Evidence for efficient phosphorylation of EGFR and rapid endocytosis of phosphorylated EGFR via the early/late endocytic pathway in a gefitinib-sensitive non-small cell lung cancer cell line

Molecular Cancer

Volumn 7, Issue , 2008, Pages

  Nishimura, Yukio ^a   Yoshioka, Kiyoko ^b   Bereczky, Biborka ^a   Itoh, Kazuyuki ^b  

^a KYUSHU UNIVERSITY   (Japan)

^b OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GEFITINIB; GENE PRODUCT; SORTING NEXIN 1 PROTEIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; QUINAZOLINE DERIVATIVE; SNX1 PROTEIN, HUMAN; VESICULAR TRANSPORT PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER RESISTANCE; CELL MIGRATION; CELL NUCLEUS; CELL STIMULATION; CONTROLLED STUDY; CYTOPLASM; DRUG SENSITIVITY; ENDOCYTOSIS; ENDOSOME; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTERNALIZATION; LUNG NON SMALL CELL CANCER; LYSOSOME; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; DRUG EFFECT; FLUORESCENCE MICROSCOPY; LUNG TUMOR; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

BIOLOGICAL TRANSPORT; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; ENDOCYTOSIS; ENDOSOMES; EPIDERMAL GROWTH FACTOR; HUMANS; LUNG NEOPLASMS; LYSOSOMES; MICROSCOPY, FLUORESCENCE; PHOSPHORYLATION; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; VESICULAR TRANSPORT PROTEINS;

EID: 44949107296     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-7-42     Document Type: Article

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