Clinical efficacy of a chlorhexidine-delivering toothbrush

Journal of Clinical Periodontology

Volumn 35, Issue 7, 2008, Pages 584-590

  Van Strydonck, Danielle A C ^a   Timmerman, Mark F ^a   Van Der Velden, Ubele ^a   Van Der Weijden, Fridus ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Bleeding; Chlorhexidine; Oral tissues; Plaque; Stain; Toothbrush

Indexed keywords

CHLORHEXIDINE; TOPICAL ANTIINFECTIVE AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; CHEMICALLY INDUCED DISORDER; CHI SQUARE DISTRIBUTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; FEMALE; GINGIVA BLEEDING; HUMAN; INSTRUMENTATION; MALE; MIDDLE AGED; MOUTHWASH; PERIODONTICS; RANDOMIZED CONTROLLED TRIAL; TOOTH BRUSHING; TOOTH DISCOLORATION; TOOTH PLAQUE; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; ANTI-INFECTIVE AGENTS, LOCAL; CHI-SQUARE DISTRIBUTION; CHLORHEXIDINE; DELAYED-ACTION PREPARATIONS; DENTAL PLAQUE; DRUG DELIVERY SYSTEMS; FEMALE; GINGIVAL HEMORRHAGE; HUMANS; MALE; MIDDLE AGED; MOUTHWASHES; PERIODONTAL INDEX; TOOTH DISCOLORATION; TOOTHBRUSHING; TREATMENT OUTCOME;

EID: 44849092316     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2008.01227.x     Document Type: Article

References (38)

1. Addems, A., Epstein, J. B., Damji, S. Spinelli, J. (1992) The lack of efficacy of a foam brush in maintaining gingival health: a controlled study. Special Care Dentist 12, 103 106.
2. Addy, M. (1986) Chlorhexidine compared with other locally delivered antimicrobials. A short review. Journal of Clinical Periodontology 13, 957 964.
3. Addy, M. (1995) Evaluation of clinical trials of agents and procedures to prevent caries and periodontal disease: choosing products and recommending procedures. International Dental Journal 45, 185 196.
4. Addy, M. Moran, J. M. (1997) Clinical indications for the use of chemical adjuncts to plaque control: chlorhexidine formulations. Periodontology 2000 15, 52 54.
5. Addy, M., Wade, W. Goodfield, S. (1991) Staining and antimicrobial properties in vitro of some chlorhexidine formulations. Clinical Preventive Dentistry 6, 13 17.
6. Axelsson, P., Lindhe, J. Nystrom, B. (1991) On the prevention of caries and periodontal disease. Results of a 15-year longitudinal study in adults. Journal of Clinical Periodontology 18, 182 189.
7. Bain, M. J. Strahan, J. D. (1978) The effect of a 1% chlorhexidine gel in the initial therapy of chronic periodontal disease. Journal of Periodontology 49, 469 474.
8. Barkvoll, P., Rolla, G. Svendsen, A. K. (1989) Interaction between chlorhexidine gluconate and sodium lauryl sulfate in vivo. Journal of Clinical Periodontology 16, 593 595.
9. Bassiouny, M. A. Grant, A. A. (1975) The toothbrush application of chlorhexidine. British Dental Journal 139, 323 327.
10. Bay, L. M. (1978) Effect of toothbrushing with different concentrations of chlorhexidine on the development of dental plaque and gingivitis. Journal of Dental Research 57, 181 185.
11. Danser, M. M., Timmerman, M. F., IJzerman, Y., Piscaer, M. I., Van der Velden, U. Van der Weijden, G. A. (2003) Plaque removal with a novel manual toothbrush (X-active) and the Braun Oral-B 3D Plaque Remover. Journal of Clinical Periodontology 30, 138 144.
12. Emilson, C. G. Fornell, J. (1976) Effect of toothbrushing with chlorhexidine gel on salivary microflora, oral hygiene, and caries. Scandinavian Journal of Dental Research 84, 308 319.
13. Epstein, J. B., Ransier, A., Lunn, R. Spinelli, J. (1994) Enhancing the effect of oral hygiene with the use of a foam brush with chlorhexidine. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 77, 242 247.
14. Flötra, L. (1973) Different modes of chlorhexidine application and related local side effects. Journal of Periodontal Research 12 (Suppl.), 41 44.
15. Flötra, L., Gjermo, P., Rolla, G. Waerhaug, J. (1971) Side effects of chlorhexidine mouth washes. Scandinavian Journal of Dental Research 79, 119 125.
16. Forward, G. C. (1991) Role of toothpastes in the cleaning of teeth. International Dental Journal 41, 164 170.
17. Gjermo, P., Baastad, K. L. Rölla, G. (1970) The plaque inhibiting capacity of 11 antibacterial compounds. Journal of Clinical Periodontology 1, 143 152.
18. Gjermo, P. Flötra, L. (1970) The effect of different methods of interdental cleaning. Journal of Periodontal Research 5, 230 236.
19. Gründemann, L. J., Timmerman, M. F., IJzerman, Y. Van der Weijden, G. A. (2000) Stain, plaque and gingivitis reduction by combining chlorhexidine and peroxyborate. Journal of Clinical Periodontology 27, 9 15.
20. Hancock, E. B. (1996) Prevention. Annals of Periodontology 1, 223 249.
21. Hansen, F., Gjermo, P. Eriksen, H. M. (1975) The effect of a chlorhexidine-containing gel on oral cleanliness and gingival health in young adults. Journal of Clinical Periodontology 2, 153 159.
22. Keijser, J. A., Verkade, H., Timmerman, M. F. Van der Weijden, F. A. (2003) Comparison of 2 commercially available chlorhexidine mouth rinses. Journal of Periodontology 74, 214 218.
23. Löe, H. Schiött, C. R. (1970) The effect of mouthrinses and topical application of chlorhexidine on the development of dental plaque and gingivitis in man. Journal of Periodontal Research 5, 79 83.
24. Löe, H., Theilade, E. Jensen, S. B. (1965) Experimental gingivitis in man. Journal of Periodontology 36, 177 187.
25. Lobene, R. R. (1968) Effects of dentifrices on tooth stains with controlled brushing. Journal of American Dental Association 77, 849 855.
26. Owens, J., Addy, M., Faulkner, J., Lockwood, C. Adair, R. (1997) A short-term clinical study design to investigate the chemical plaque inhibitory properties of mouthrinses when used as adjuncts to toothpastes: applied to chlorhexidine. Journal of Clinical Periodontology 24, 732 737.
27. Paraskevas, S. (2005) Randomized controlled clinical trials on agents used for chemical plaque control. International Journal of Dental Hygiene 3, 162 178.
28. Paraskevas, S., Timmerman, M. F., Van der Velden, U. Van der Weijden, G. A. (2006) Additional effect of dentifrices on the instant efficacy of toothbrushing. Journal of Periodontology 77, 1522 1527.
29. Ransier, A., Epstein, J. B., Lunn, R. Spinelli, J. (1995) A combined analysis of a toothbrush, foam brush, and a chlorhexidine-soaked foam brush in maintaining oral hygiene. Cancer Nursing 18, 393 396.
30. Saxen, I., Niemi, M. L. Ainamo, J. (1976) Intraoral spread of the antimicrobial effect of a chlorhexidine gel. Scandinavian Journal Dental Research 84, 304 307.
31. Saxton, C. A. Van der Ouderaa, F. J. G. (1989) The effect of a dentifrice containing zinc citrate and Triclosan on developing gingivitis. Journal of Periodontal Research 24, 75 80.
32. Silness, J. Löe, H. (1964) Periodontal disease in pregnancy. Correlation between oral hygiene and periodontal condition. Acta Odontologica Scandinavica 22, 112 135.
33. Stoeken, J. E., Versteeg, P. A., Rosema, N. A. M., Timmerman, M. F., Van der Velden, U. Van der Weijden, G. A. (2007) Inhibition of 'de novo' plaque formation with 0.12% chlorhexidine spray compared to 0.2% spray and 0.2% chlorhexidine mouthwash. Journal of Periodontology 78, 899 904.
34. Usher, P. J. (1975) Oral hygiene in mentally handicapped children. A pilot study of the use of chlorhexidine gel. British Dental Journal 138, 217 221.
35. Van der Weijden, G. A., Timmerman, M. F., Nijboer, A., Reijerse, E. Van der Velden, U. (1994) Comparison of different approaches to assess bleeding on probing as indicators of gingivitis. Journal of Clinical Periodontology 21, 589 594.
36. Van Strydonck, D. A. C., Demoor, Ph., Timmerman, M. F., Van der Velden, U. Van der Weijden, G. A. (2004b) The anti-plaque efficacy of a chlorhexidine mouthrinse used in combination with toothbrushing with dentifrice. Journal of Clinical Periodontology 31, 691 695.
37. Van Strydonck, D. A. C., Scalé, S., Timmerman, M. F., Van der Velden, U. Van der Weijden, G. A. (2004a) Influence of a SLS containing dentifrice on the anti-plaque efficacy of a chlorhexidine mouthrinse. Journal of Clinical Periodontology 31, 219 222.
38. Van Strydonck, D. A. C., Timmerman, M. F., Van der Velden, U. Van der Weijden, G. A. (2006) Chlorhexidine mouthrinse in combination with a SLS-containing dentifrice and a dentifrice slurry. Journal of Clinical Periodontology 33, 340 344.