Intraspecies transmission of BASE induces clinical dullness and amyotrophic changes

PLoS Pathogens

Volumn 4, Issue 5, 2008, Pages

  Lombardi, Guerino ^a   Casalone, Cristina ^b   D'Angelo, Antonio ^c   Gelmetti, Daniela ^a   Torcoli, Gloria ^a   Barbieri, Ilaria ^a   Corona, Cristiano ^b   Fasoli, Elisa ^d   Farinazzo, Alessia ^d   Fiorini, Michele ^d   Gelati, Matteo ^d   Iulini, Barbara ^b   Tagliavini, Fabrizio ^e   Ferrari, Sergio ^d   Caramelli, Maria ^b   Monaco, Salvatore ^d   Capucci, Lorenzo ^a   Zanusso, Gianluigi ^d  

^a ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA LOMBARDIA E DELL EMILIA ROMAGNA   (Italy)

^b LIGURIA E VALLE D AOSTA   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d UNIVERSITY OF VERONA   (Italy)

^e DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN; AMYLOID; BIOLOGICAL MARKER; GLIAL FIBRILLARY ACIDIC PROTEIN;

AMYLOIDOSIS; ANIMAL TISSUE; ARTICLE; BOVINE AMYLOIDOTIC SPONGIFORM ENCEPHALOPATHY; BOVINE SPONGIFORM ENCEPHALOPATHY; CATTLE; DISEASE TRANSMISSION; HOST RANGE; HYPERSENSITIVITY; MENTAL DEFICIENCY; MOTOR NEURON DISEASE; MOUSE; MUSCLE ATROPHY; NONHUMAN; PRION DISEASE; TRANSGENIC MOUSE; ANIMAL; BRAIN; IMMUNOHISTOCHEMISTRY; ISOLATION AND PURIFICATION; METABOLISM; PATHOGENICITY; PATHOLOGY; SKELETAL MUSCLE;

BOS; BOVINAE; FRIESIA; MUS MUSCULUS;

AMYLOID; ANIMALS; BIOLOGICAL MARKERS; BRAIN; CATTLE; ENCEPHALOPATHY, BOVINE SPONGIFORM; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MUSCLE, SKELETAL; PRPC PROTEINS;

EID: 44949088511     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000075     Document Type: Article

References (28)

1. Watts JC, Balachandran A, Westaway D (2006) The expanding universe of prion diseases. PLoS Pathog 2: 26. doi:10.1371/journal.ppat.0020026.
2. Anderson RM, Donnelly CA, Ferguson NM, Woolhouse MEJ, Watt, et al. (1996) Transmission dynamics and epidemiology of BSE in British cattle. Nature (London) 382: 779-788.
3. Will RG, Ironside JW, Zeidler M, Cousens SN, Estibeiro K, et al. (1996) A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347: 921-925.
4. Bruce ME, Will RG, Ironside JW, McConnell I, Drummond D, et al. (1997) Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 389: 498-501.
5. Collinge J (1999) Variant Creutzfeldt-Jakob disease. Lancet 354: 317-323.
6. Wells GA, Hancock RD, Cooley WA, Richards MS, Higgins RJ, et al. (1989) Bovine spongiform encephalopathy: diagnostic significance of vacuolar changes in selected nuclei of the medulla oblongata. Vet Rec 125: 521-524.
7. Wells GA, Sayers AR, Wilesmith JW (1995) Clinical and epidemiological correlates of the neurohistology of cases of histologically unconfirmed, clinically suspect bovine spongiform encephalopathy. Vet Rec 136: 211-216.
8. Collinge J, Sidle KCL, Meads J, Ironside J, Hill AF (1996) Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. Nature (London) 383: 685-690.
9. Biacabe AG, Laplanche JL, Ryder S, Baron T (2004) Distinct molecular phenotypes in bovine prion diseases. EMBO Rep 5: 110-115.
10. Buschmann A, Gretzschel A, Biacabe AG, Schiebel K, Corona C, et al. (2006) Atypical BSE in Germany-proof of transmissibility and biochemical characterization. Vet Microbiol 117: 103-116.
11. Jacobs JG, Langeveld JP, Biacabe AG, Acutis PL, Polak MP, et al. (2007) Molecular discrimination of atypical bovine spongiform encephalopathy strains from a geographical region spanning a wide area in Europe. J Clin Microbiol 45: 1821-9.
12. Casalone C, Zanusso G, Acutis P, Ferrari S, Capucci L, et al. (2004) Identification of a second bovine amyloidotic spongiform encephalopathy: molecular similarities with sporadic Creutzfeldt-Jakob disease. Proc Natl Acad Sci U S A 101: 3065-70.
13. Capobianco R, Casalone C, Suardi S, Mangieri M, Miccolo C, et al. (2007) Conversion of the BASE prion strain into the BSE strain: the origin of BSE? PLoS Pathog 3: 31. doi:10.1371/journal.ppat.0030031.
14. Brown P, McShane LM, Zanusso G, Detwile L (2006) On the question of sporadic or atypical bovine spongiform encephalopathy and Creutzfeldt-Jakob disease. Emerg Infect Dis 12: 1816-21.
15. Williams ES (2005) Chronic wasting disease. Vet Pathol 42: 530-549.
16. Dupuis L, Mbebi C, Gonzalez de Aguilar JL, Rene F, et al. (2002) Loss of prion protein in a transgenic model of amyotrophic lateral sclerosis. Mol Cell Neurosci 19: 216-24.
17. Cutlip RC, Miller JM, Race RE, Jenny AL, Katz JB, et al. (1994) Intracerebral transmission of scrapie to cattle. J Infect Dis 169: 814-820.
18. Cutlip RC, Miller JM, Lehmkuhl HD (1997) Second passage of a US scrapie agent in cattle. J Comp Pathol 17: 271-275.
19. Konold T, Lee YH, Stack MJ, Horrocks C, Green RB, et al. (2006) Different prion disease phenotypes result from inoculation of cattle with two temporally separated sources of sheep scrapie from Great Britain. BMC Vet Res 2: 31.
20. Konold T, Bone G, Ryder S, Hawkins SA, Courtin F, et al. (2004) Clinical findings in 78 suspected cases of bovine spongiform encephalopathy in Great Britain. Vet Rec 155: 659-66.
21. Beringue V, Andreoletti O, Le Dur A, Essalmani R, Vilotte JL, et al. (2007) A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission. J Neurosci 27: 6965-6971.
22. Kong Q, Zheng M, Casalone C, Qing L, Huang S, et al. (2008) Evaluation of the human transmission risk of an atypical bovine spongiform encephalopathy prion strain. J Virol 82: 3697-701.
23. Bishop MT, Hart P, Aitchison L, Baybutt HN, Plinston C, et al. (2006) Predicting susceptibility and incubation time of human-to-human transmission of vCJD. Lancet Neurol 5: 393-398.
24. Juling K, Schwarzenbacher H, Williams JL, Fries R (2006) A major genetic component of BSE susceptibility. BMC Biol 4: 33.
25. Mayhew LG (1989) Large animal neurology: a handbook for veterinary clinicians. Philadelphia: Eds Lea and Febiger. pp 14-48.
26. Lorenz MD, Kornegay JN (2004) Handbook of veterinary neurology. St. Louis: Eds. Saunders. pp 3-44.
27. Zanusso G, Ferrari S, Cardone F, Zampieri P, Gelati M, et al. (2003) Detection of pathologic prion protein in the olfactory epithelium in sporadic Creutzfeldt-Jakob disease. N Engl J Med 348: 711-719.
28. Simmons MM, Harris P, Jeffrey M, Meek SC, Blamire IW, et al. (1996) BSE in Great Britain: consistency of the neurohistopathological findings in two random annual samples of clinically suspect cases. Vet Rec 138: 175-177.