Con-A conjugated mucoadhesive microspheres for the colonic delivery of diloxanide furoate

International Journal of Pharmaceutics

Volumn 359, Issue 1-2, 2008, Pages 182-189

  Anande, Nalini M ^a   Jain, Sunil K ^a   Jain, Narendra K ^b  

^a GURU GHASIDAS UNIVERSITY   (India)

^b DR H S GOUR UNIVERSITY   (India)

Author keywords

Colon targeting; Concanavalin A; Diloxanide furoate; Gamma scintigraphy; Microspheres

Indexed keywords

AMICLINE; CONCANAVALIN A; DILOXANIDE FUROATE; EUDRAGIT; LECTIN; MICROSPHERE; TECHNETIUM 99M;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; EMULSION; EVAPORATION; GAMMA SCINTIGRAPHY; INFRARED SPECTROSCOPY; INTESTINE FLUID; MALE; MUCOADHESIVE DRUG DELIVERY SYSTEM; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RABBIT; RAT; SIMULATION; STOMACH JUICE; SURFACE PROPERTY; ZETA POTENTIAL;

ADHESIVENESS; AMEBICIDES; ANIMALS; CAPSULES; CHEMISTRY, PHARMACEUTICAL; COLON; CONCANAVALIN A; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FURANS; HYDROGEN-ION CONCENTRATION; LECTINS; MALE; MICROSPHERES; PARTICLE SIZE; POLYMETHACRYLIC ACIDS; RABBITS; RATS; SPECTROPHOTOMETRY, INFRARED;

EID: 44749090580     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.04.009     Document Type: Article

References (17)

1. Atyabi F., Sharma H.L., Mohammad H.A.H., and Fell J.T. In vivo evaluation of a novel gastric retentive formulation based on ion exchange resins. J. Control. Rel. 42 (1996) 105-113
2. Casey D.L., Beihn R.M., Bigenis G.A., and Shambu M.B. Methods for monitoring hard gelatin capsule disintegration times in humans using external scintigraphy. J. Pharm. Sci. 65 (1976) 1412-1413
3. Dubey M.P., Gupta P.S., and Chutanni H.K. Entamide furoate in the treatment of intestinal amoebiasis. J. Trop. Med. Hyg. 68 (1965) 63-66
4. Gregoriadis G., and Florence A.T. Liposomes in drug delivery. Clinical, diagnostic and ophthalmic potential. Drugs 145 (1993) 15-28
5. Jain S.K., Agrawal G.P., and Jain N.K. A novel calcium silicate based microspheres of repaglinide: in vivo investigations. J. Control. Rel. 113 (2006) 111-116
6. Kalb A.J., and Levitzki A. Metal-binding sites of Concanavalin-A and their role in the binding of α-glucose-d-glucopyranoside. Biochemistry 109 (1968) 669-672
7. Kawashia Y., Niwa T., Takeuchi H., Hino T., and Itoh Y. Characterization of polymorphs of tranilast anhydrate and tranilast monohydrate when crystallized by two solvent change spherical crystallization techniques. J. Pharma. Sci. 81 (1991) 472-478
8. Muramatsu N., and Kondo J. An approach to prepare microparticles of uniform size. Microencapsulation 12 (1995) 129-136
9. Olde Damink L.H., Dijkstra P.J., van Luyn M.J., van Wachem P.B., Nieuwenhuis P., and Feijen J. Cross-linking of dermal sheep collagen using a water-soluble carbodiimide. Biomaterials 17 (1996) 765-773
10. Paharia A., Yadav A.K., Jain S.K., Rai G., Pancholi S.S., and Agrawal G.P. Eudragit coated pectin microspheres of 5-fluorouracil for colon targeting. AAPS PharmSciTech. 8 (2007) E1-E6 (article 12)
11. Rai G., Jain S.K., Agrawal S., Bhadra S., Pancholi S.S., and Agrawal G.P. Chitosan hydrochloride based microspheres of Albendazole for colonic drug delivery. Pharmazie 2 (2005) 131-134
12. Sahoo S.K., Mallick A.A., Barik B.B., and Senapati P.C. Formulation and in vitro evaluation of Eudragit microspheres of stavudine. Trop. J. Pharma. Res. 4 (2005) 369-375
13. Santos C.A., Jacob J.S., Hertzog B.A., Freedman B.D., Press D.L., Harnpicharnchai P., and Mathiowitz E. Correlation of two bioadhesion assays: the everted sac technique and the CAHN microbalance. J. Control. Release 61 (1999) 113-122
14. Sharma A., Sharma S., and Khuller G.K. Lectin-functionalized poly (lactide-co-glycolide) nanoparticles as oral/aerosolized antitubercular drug carriers for treatment of tuberculosis. J. Antimicrob. Chemother. 54 (2004) 761-766
15. Swords R., and Cantey R.J. Amoebiasis. Gastroent. Clin. 25 (2002) 28-29
16. Umamaheshwari R.B., and Jain N.K. Receptor mediated targeting of lectin conjugated gliadin nanoparticles in the treatment of Helicobacter pylori. J. Drug Target. 11 (2003) 415-424
17. Yin Y., Chen D., Qiao M., Lu Z., and Hu H. Preparation and evaluation of lectin-conjugated PLGA nanoparticles for oral delivery of thymopentin. J. Control. Release 116 (2006) 337-345