The severity of malarial anaemia in Plasmodium chabaudi infections of BALB/c mice is determined independently of the number of circulating parasites

Malaria Journal

Volumn 7, Issue , 2008, Pages

  Lamb, Tracey J ^a,b   Langhorne, Jean ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY OF READING   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYSIS OF VARIANCE; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CLONING; CONTROLLED STUDY; DISEASE SEVERITY; ERYTHROCYTE; FEMALE; MALARIA; MOUSE; NONHUMAN; PLASMODIUM CHABAUDI; T LYMPHOCYTE; ANIMAL; BAGG ALBINO MOUSE; HOSPITALIZATION; ISOLATION AND PURIFICATION; MOUSE MUTANT; PARASITEMIA; PARASITOLOGY; STATISTICS;

DNA BINDING PROTEIN; RAG2 PROTEIN, MOUSE;

ANALYSIS OF VARIANCE; ANEMIA; ANIMALS; DNA-BINDING PROTEINS; FEMALE; MALARIA; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PARASITEMIA; PLASMODIUM CHABAUDI; SEVERITY OF ILLNESS INDEX; STATISTICS AS TOPIC;

EID: 44849120376     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-7-68     Document Type: Article

References (39)

1. Severe malarial anaemia. C Casals-Pascual DJ Roberts, Curr Mol Med 2006 6 155 168 10.2174/156652406776055159 16515508
2. Malaria. K Maitland P Bejon CR Newton, Curr Opin Infect Dis 2003 16 389 395 10.1097/00001432-200310000-00004 14501990
3. Insights into the immunopathogenesis of malaria using mouse models. TJ Lamb DE Brown AJ Potocnik J Langhorne, Expert Rev Mol Med 2006 8 1 22 16556343
4. The deoxyuridine suppression test in severe anaemia following Plasmodium falciparum malaria. SH Abdalla SN Wickramasinghe DJ Weatherall, Trans R Soc Trop Med Hyg 1984 78 60 63 10.1016/0035-9203(84)90173-1 6369652
5. Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes. GN Jakeman A Saul WL Hogarth WE Collins, Parasitology 1999 119 127 133 10.1017/S0031182099004564 10466119
6. Factors contributing to anemia after uncomplicated falciparum malaria. RN Price JA Simpson F Nosten C Luxemburger L Hkirjaroen F ter Kuile T Chongsuphajaisiddhi NJ White, Am J Trop Med Hyg 2001 65 614 622 11716124
7. Malarial anemia: of mice and men. AA Lamikanra D Brown A Potocnik C Casals Pascual J Langhorne DJ Roberts, Blood 2007 110 18 28 10.1182/blood-2006- 09-018069 17341664
8. Tumour necrosis factor may contribute to the anaemia of malaria by causing dyserythropoiesis and erythrophagocytosis. IA Clark G Chaudhri, Br J Haematol 1988 70 99 103 10.1111/j.1365-2141.1988.tb02440.x 3179231
9. Severe malarial anemia of low parasite burden in rodent models results from accelerated clearance of uninfected erythrocytes. KJ Evans DS Hansen N van Rooijen LA Buckingham L Schofield, Blood 2006 107 1192 1199 16210332 10.1182/blood-2005-08-3460
10. Plasmodium chabaudi AS: erythropoietic responses during infection in resistant and susceptible mice. GS Yap MM Stevenson, Exp Parasitol 1992 75 340 352 10.1016/0014-4894(92)90219-Z 1426136
11. Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria. P Kern CJ Hemmer J Van Damme HJ Gruss M Dietrich, Am J Med 1989 87 139 143 2667356
12. Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies. C Li LA Sanni F Omer E Riley J Langhorne, Infect Immun 2003 71 4850 4856 12933825 10.1128/IAI.71.9.4850-4856.2003
13. Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls. KE Lyke R Burges Y Cissoko L Sangare M Dao I Diarra A Kone R Harley CV Plowe OK Doumbo MB Sztein, Infect Immun 2004 72 5630 5637 15385460 10.1128/IAI.72.10.5630-5637.2004
14. Cytokines in the pathogenesis of malaria: levels of IL-I beta, IL-4, IL-6, TNF-alpha and IFN-gamma in plasma of healthy individuals and malaria patients in a holoendemic area. RN Mshana J Boulandi NM Mshana J Mayombo G Mendome, J Clin Lab Immunol 1991 34 131 139 1667945
15. Differential induction of TGF-beta regulates proinflammatory cytokine production and determines the outcome of lethal and nonlethal Plasmodium yoelii infections. FM Omer JB de Souza EM Riley, J Immunol 2003 171 5430 5436 14607947
16. Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles. W McGuire JC Knight AV Hill CE Allsopp BM Greenwood D Kwiatkowski, J Infect Dis 1999 179 287 290 10.1086/314533 9841857
17. Tumor necrosis factor alpha and the anemia associated with murine malaria. KL Miller PH Silverman B Kullgren LJ Mahlmann, Infect Immun 1989 57 1542 1546 2707858
18. Anaemia and resistance to malaria in transgenic mice expressing human tumour necrosis factor. J Taverne N Sheikh JB de Souza JH Playfair L Probert G Kollias, Immunology 1994 82 397 403 7959874
19. Strong association of a tumor necrosis factor-alpha promoter allele with cerebral malaria in Myanmar. R Ubalee F Suzuki M Kikuchi O Tasanor Y Wattanagoon R Ruangweerayut K Na-Bangchang J Karbwang A Kimura K Itoh T Kanda K Hirayama, Tissue Antigens 2001 58 407 410 10.1034/j.1399-0039.2001.580610.x 11929592
20. Macrophage migration inhibitory factor release by macrophages after ingestion of Plasmodium chabaudi-infected erythrocytes: possible role in the pathogenesis of malarial anemia. JA Martiney B Sherry CN Metz M Espinoza AS Ferrer T Calandra HE Broxmeyer R Bucala, Infect Immun 2000 68 2259 2267 10722628 10.1128/IAI.68.4.2259-2267.2000
21. A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia. MA McDevitt J Xie G Shanmugasundaram J Griffith A Liu C McDonald P Thuma VR Gordeuk CN Metz R Mitchell J Keefer J David L Leng R Bucala, J Exp Med 2006 203 1185 1196 16636133 10.1084/jem.20052398
22. Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria. JA Kurtzhals V Adabayeri BQ Goka BD Akanmori JO Oliver-Commey FK Nkrumah C Behr L Hviid, Lancet 1998 351 1768 1772 10.1016/S0140-6736(97)09439-7 9635949
23. Anemia and interleukin-10, tumor necrosis factor alpha, and erythropoietin levels among children with acute, uncomplicated Plasmodium falciparum malaria. V Nussenblatt G Mukasa A Metzger G Ndeezi E Garrett RD Semba, Clin Diagn Lab Immunol 2001 8 1164 1170 11687458 10.1128/CDLI.8.6.1164- 1170.2001
24. A low interleukin-10 tumor necrosis factor-alpha ratio is associated with malaria anemia in children residing in a holoendemic malaria region in western Kenya. C Othoro AA Lal B Nahlen D Koech AS Orago V Udhayakumar, J Infect Dis 1999 179 279 282 10.1086/314548 9841855
25. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Y Shinkai G Rathbun KP Lam EM Oltz V Stewart M Mendelsohn J Charron M Datta F Young AM Stall FM Alt, Cell 1992 68 855 867 10.1016/0092-8674(92)90029-C 1547487
26. Genetics. GH Beale R Carter D Walliker, Rodent malaria London: Academic Press Inc, Killick-Kendrick P, Peters, W, 1978 53 84
27. A Grafen R Hails, Modern Statistics for the Life Sciences Oxford: Oxford University Press 2002
28. Malaria-specific transgenic CD4(+) T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance. R Stephens FR Albano S Quin BJ Pascal V Harrison B Stockinger D Kioussis HU Weltzien J Langhorne, Blood 2005 106 1676 1684 10.1182/blood-2004-10-4047 15890689
29. Genetic relationships between parasite virulence and transmission in the rodent malaria Plasmodium chabaudi. MJ MacKinnon AF Read, Evolution 1999 53 689 703 10.2307/2640710
30. Accelerated clearance of uninfected red cells from Plasmodium berghei-infected mouse blood in normal mice. RJ Howard GF Mitchell, Aust J Exp Biol Med Sci 1979 57 455 457 10.1038/icb.1979.46 548017
31. Inappropriately low reticulocytosis in severe malarial anemia correlates with suppression in the development of late erythroid precursors. KH Chang M Tam MM Stevenson, Blood 2004 103 3727 3735 10.1182/blood-2003-08-2887 14739226
32. Complement binding to erythrocytes is associated with macrophage activation and reduced haemoglobin in Plasmodium falciparum malaria. BQ Goka H Kwarko JA Kurtzhals B Gyan E Ofori-Adjei SA Ohene L Hviid BD Akanmori J Neequaye, Trans R Soc Trop Med Hyg 2001 95 545 549 10.1016/S0035-9203(01)90036-7 11706671
33. Plasmodium chabaudi-infected erythrocytes adhere to CD36 and bind to microvascular endothelial cells in an organ-specific way. MM Mota W Jarra E Hirst PK Patnaik AA Holder, Infect Immun 2000 68 4135 4144 10858230 10.1128/IAI.68.7.4135-4144.2000
34. Relationships between sequestration, antigenic variation and chronic parasitism in Plasmodium chabaudi chabaudi - a rodent malaria model. CF Gilks D Walliker CI Newbold, Parasite Immunol 1990 12 45 64 10.1111/j.1365-3024.1990. tb00935.x 2314922
35. Cerebral edema and cerebral hemorrhages in interleukin-10-deficient mice infected with Plasmodium chabaudi. LA Sanni W Jarra C Li J Langhorne, Infect Immun 2004 72 3054 3058 15102820 10.1128/IAI.72.5.3054-3058.2004
36. Invasion of mature and immature erythrocytes of CBA/Ca mice by a cloned line of Plasmodium chabaudi chabaudi. W Jarra KN Brown, Parasitology 1989 99 Pt 2 157 163 2594410
37. Early IL-12 p70, but not p40, production by splenic macrophages correlates with host resistance to blood-stage Plasmodium chabaudi AS malaria. H Sam MM Stevenson, Clin Exp Immunol 1999 117 343 349 10444268 10.1046/j.1365-2249.1999.00966.x
38. Macrophage activation during Plasmodium chabaudi AS infection in resistant C57BL/6 and susceptible A/J mice. MM Stevenson DY Huang JE Podoba ME Nowotarski, Infect Immun 1992 60 1193 1201 1311705
39. Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism. K Adachi H Tsutsui S Kashiwamura E Seki H Nakano O Takeuchi K Takeda K Okumura L Van Kaer H Okamura S Akira K Nakanishi, J Immunol 2001 167 5928 5934 11698470