Insufficient standardization of a direct carbohydrate-deficient transferrin immunoassay

Clinical Chemistry

Volumn 54, Issue 6, 2008, Pages 1090-1092

  Helander, Anders ^a,c   Nordin, Gunnar ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b External Quality Assurance in Laboratory Medicine in Sweden   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE DEFICIENT TRANSFERRIN;

ANALYTIC METHOD; ANION EXCHANGE CHROMATOGRAPHY; CALIBRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOASSAY; LETTER; QUALITY CONTROL; QUANTITATIVE ANALYSIS; STANDARDIZATION;

ALCOHOLISM; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FALSE NEGATIVE REACTIONS; HUMANS; QUALITY CONTROL; REFERENCE STANDARDS; SUBSTANCE ABUSE DETECTION; TRANSFERRIN;

EID: 44849140774     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2007.102145     Document Type: Letter

References (5)

1. Arndt T. Carbohydrate-deficient transferrin as a marker of chronic alcohol abuse: a critical review of preanalysis, analysis, and interpretation. Clin Chem 2001;47:13-27.
2. Helander A, Eriksson G, Stibler H, Jeppsson J-O. Interference of transferrin isoform types with carbohydrate-deficient transferrin quantification in the identification of alcohol abuse. Clin Chem 2001;47:1225-33.
3. Jeppsson J-O, Arndt T, Schellenberg F, Wielders JP, Anton RF, Whitfield JB, Helander A. Toward standardization of carbohydrate-deficient transferrin (CDT) measurements; I, Analyte definition and proposal of a candidate reference method. Clin Chem Lab Med 2007;45:558-62.
4. Helander A, Husa A, Jeppsson J-O. Improved HPLC method for carbohydrate-deficient transferrin in serum. Clin Chem 2003;49:1881-90.
5. Delanghe JR, Helander A, Wielders JP, Pekelharing JM, Roth HJ, Schellenberg F, et al. Development and multicenter evaluation of N Latex CDT, a new direct immunonephelometric assay for carbohydrate-deficient transferrin in human serum. Clin Chem 2007;53:1115-21.