Treatment of Crigler-Najjar Syndrome Type 1 by Hepatic Progenitor Cell Transplantation: A Simple Procedure for Management of Hyperbilirubinemia

Transplantation Proceedings

Volumn 40, Issue 4, 2008, Pages 1148-1150

  Khan, A A ^a   Parveen, N ^a   Mahaboob, V S ^a   Rajendraprasad, A ^a   Ravindraprakash, H R ^b   Venkateswarlu, J ^b   Rao, P ^b   Pande, G ^d   Lakshmi Narusu, M ^c   Khaja, M N ^a   Pramila, R ^c   Habeeb, A ^a   Habibullah, C M ^a  

^a DECCAN COLLEGE OF MEDICAL SCIENCES   (India)

^b Owaisi Hospital   (India)

^c JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

^d CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; BILIRUBIN; BILIRUBIN GLUCURONIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; BILIRUBIN BLOOD LEVEL; CASE REPORT; CELL THERAPY; CLINICAL FEATURE; CRIGLER NAJJAR SYNDROME; FEMALE; FETUS; GENERAL CONDITION IMPROVEMENT; HEPATIC ARTERY; HUMAN; HUMAN CELL; HYPERBILIRUBINEMIA; KERNICTERUS; PRIORITY JOURNAL; SCHOOL CHILD; STEM CELL TRANSPLANTATION; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANIMALS; BILIRUBIN; CHILD, PRESCHOOL; CRIGLER-NAJJAR SYNDROME; DISEASE MODELS, ANIMAL; FEMALE; FETAL TISSUE TRANSPLANTATION; GLUCURONOSYLTRANSFERASE; HEPATIC ARTERY; HEPATOCYTES; HUMANS; HYPERBILIRUBINEMIA; POLYMERASE CHAIN REACTION; STEM CELL TRANSPLANTATION;

EID: 44849124224     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.03.022     Document Type: Article

References (12)

1. Thompson R.P.H. Genetic transmission of Gilbert's syndrome. In: Okolicsanyi L. (Ed). Familial Hyperbilirubinemia (1981), John Wiley, New York 91
2. Crigler Jr. J.F., and Najjar V.A. Congenital familial nonhemolytic jaundice with kernicterus. Pediatrics 10 (1952) 169
3. Pett S., and Mowat A.P. Crigler-Najjar syndromes type I and II: clinical experience King's College Hospital 1972-1978: phenobarbitone, phototherapy and liver transplantation. Mol Aspects Med 9 (1987) 473
4. Matas A.J., Sutherland D.E., Steffes M.W., et al. Hepatocellular transplantation for metabolic deficiencies: decrease of plasms bilirubin in Gunn rats. Science 192 (1976) 892
5. Tada K., Roy-Chowdhury N., Prasad V., et al. Long-term amelioration of bilirubin glucuronidation defect in Gunn rats by transplanting genetically modified immortalized autologous hepatocytes. Cell Transplant 7 (1998) 607
6. Rozga J., Holzman M., Moscioni A.D., et al. Repeated intraportal hepatocyte transplantation in analbuminemic rats. Cell Transplant 4 (1995) 237
7. Wiederkehr J.C., Kondos G.T., and Pollak R. Hepatocyte transplantation for the low-density lipoprotein receptor-deficient state. A study in the Watanabe rabbit. Transplantation 50 (1990) 466
8. Overturf K., Al-Dhalimy M., Tanguay R., et al. Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I. Nat Genet 12 (1996) 266
9. Muraca M., Gerunda G., Neri D., et al. Hepatocyte transplantation as a treatment for glycogen storage disease type 1a. Lancet 359 (2002) 317
10. Fox I.J., Chowdhury J.R., Kaufman S.S., et al. Treatment of the Crigle Najjar syndrome type I with hepatocyte transplantation. N Engl J Med 338 (1998) 1422
11. Horslen S.P., McCowan T.C., Timothy C., et al. Isolated Hepatocyte transplantation in an infant with a severe urea cycle disorder. Pediatrics 111 (2003) 1262
12. Nyamath P., Alvi A., et al. Characterization of hepatic progenitors from human fetal liver using CD34 as a hepatic progenitor marker. World J Gastroenterol 13 (2007) 2319