Relation Between Training-Induced Left Ventricular Hypertrophy and Risk for Ventricular Tachyarrhythmias in Elite Athletes

American Journal of Cardiology

Volumn 101, Issue 12, 2008, Pages 1792-1795

  Biffi, Alessandro ^a   Maron, Barry J ^b   Di Giacinto, Barbara ^a   Porcacchia, Paolo ^a   Verdile, Luisa ^a   Fernando, Fredrick ^a   Spataro, Antonio ^a   Culasso, Francesco ^c   Casasco, Maurizio ^a   Pelliccia, Antonio ^a  

^a Institute of Sports Medicine and Science   (Italy)

^b MINNEAPOLIS HEART INSTITUTE FOUNDATION   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ATHLETE; CARDIOVASCULAR MALFORMATION; CONTROLLED STUDY; DISEASE FREE INTERVAL; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; EVALUATION; FEMALE; HEART LEFT VENTRICLE HYPERTROPHY; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE TACHYCARDIA; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; TRAINING;

ADOLESCENT; ADULT; DISEASE PROGRESSION; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; FOLLOW-UP STUDIES; HEART RATE; HEART VENTRICLES; HUMANS; HYPERTROPHY, LEFT VENTRICULAR; INCIDENCE; ITALY; MALE; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SPORTS; TACHYCARDIA, VENTRICULAR; TIME FACTORS;

EID: 44749094406     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2008.02.081     Document Type: Article

References (20)

1. Huston P., Puffer J.C., and MacMillan R.W. The athletic heart syndrome. N Engl J Med 315 (1985) 24-32
2. Maron B.J., and Pelliccia A. The heart of trained athletes: cardiac remodeling and the risks of sports, including sudden death. Circulation 114 (2006) 1633-1644
3. Maron B.J., Pelliccia A., Spataro A., and Granata M. Reduction in left ventricular wall thickness after deconditioning in highly trained Olympic athletes. Br Heart J 69 (1993) 125-128
4. Biffi A., Pelliccia A., Verdile L., Fernando F., Spataro A., Caselli S., Santini M., and Maron B.J. Long-term clinical significance of frequent and complex ventricular tachyarrhythmias in trained athletes. J Am Coll Cardiol 40 (2002) 446-452
5. Italian Society of Sports Cardiology. Standards of dynamic electrocardiography (Holter) in top-ranking athletes of different sports. In: Lubich T., Venerando A., and Zeppilli P. (Eds). Sports Cardiology. 2nd ed. (1989), Aulo Gaggi, Bologna, Italy 355-361
6. Striegel H., Rossner D., Simon P., and Niess A.M. The World Anti-Doping Code 2003: consequences for physicians associated with elite athletes. Int J Sports Med 29 (2005) 1-14
7. Devereux R.B., Alonso D.R., Lutas E.M., Gottlieb G.J., Campo E., Sachs I., and Reichek N. Echocardiographic assessment of left ventricular hypertrophy: comparison with necropsy findings. Am J Cardiol 57 (1986) 450-458
8. Biffi A., Maron B.J., Verdile L., Fernando F., Spataro A., Marcello G., Ciardo R., Ammirati A., Colivicchi F., and Pelliccia A. Impact of deconditioning on ventricular tachyarrhythmias in trained athletes. J Am Coll Cardiol 44 (2004) 1053-1058
9. Adabag A.S., and Maron B.J. Implication of arrhythmias and prevention of sudden death in hypertrophic cardiomyopathy. Ann Noninvasive Electrocardiol 12 (2007) 171-180
10. Spirito P., Watson R.M., and Maron B.J. Relation between extent of left ventricular hypertrophy and occurrence of ventricular tachycardia in hypertrophic cardiomyopathy. Am J Cardiol 60 (1987) 1137-1142
11. Spirito P., Bellone P., Harris K.M., Bernabo P., Bruzzi P., and Maron B.J. Magnitude of left ventricular hypertrophy and risk for sudden death in hypertrophic cardiomyopathy. N Engl J Med 342 (2000) 1778-1785
12. Hart G. Exercise-induced cardiac hypertrophy: a substrate for sudden death in athletes?. Exp Physiol 88 (2003) 639-644
13. Sapoznikov D., Luria M.H., and Gotsman M.S. Changes in sinus RR interval patterns preceding ventricular ectopic beats: assessment in rate enhancement and dynamic heart rate trends. Int J Cardiol 69 (1999) 217-224
14. Iellamo F., Legramante J.M., Pigozzi F., Spataro A., Norbiato G., Lucini D., and Pagani M. Conversion from vagal to sympathetic predominance with strenuous training in high performance world-class athletes. Circulation 105 (2002) 2719-2724
15. Chen L.S., Zhou S., Fishbein M.C., and Chen P.S. New perspectives on the role of autonomic nervous system in the genesis of arrhythmias. J Cardiovasc Electrophysiol 18 (2007) 123-127
16. Pelliccia A., Maron B.J., Spataro A., Proschan M.A., and Spirito P. The upper limit of physiologic cardiac hypertrophy in highly trained elite athletes. N Engl J Med 324 (1991) 295-301
17. Pelliccia A., Maron B.J., Culasso F., Spataro A., and Caselli G. Athlete's heart in women. Echocardiographic characterization of highly trained elite female athletes. JAMA 276 (1996) 211-215
18. Pelliccia A., Culasso F., Di Paolo F.M., and Maron B.J. Physiologic left ventricular cavity dilatation in elite athletes. Ann Intern Med 130 (1999) 23-31
19. Corrado D., Basso C., Pavei A., Michieli P., Schiavon M., and Thiene G. Trends in sudden cardiovascular death in young competitive athletes after implementation of a preparticipation screening program. JAMA 296 (2006) 1593-1601
20. Pelliccia A., Di Paolo F.M., Corrado D., Buccolieri C., Quattrini F.M., Pisicchio C., Spataro A., Biffi A., Granata M., and Maron B.J. Evidence for efficacy of the Italian national pre-participation screening programme for identification of hypertrophic cardiomyopathy in competitive athletes. Eur Heart J 27 (2006) 2196-2200