Solid-phase synthesis of backbone-modified DNA analogs by the boranophosphotriester method using new protecting groups for nucleobases

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 13, 2008, Pages 3783-3786

  Kawanaka, Toshihide ^a   Shimizu, Mamoru ^a   Shintani, Noriko ^a   Wada, Takeshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Boranophosphate DNA; DNA analogs; H Phosphonate DNA; Protecting group; Solid phase synthesis

Indexed keywords

BENZOIC ACID DERIVATIVE; BORON; DEOXYGUANOSINE; DNA; ESTER DERIVATIVE; MERCAPTOETHANOL; NUCLEIC ACID BASE; PHOSPHATE; PHOSPHONIC ACID DERIVATIVE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DNA MODIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE SYNTHESIS;

BORANES; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; DRUG DESIGN; ESTERS; GUANINE; MERCAPTOETHANOL; MODELS, CHEMICAL; MOLECULAR BIOLOGY; MOLECULAR CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDES; PHOSPHATES; PHOSPHONIC ACIDS;

EID: 44749091472     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.05.053     Document Type: Article

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