Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy

Journal of Biomedical Optics

Volumn 13, Issue 1, 2008, Pages

  Jones, Phillip B ^a   Rozkalne, Aneta ^a   Meyer Luehmann, Melanie ^a   Spires Jones, Tara L ^a   Makarova, Alexandra ^a   Kumar, Anand T N ^a   Berezovska, Oksana ^a   Bacskai, Brian B ^a   Hyman, Bradley T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

autofluorescence; data analysis; fluorescence energy transfer; fluorescence lifetime imaging microscopy; protein conformation

Indexed keywords

AUTOFLUORESCENCE; BIOLOGICAL CONDITIONS; CORTICAL NEURONS; FLUORESCENCE ENERGY TRANSFER; FLUORESCENCE LIFETIME IMAGING MICROSCOPY; HISTOLOGICAL SLICES; HUMAN BRAIN; LIFETIME MEASUREMENTS; MISFOLDING; NEUROFIBRILLARY TANGLES; POST-PROCESSING TECHNIQUES; PROTEIN CONFORMATION; TAU PROTEINS; TRANSGENIC MICE; YELLOW FLUORESCENCE PROTEINS;

BRAIN; DATA REDUCTION; ENERGY TRANSFER; FLUORESCENCE; MAMMALS; PROTEINS; TISSUE;

FLUOROPHORES;

MUS MUSCULUS;

ALGORITHM; ANIMAL; ARTICLE; ARTIFACT; COMPARATIVE STUDY; COMPUTER ASSISTED DIAGNOSIS; EVALUATION; FLUORESCENCE MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; IMAGE ENHANCEMENT; IMAGE SUBTRACTION; METHODOLOGY; MOUSE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TRANSGENIC MOUSE;

ALGORITHMS; ANIMALS; ARTIFACTS; FLUORESCENCE RESONANCE ENERGY TRANSFER; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SUBTRACTION TECHNIQUE;

EID: 44849084804     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2837169     Document Type: Article

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