiuretic hormone. Arch Intern Med. 1983;143:1270-1271.
9. McIlwaine LM, Fitzsimons EJ, Soutar RL. Inappropriate antidiuretic hormone secretion, abdominal pain and disseminated varicella-zoster virus infection: an unusual and fatal triad in a patient 13 months post Rituximab and autologous stem cell transplantation. Clin Lab Haematol. 2001;23:253-254.0
10. Au WY, Ma SY, Cheng VC, Ooi CG, Lie AK. Disseminated zoster, hyponatraemia, severe abdominal pain and leukaemia relapse: recognition of a new clinical quartet after bone marrow transplantation. Br J Dermatol. 2003;149:862-865.1
11. Szabo F, Horvath N, Seimon S, Hughes T. Inappropriate antidiuretic hormone secretion, abdominal pain and disseminated varicella-zoster virus infection: an unusual triad in a patient 6 months post miniallogeneic peripheral stem cell transplant for chronic myeloid leukemia. Bone Marrow Transplant. 2000;26:231-233.2
12. Drakos P, Weinberger M, Delukina M, Or R, Nagler A, Weinberger M. Inappropriate antidiuretic hormone secretion (SIADH) preceding skin manifestations of disseminated varicella zoster virus infection post-BMT. Bone Marrow Transplant. 1993;11:407-408.3
13. Vinzio S, Lioure B, Enescu I, Schlienger JL, Goichot B. Severe abdominal pain and inappropriate antidiuretic hormone secretion preceding varicella-zoster virus reactivation 10 months after autologous stem cell transplantation for acute myeloid leukaemia. Bone Marrow Transplant. 2005;35:525-527.4
14. Steer CB, Szer J, Sasadeusz J, Matthews JP, Beresford JA, Grigg A. Varicella-zoster infection after allogeneic bone marrow transplantation: incidence, risk factors and prevention with low-dose aciclovir and ganciclovir. Bone Marrow Transplant. 2000;25:657-664.5
15. de Jong MD, Weel JF, van Oers MH, Boom R, Wertheim van Dillen PM. Molecular diagnosis of visceral herpes zoster. Lancet. 2001;357: 2101-2102.6
16. Ishizaki Y, Tezuka J, Ohga S, et al. Quantification of circulating varicella zoster virus-DNA for the early diagnosis of visceral varicella. J Infect. 2003;47:133-138.7
17. Wilson A, Sharp M, Koropchak CM, Ting SF, Arvin AM. Subclinical varicella-zoster virus viremia, herpes zoster, and T lymphocyte immunity to varicella-zoster viral antigens after bone marrow transplantation. J Infect Dis. 1992;165:119-126.